Clinical Trials

Clinical trials strive to find solutions to some of life’s most complex conditions, diseases, and disorders. They are modern medicine’s answer to the questions “why?” and “how?”

Through clinical trials, we find out whether a new treatment works and is safe. For many, they provide hope and promise for an improved quality of life. They are carefully designed research studies that answer specific questions about the effectiveness of preventive techniques, medications, therapies and treatments and surgical techniques.

About the Center for Clinical Trials

The Department of Urology’s Center for Clinical Trials is a clinical research center that helps facilitate innovative new products and medications for the research community and patients by conducting Phase Ⅰ - Ⅳ clinical trials. Phase Ⅰ is the safety and tolerability of treatment in a small number of individuals. Phase Ⅱ is the efficacy of treatment that is proven to be safe for humans. Phase Ⅲ is the comparison of treatment to current FDA approved treatments in a larger group number of participants. Phase Ⅳ is studying the long term data of the treatment after being on the market.

Participation in a clinical trial does not substitute for regular medical care. Discuss participation in clinical trials with your physician. For more information about current clinical trials, or the clinical trial process at the University of Minnesota, please contact either:

Tracy Daye-Groves at [email protected] or 612-625-3319 

Maressa Twedt at [email protected] or 612-626-6661

Clinical Trials by Urology Specialty Area

Interested in participating?  Click an area of your interest to view the clinical trials being conducted.  

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Bladder Cancer Treatments

EG-70 Study

Study Title: A Phase 1/2 of EG-70 as an Intravesical Administration to Patients with BCG-Unresponsive NMBIC

Principal Investigator: Dr. Joseph Zabell

Currently Recruiting

Learn more about this study on ClinicalTrials.gov   

FIDIA Study

Study Title: A phase III, single-arm study to evaluate the efficacy and safety of ONCOFID-P-B (paclitaxel-hyaluronic acid conjugate) administered intravesically to patients with BCG-unresponsive Carcinoma in Situ of the bladder with or without Ta-T1 papillary disease

Principal Investigator: Dr. Hamed Ahmadi

Currently Recruiting

Masonic Cancer Center - Search protocol #URO-2023-31695   

BRIDGE Study

Study Title: A Randomized Phase III Trial of Intravesical BCG versus Intravesical Docetaxel and Gemcitabine Treatment in BCG Naive High-Grade Non-Muscle Invasive Bladder Cancer (BRIDGE)

Principal Investigator: Dr. Hamed Ahmadi

Currently Recruiting

Learn more about this study on UMN Study Finder  

Other Bladder Studies

NGB/UTI Study

Study Title: Immune Modulation Associations with Urinary Tract Infection in People with Neurogenic Bladder

Principal Investigator: Dr. Sean Elliott

Currently Recruiting

Learn more about this study on UMN StudyFinder  

Ostomy 3D Study

Study Title: Ostomy Simulation for Patient Education Prior to Urologic Bowel Diversion Surgeries

Principal Investigator: Dr. Hamed Ahmadi

Currently Recruiting

Learn more about this study on UMN StudyFinder  

Cysview® Blue Light Cystoscopy Registry

Study Title: Cysview® Blue Light Cystoscopy Registry

Principal Investigator: Dr. Hamed Ahmadi 

Co-Investigators: Drs. Joseph Zabell, Subodh Regmi, and Christopher Warlick 

Currently Recruiting

Learn more about this study on ClinicalTrials.gov   

ABX/UTI Study

Study Title: Prophylactic Antibiotic Use to Prevent Urinary Tract Infection Following Radical Cystectomy and Urinary Diversion: Randomized Clinical Trial

Co-Investigators: Drs. Hamed Ahmadi and Joseph Zabell

Currently Recruiting

Learn more about this study on UMN StudyFinder  

STRATA Cxbladder Study

Study Title: Use of a multiplexed molecular biomarker test Cxbladder, in Real World decision making to provide Clinical Utility Using a Randomized Design.

Principal Investigator: Dr. Hamed Ahmadi

Closed to Recruitment

Learn more about this study on UMN Study Finder

Prostate Cancer

Vapor 2 Study

Study Title: Prospective, Multicenter, Single-Arm study of Vanquish Water Vapor Ablation of Prostate Cancer

Principal Investigator: Dr. Christopher Warlick

Currently Recruiting 

Learn more about this study on UMN Study Finder  

Targeted-Ex Study

Study Title: Ex-Vivo Targeted Treatment of Cancerous Extirpated Prostate Tissue

Principal Investigator: Dr. Christopher Warlick

Currently Recruiting

Urine Protein Biomarkers in Prostate Cancer

Study Title: Development of Protein Biomarkers from Urine of Prostate Cancer Patients

Principal Investigator: Dr. Christopher Warlick

Currently Recruiting

Masonic Cancer Center - Search protocol #2021LS041   

Benign Prostatic Hyperplasia

Butterfly Pivotal Study

Study Title: A prospective, randomized, controlled, blinded study to assess the Safety and Efficacy of the Butterfly Medical Prostatic Retraction Device in Benign Prostatic Hyperplasia (BPH) Patients

Principal Investigator: Dr. Michael Borofsky and Dr. Deepak Agarwal

Currently Recruiting

Learn more about this study on UMN Study Finder

Overactive Bladder

Urovant Vibegron Study

Study Title: Composur, A Patient-centric, Phase IV, Open-label, Prospective, Real World US Study to Evaluate Vibegron on Patient Treatment Satisfaction, Quality of Life, and Healthcare Resource Utilization in Patients with Overactive Bladder

Principal Investigator: Dr. Nissrine Nakib

Active, closed to recruiting

Learn more about this study on UMN Study Finder

Urinary Incontinence

Sorry, no clinical trials at our site at this time.

Kidney Stones

Sorry, no clinical trials at our site at this time.

Male Infertility

Sorry, no clinical trials at our site at this time.

Sacral Nerve Neuromodulation Therapy

Sorry, no clinical trials at our site at this time.

Urology Department Collaboration Studies

STRIVE

Study Title: Support for Transgender and Nonbinary Individuals Seeking Vaginoplasty (STRIVE)

Principal Investigator: Dr. Joseph Pariser 

Currently Recruiting

Learn more about this study on ClinicalTrials.gov   

Looking to participate in a study?

Research Ethics at the University of Minnesota

We are committed to protecting research participants, upholding ethical standards, and improving our practice at every step of our work.

Clinical Research Newsletter

Clinical Research Resource Review Process

For more information and worksheets on the Clinical Research Resource Review Process for the department click here.  For more information in general for the Medical Schools Clinical Research Resource Review Process click here.