Advanced Preclinical Imaging Center (APIC)

The Advanced Preclinical Imaging Center (APIC) is a state-of-the-art innovative research facility within the Lillehei Heart Institute (LHI) of the University of Minnesota. It serves as a core translational laboratory and training facility to stimulate discovery and advancement in the fields of cardiovascular and neurological science, interventional radiology, and biomedical engineering. The APIC inspires and facilitates interdepartmental relationships and novel scientific achievements that fully advance LHI’s mission to serve as the world’s premiere campus for education and research dedicated to cardiovascular health.

Novel, revolutionary outcomes are expected from the research performed at APIC. Our research integrates medical device development for cardiovascular care, surgical technique enhancement, resuscitation innovation, and basic science advancement in the fields of biology, neuroscience, and physiology. Additionally, the APIC provides a platform for postdoctoral and medical fellow training opportunities in cardiac surgical procedures, biomedical engineering, interventional cardiology, physiology and neurology.


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Hybrid Surgical Suite

surgical suite

A hybrid interventional angiography surgical suite features the Toshiba Infinix, a superior imaging system for large animal cardiovascular and neurovascular investigations. This system is a fixed floor mounted C-Arm with an innovative multiaxis mechanism, advanced image processing, and 3D imaging technology. It is fully integrated with a hybrid operating table, ultrasound imaging, hemodynamic monitoring, video recording and an adjacent viewing room for observers. This surgical suite is perfect for transcatheter surgery, device development, cardiac, endovascular and interventional studies.

Surgical & Induction Suites

work room

Additional surgical suite is available to allow for simultaneous studies in each surgical suite. An induction space, post-operative area, necropsy suite and autoclave provide ample support for pre- and post-study requirements.



Expertise & Abilities

MRI screen

At APIC, our team can perform and support a range of surgical specialties, including, but not limited to cardiac, endovascular and interventional.  APIC staff can support acute or chronic procedures and studies and work closely with RAR Veterinary staff.




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Engineering & Wet Bench Laboratories

Toshiba Infinix with integrated operating table
Drager Narkomed Anesthesia Machines
Ultralow ‐80 Freezer
Supreme Air LV Bench Fume hood
Biosafety Cabinet
GE C‐Arm
Datex patient monitors
Maquet Surgical Lights 
Instrumentation Laboratory GEM 3500 Blood Gas Analyzer
Siemens Acuson Ultrasound/ICE
Lifepak 12 Defibrillator
Computer with 60” Monitor
Scotman Ice Machine
Portable Anesthesia Machine
Isotemp Shaking and General Purpose Water Bath 
Tuttnauer Autoclave 

Contact APIC

Investigators interested in learning more about APIC are invited to contact APIC to schedule a tour of the facility, have a confidential consult with APIC and discuss how APIC can meet study needs.

Phone: (612) 626-9292

Fax: (612) 626-4967

Email: apiclab@umn.edu