Edward Cheng, MD

Professor, Department of Orthopedic Surgery

Edward Cheng

Contact Info


Office Phone 612-672-7100

Fax 612-273-7959

Office Address:
M Health Clinics and Surgery Center
909 Fulton St SE
4th Floor
Minneapolis, MN 55455

Mailing Address:
University of Minnesota
Department of Orthopedic Surgery
2450 Riverside Avenue South
Suite R200
Minneapolis, MN 55454

Administrative Assistant Name
Carol Skaja-Jacobsen

Administrative Phone

Administrative Email

Administrative Fax Number

Additional Locations


  • Orthopedic Clinic

Professor, Department of Orthopedic Surgery

Adult Reconstruction/Tumor Co-Section Leader

Orthopaedic Surgeon

Medical School, Northwestern University Medical School, Chicago, IL

Combined Orthopedics and Surgery Residency, Harvard Medical School, Boston, MA

General Surgery Residency, Northwestern University, McGaw Medical Center, Chicago, IL

Orthopedic Oncology Fellowship, Massachusetts General Hospital, Boston, MA

Pediatric Orthopedic Oncology Fellowship, Boston Children's Hospital, Boston, MA

My goal is to provide patients with the best care, using evidence available anywhere in the world, in a compassionate and caring manner. My scholarly research and leadership in international organizations keeps me abreast of the most current knowledge, which I use for their benefit. I’m willing to go the extra mile to help patients, even when that requires extra time and effort on my part.


Dr. Cheng is the Mairs Family Professor Endowed Chair and specializes in orthopedic oncology (bone and soft tissue tumors) and adult reconstructive surgery (joint replacement). His research focuses on soft tissue tumors and sarcomas, bone tumors, osteonecrosis (avascular necrosis), and joint replacement. He is the director of the University of Minnesota’s Adult Reconstructive Fellowship Program.


  • Orthopedics
  • Cancer  

Awards & Recognition

  • Distinguished Professor Appointment from Affiliated Zhongshan Hospital, Dalian, China: 2017
  • Guide to America's Top Surgeons: 2016
  • International Association of Orthopaedic Surgeons - Top Doctor: 2015-2017
  • US News and World Report (Top 1% Orthopedic Surgeons in US): 2012
  • Best Doctors in America®: 2011-2012, 2013, 2015-2016
  • Minnesota Monthly Best Doctors for Women: 2011
  • Minnesota Monthly "Top Doctors": 2020
  • Castle Connolly (America's Top Doctors for Cancer): 2005-2007,2009-2012, 2014-2015
  • Mpls.St. Paul Magazine Top Doctors: 2004, 2006, 2012-2018, 2020
  • Mairs Family Endowed Chair in Orthopedic Oncology, University of Minnesota: 2004
  • America’s Top Physicians, Consumers’ Research Council of America: 2004
  • Newsweek Health, Top Cancer Doctors: 2015

Professional Associations

  • Secretary-Treasurer, North America, Association Research Circulation Osseous (ARCO): 2016-Present
  • Editor, Journal of Bone and Joint Surgery - Essential Surgical Techniques
  • President, Musculoskeletal Tumor Society: 2011-2012
  • Musculoskeletal Transplant Foundation-Medical Board of Trustees: 2006-Present
  • American Orthopaedic Association: 2001-Present
  • American College of Surgeons Oncology Group: 2000-Present
  • American Cancer Society: 1991-Present
  • Minnesota Orthopaedic Society: 1992-Present
  • National Osteonecrosis Foundation: 1997-Present
  • American Association of Hip and Knee Surgeons: 1994-Present


Research Summary/Interests

  • Osteonecrosis
  • Arthroplasty
  • Hip and knee surgery
  • Metastatic bone disease
  • Sarcoma
  • Bone neoplasms

Research Funding Grants

  • OREF Fellowship Grant: 2010, 2011, 2012
  • OMeGA Medical Fellowship Grant: 2013-2018


  • Publications on PubMed
  • Gniadek TJ, Arndt PA, Leger RM, Zydowicz D,
    Cheng EY, Zantek ND. Drug-Induced Immune Hemolytic Anemia Associated with Anti-Vanomycin Complicated by a Paraben Antibody. Transfusion. 2017 Oct 8. doi: 10.1111/trf.14362. [Epub ahead of print]. PMID 28990203.2.
  • Ogilvie CM, Cheng EY. What’s New in Primary Bone Tumors, J Bone Joint Surg Am, 2016 Dec 21; 98 (24): 2109-2113. https://doi.org/10.2106/JBJS.16.00996
  • Jones DA, Shideman C, Yuan J, Dusenbery K, Carlos Manivel J, Ogilvie C, Clohisy DR, Cheng EY, Shanley R, Chinsoo Cho L. Management of unplanned excision for soft-tissue sarcoma with preoperative radiotherapy followed by definitive resection. Am J Clin Oncol, 2016 Dec;39(6):586-592.



  • Musculoskeletal tumors
  • Adult reconstruction 
  • surgery
  • Orthopaedic oncology
  • Joint replacement and resurfacing
  • Reconstructive surgery, Metastatic bone disease, Fractures due to a weakened bone from cancer erosion, 
  • Computer assisted surgery and surgical navigation, Osteonecrosis (Avascular Necrosis) of bone

Board Certifications

  • American Board of Orthopaedic Surgery

Clinical Interests

Adult reconstruction surgery; Computer-assisted surgery and surgical navigation; Fractures due to a weakened bone from cancer erosion; Joint replacement and resurfacing; Metastatic bone disease; Musculoskeletal tumors; Orthopedic oncology; Osteonecrosis; Reconstructive surgery

Hospital Privileges

University of Minnesota Medical Center, Fairview