Michael C. Park, MD, PhD

Associate Professor and Resident Program Director, Department of Neurosurgery

Michael C. Park

Contact Info

mcpark@umn.edu

Office Phone 612-624-6666

Administrative Assistant Name
Zhac Rahkonen

Administrative Phone
612-624-6666

Administrative Email
rahko023@umn.edu

Associate Professor and Resident Program Director, Department of Neurosurgery

MnDRIVE Neuromodulation Scholar, Department of Neurosurgery

Assistant Professor, Department of Neurology

Director of Stereotactic and Functional Neurosurgery, Department of Neurosurgery


MD, University of Kansas

Residency in Neurosurgery and Surgery, Rhode Island Hospital, Providence

William P. Van Wagenen Fellowship, Assistance Publique L'Hopital D'Adulte de la Timone

PhD, Department of Molecular and Integrative Physiology, University of Kansas

BA, University of Kansas; BSEE, Cornell University; BA, Cornell University

Internship in General Surgery, Warren Alpert Medical School of Brown University, Providence, RI

Summary

Dr. Park  is the Neurosurgery Department's residency program director, helping train the next generation of neurosurgical leaders. He is also director of Stereotactic and Functional Neurosurgery.

From a research standpoint, Dr. Park focuses primarily on neuromodulation (deep brain stimulation) and he is a collaborator, Principal Investigator or Co-Principal Investigator in numerous active, ongoing projects in that area. In addition, he is a Clinical Core Co-Investigator for the U of M’s Udall Center of Excellence for Parkinson's Disease Research. 

Listed as first author for 7 of the 25 articles he's had published in peer-reviewed journals, Dr. Park was also first author of 3 book chapters. He has spoken to numerous national and international audiences and is currently working closely with Seoul National University in Korea to revitalize a long-term collaborative relationship the department has had with that organization.

Dr. Park received his MD and PhD from the Department of Molecular and Integrative Physiology at the University of Kansas (KU) in Kansas City, KS, and received a Bachelors in Biology from KU in Lawrence, KS, and dual Bachelors in Electrical Engineering and Economics from Cornell University in Ithaca, NY. He was a 2009 recipient of the William P. Van Wagenen Fellowship and studied at the Assistance Publique L’Hopital d’Adulte de la Timone, Marseille, France.

Awards & Recognition

  • Mpls.St.Paul Magazine Top Doctors Rising Stars, 2018
  • Champion of Care, Fairview Hospital, 2015
  • The William P. Van Wagenen Fellowship, 2009
  • The Melvyn M. Gelch, M.D. Award for Advanced Training of Neurosurgical Residents, 2007

Professional Associations

  • American Society for Stereotactic and Functional Neurosurgery (2015-present)
  • Minnesota Neurosurgical Society (2015-present)
  • Council of State Neurosurgical Society (2015-present)
  • Congress of Neurological Surgeons (2006-present)
  • American Association of Neurological Surgeons (2003-present)
  • American Medical Association (1994-present)

Research

Research Summary/Interests

Research Interests

  • Brain structure
  • Neuromodulation
  • Deep brain stimulation
  • Medical device innovation

Research Projects

  1. Collaborator (PI: David Darrow, MD, MPH), Minnesota Spinal Cord Injury and Traumatic Brain Injury Research Grant Program Epidural stimulation for spinal cord injury
  2. PI: Circuit Based Deep Brain Stimulation for Parkinson’s disease; Udall Project 1 Aim 2 and 3 Clinical Trial 
  3. PI: Advanced Neuromodulation Systems, Inc., Continuing access to SJM totally implantable deep brain stimulation system using the BRIO rechargeable system
  4. 0% funded salary support
  5. PI: Clinical Trial C-15-01 03/11/16-12/31/17, Abbott (formerly St. Jude Medical, Inc.), Continuing Access to SJM Totally Implantable Deep Brain Stimulation System Using the Brio Rechargeable System. The goal of this project is to allow patients previously enrolled in the ANS C-07-01 or ANS C-07-05 study protocols to receive the Brio rechargeable system for continued long-term stimulation and continued access to the investigational devices and device accessories
  6. Co-PI (PI: Jerrold L. Vitek, MD), Boston Scientific, Implantable neurostimulator for the treatment of Parkinson’s disease (INTREPID)
  7. Clinical Trial INTREPID A5002 (PI: Cooper, Co-I: Park) 10/1/13-2/28/19, Boston Scientific, Implantable Neurostimulator for the Treatment of Parkinson's Disease
  8. The purpose of this study is to evaluate the safety and effectiveness of Boston Scientific's Vercise Deep Brain Stimulation (DBS) system in the treatment of patients with  advanced levodopa-responsive bilateral Parkinson's disease (PD) which is not adequately controlled with medication
  9. Co-PI (PI: Barry R. Rittberg, MD), Advanced Neuromodulation Systems, Inc., a long-term follow-up study for evaluating patients who have deep brain stimulation system for the adjunctive treatment of major depressive disorder (ANS C-07-05) Goal is to demonstrate the long-term safety and continued efficacy of using subgenual white matter (Brodmann Area 25) DBS as an adjunctive treatment for MDD, single or recurrent episode
  10. Co-PI (PI: Manda Keller-Ross, PhD), pilot study to assess spinal cord stimulation to inhibit afferent feedback during exercise in hypertension
  11. Co-PI (PI: Jerrold L. Vitek, MD), Humanitarian Use Device (HUD): Medtronic DBS Therapy for Dystonia (HDE #H020007)
  12. Co-PI (PI: Scott E. Cooper, MD), preliminary investigation of dynamic neuromodulation and response inhibition
  13. Co-PI (PI: Norem Harel, PhD), pathway-targeted deep brain stimulation for Parkinson’s disease
  14. Co-PI (PI: Susan J. Harkema, PhD), Leona M. & Harry B. Helmsley Charitable Trust, recovery of function, health and quality of life for people with paralysis
  15. Co-PI (PI: Susan J. Harkema, PhD), Craig H. Neilsen Foundation, recovery of cardiovascular function with epidural stimulation after human spinal cord injury.

Research Funding Grants

  • Collaborator, David Darrow, MD, MPH, PI; Minnesota Spinal Cord Injury and Traumatic Brain Injury Research Grant Program, epidural stimulation for spinal cord injury
  • PI, Circuit Based Deep Brain Stimulation for Parkinson’s Disease; Udall Project 1 Aim 2 and 3, Clinical Trial
  • Advanced Neuromodulation Systems, Inc., PI, continuing access to SJM totally implantable deep brain stimulation system using the BRIO rechargeable system

Publications

Publications (most recent)

  • Patriat R, Cooper SC, Duchin Y, Niederer J, Lenglet C, Aman J, Park MC, Vitek J, Harel N. Individualized tractography-based pracellation of the globus pallidus pars interna using 7T MRI in movement disorder patients prior to DBS surgery. NeuroImage. Submitted 10/17/2017.
  • Knoop CD, Kadish R, Hager K, Park MC, Loprinzi P, LaFaver K. Bridging the gaps in patient education for DBS surgery in Parkinson’s disease. Parkinson’s Disease. 2017;2017:9360354. Epub 2017 Aug 7. PMID: 28848685, http://www.ncbi.nlm.nih.gov/pubmed/28848685
  • Hudson HM, Park MC (Co-First Author), Belhaj-Saif A, Cheney PD. Representation of individual forelimb muscles in primary motor cortex. Journal of Neurophysiology 2017 July 1, 118(1):47-63. PMID: 28356482, https://www.ncbi.nlm.nih.gov/pubmed/28356482
  • Page PS, Nazar RG, Park MC, James RF. Copper deficiency myelopathy in setting of advanced degenerative cervical spondylosis. British Journal of Neurosurgery 2015, Sept 4:14,  
    http://www.ncbi.nlm.nih.gov/pubmed/26337459
  • Ferrara JM, Houghton DJ, Knoop C, Park MC. Management of levodopa-induced stereotypic gait disorder with pallidal stimulation. Neurology: Clinical Practice 2014, 4:499-501.
  • Régis J, Carron R, Park MC, Soumare O, Delsanti C, Thomassin JM, Roche PH. Wait-and-see strategy compared with proactive Gamma Knife surgery in patients with intracanalicular vestibular schwannomas: clinical article. Journal of Neurosurgery 2013, 119 Suppl:105-111. PMID: 25077326
    http://www.ncbi.nlm.nih.gov/pubmed/25077326
  • Régis J, Tamura M, Park MC, McGonigal A, Rivière D, Coulon O, Bartolomei F, Girard N, Figarella-Branger D, Chauvel P, Mangin J-F. Subclinical abnormal gyration pattern, a potential anatomical marker of epileptogenic zone in patients with MRI-negative frontal lobe epilepsy. Neurosurgery 2011, 69:80-94. PMID: 21346658, http://www.ncbi.nlm.nih.gov/pubmed/21346658
  • Régis J, Carron R, Park MC, Soumare O, Delsanti C, Thomassin JM, Roche PH. Wait-and-see strategy compared with proactive Gamma Knife surgery in patients with intracanalicular vestibular schwannomas. Journal of Neurosurgery 2010, 113 Suppl:105-111. PMID: 21121792
    http://www.ncbi.nlm.nih.gov/pubmed/21121792
  • Régis J, Carron R, Park M. Is radiosugery a neuromodulation therapy? A 2009 Fabrikant Award Lecture. Journal of Neurooncology 2010, 98:155-162. PMID: 20512398, http://www.ncbi.nlm.nih.gov/pubmed/20512398
  • Arnold PM, Park MC, Newell K, Kepes JJ, Thrasher JB. Thoracic spinal cord compression secondary to metastatic synovial sarcoma: case report. Coluna/Columna 2009, 8:206-211.

Book Chapters

  • Park MC, Goldman MA, Friehs GM, Canavero S. Anatomical methods of cortical localization. In: Textbook of Therapeutic Cortical Stimulation. Canavero S (ed). Nova Science Publications, New York, NY, 2009. pp. 3-16.
  • Park MC, Goldman MA, Belknap TW, Friehs GM. The future of neural interface technology. In: Textbook of Stereotactic and Functional Neurosurgery, Lozano AM, Gildenberg PL, Tasker RR (eds). Springer-Verlag, Heidelberg, Germany, 2009. pp. 3185 - 3200.
  • Park MC, Harrington Jr. JF, Jenis LG, Friehs GM. Chapter 152: Surgical management of segmental spinal instability. In: Schmidek & Sweet Operative Neurosurgical Techniques: Indications, Methods, and Results, 5th ed, Schmidek HH, Roberts DW (eds). Saunders Elsevier, Philadelphia, PA, 2006. pp. 2114-2145.

Abstracts

  • Hudson HM, Griffin DM, Park MC, Belhaj-Saïf A, Cheney PD. Muscle synergies represented in the output of hindlimb M1 in comparison to forelimb M1 of the rhesus macaque. Society for Neuroscience 2010.
  • Weil A, Park MC, Dousset A, Bonaventure P, Regis J, Leveque M. YouTube: a new source of information regarding functional neurosurgery to patients. XIX Congress of the European Society for Stereotactic and Functional Neurosurgery, 2010.
  • Lévêque M, Park MC, Tabouret E, Bouvier C, Peragut J-C, Régis J. Régression spontanée d’un méningiome de la région pinéale [French]. Congrès Neurochirurgie, 2010.
  • Melhaoui A, Park MC, Hayashi M, Bartolomei F, Chauvel P, Régis J. Long-term MRI follow-up after gamma knife radiosurgery for temporal lobe epilepsy. 15th International Meeting of the Leksell Gamma Knife® Society, 2010.
  • Lévêque M, Melhaoui A, Park MC, Yomo S, Donnet A, Régis J. Gamma knife radiosurgery for glossopharyngeal neuralgia: report of 7 cases. 15th International Meeting of the Leksell Gamma Knife® Society, 2010.
  • Lee JK, Melhaoui A, Witjas T, Park MC, Régis J. Vim targeting in gamma knife radiosurgery for intractable tremor: influence of the shot topology on efficacy and safety. 15th International Meeting of the Leksell Gamma Knife® Society, 2010.
  • Park MC, Tamura M, Mangin J-F, McGonigal A, Rivière D, Coulon O, Bartolomei F, Girard N, Chauvel P, Régis J.Characterizing subclinical abnormal gyration patterns related to cortical dysplasia in MRI negative frontal lobe epilepsy. American Association of Neurological Surgeons Annual Meeting, 2010.
  • Duncan J, III, Noren G, Caralopoulos I, Stopa E, Silverberg G, Klinge P, Donahue J, Park M, Miller M, Johanson C. A porcine model of hydrocephalus induced by gamma knife irradiation. 53rd Annual Scientific Meeting of the Society for Research into Hydrocephalus and Spina Bifida, 2009.
  • Friehs G, Penn RD, Park MC, Goldman M, Zerris VA, Hochberg LR, Chen D, Mukand J, Donoghue JP. Initial surgical experience with an intracortical microelectrode array for brain-computer interface applications. Congress of Neurological Surgeons Annual Meeting, 2006.
  • Friehs G, Zerris VA, Park M, Goldman M, Hochberg L, Donoghue J. Experience with a multi-unit brain recording system in humans. AREADNE (Research in Encoding and Decoding of Neural Ensembles), 2006.

Presentations
Invited Oral Presentations at International Professional Meetings, Conferences, etc.

  • “Advances in Deep Brain Stimulation Surgery.” Department of Neurosurgery Grand Rounds, Seoul National University Hospital, Seoul National University, Seoul, South Korea, July 4, 2017
  • “Advances in Deep Brain Stimulation Surgery.” Department of Neurology Grand Rounds, Seoul National University Hospital, Seoul National University, Seoul, South Korea, July 4, 2017
  • “Personalized Medical Devices and Care: Neuromodulation.” Neuromodulation Symposium Emerging Technology Forum, Design of Medical Devices Conference, University of Minnesota, Minneapolis, MN, April 14, 2017
  • “Surgical procedure tutorial: deep brain stimulator implantation.” Design of Medical Devices Conference, University of Minnesota, Minneapolis, MN, April 13, 2017
  • “Subclinical abnormal gyration patterns in MRI-negative frontal lobe epilepsy patients: a potential anatomical marker.” Epilepsy Conference Lecture, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea, October 20, 2010
  • “Intracortical microelectrode array for brain-computer interface and the future of neural interface technology.” Department of Neurosurgery Lecture, Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea, October 20, 2010.

Peer-reviewed Oral Presentations at Professional Meetings, Conferences, etc.

  • “Initial surgical experience with an intracortical microelectrode array for brain-computer interface applications.” Congress of Neurological Surgeons, Chicago, IL, October 7-12, 2006
  • Friehs G, Penn RD, Park MC, Goldman M, Zerris VA, Hochberg LR, Chen D, Mukand J, Donoghue JP. "Initial surgical experience with an intracortical microelectrode array for brain-computer interface applications." Congress of Neurological Surgeons Annual Meeting, 2006
  • “Impact of imaging modality on the preservation of functional hearing after gamma knife surgery for vestibular schwannoma.” 13th International Meeting of the Leksell Gamma Knife® Society, Seoul, South Korea, May 21-25, 2006
  • Park MC, Norén G, Bradford C, Duncan JA, III. "Impact of imaging modality on the preservation of functional hearing after gamma knife surgery for vestibular schwannoma."  13th International Meeting of the Leksell Gamma Knife® Society, 2006
  • “BrainGateTM – first experience with an implantable human neuromotor prosthesis.” North American Neuromodulation Society 9th Annual Meeting, Washington, D.C., November 10-12, 2005
  • Park MC, Zerris V, Hochberg L, Donoghue J, Mukand JA, Friehs G. BrainGateTM – "First experience with an implantable human neuromotor prosthesis."  Proceeding from the 9th Annual Meeting of the North American Neuromodulation Society, Neuromodulation, 2006, 9(1):8-20.

Poster Abstract Presentations at Professional Meetings, Conferences, etc.

  • Hudson HM, Griffin DM, Park MC, Belhaj-Saïf A, Cheney PD. Muscle synergies represented in the output of hindlimb M1 in comparison to forelimb M1 of the rhesus macaque. Society for Neuroscience 2010
  • Weil A, Park MC, Dousset A, Bonaventure P, Regis J, Leveque M. YouTube: a new source of information regarding functional neurosurgery to patients. XIX Congress of the European Society for Stereotactic and Functional Neurosurgery, 2010
  • Lévêque M, Park MC, Tabouret E, Bouvier C, Peragut J-C, Régis J. Régression spontanée d’un méningiome de la région pinéale [French]. Congrès Neurochirurgie, 2010
  • Melhaoui A, Park MC, Hayashi M, Bartolomei F, Chauvel P, Régis J. Long-term MRI follow-up after gamma knife radiosurgery for temporal lobe epilepsy. 15th International Meeting of the Leksell Gamma Knife® Society, 2010
  • Lévêque M, Melhaoui A, Park MC, Yomo S, Donnet A, Régis J. Gamma knife radiosurgery for glossopharyngeal neuralgia: report of 7 cases. 15th International Meeting of the Leksell Gamma Knife® Society, 2010
  • Lee JK, Melhaoui A, Witjas T, Park MC, Régis J. Vim targeting in gamma knife radiosurgery for intractable tremor: influence of the shot topology on efficacy and safety. 15th International Meeting of the Leksell Gamma Knife® Society, 2010
  • Park MC, Tamura M, Mangin J-F, McGonigal A, Rivière D, Coulon O, Bartolomei F, Girard N, Chauvel P, Régis J. Characterizing subclinical abnormal gyration patterns related to cortical dysplasia in MRI negative frontal lobe epilepsy. American Association of Neurological Surgeons Annual Meeting, 2010
  • Duncan J, III, Noren G, Caralopoulos I, Stopa E, Silverberg G, Klinge P, Donahue J, Park M, Miller M, Johanson C. A porcine model of hydrocephalus induced by gamma knife irradiation. 53rd Annual Scientific Meeting of the Society for Research into Hydrocephalus and Spina Bifida, 2009
  • Friehs G, Zerris VA, Park M, Goldman M, Hochberg L, Donoghue J. Experience with a multi-unit brain recording system in humans. AREADNE (Research in Encoding and Decoding of Neural Ensembles), 2006
  • Friehs G, Zerris VA, Park MC, Goldman M, Hochberg L, Mukand J, Donoghue J. BRAINGATE®, a human brain-machine interface: initial experience in an ongoing pilot clinical trial. American Society for Stereotactic and Functional Neurosurgery, 2006.

Clinical

Board Certifications

FAANS (Diplomate of the American Association of Neurological Surgeons)

Clinical Interests

Stereotactic and functional neurosurgery; Neuromodulation; Deep brain stimulation