Neuroanatomy Lab

The Neuroanatomy Lab is a division of the School of Medicines Department of Neurosurgery under the guidance of Andrew Grande, MD; and Michael Park, MD, PhD. The 1,400 square-feet space is dedicated to the advancement of medicine through education and research related to the anatomy of the human brain.

The lab functions as both a resource for residents in clinical training programs and for outside medical industry personnel interested in expanding their understanding of the brain’s anatomical structures. In addition, the lab hosts visiting researchers through its fellowship program. These fellows aggressively pursue novel and innovative solutions to current neurosurgical issues.

The lab also has a strong intradepartmental, multidisciplinary research program with the U's Center for Magnetic Resonance Research focused on high-field MRI solutions for neurological conditions such as trigeminal neuralgia and incidentally found intracranial aneurysms.

Collaborators

Department of Radiology
Bharathi Jagadeesan, MD
Jafar Golzarian, MD
Can Ozutemiz, MD

Department of Neurosurgery
Walter Low, PhD
David Darrow, MD, Neurosurgery
Coridon Quinn IV, MD, Endovascular Surgery Fellow

Center for Magnetic Resonance Research
Pierre-Francios Van de Moortele, MD
Gregor Adriany, PhD
Michael Garwood, PhD
Christophe Lenglet, Phd
Yigitcan Eryaman, PhD
Jan Zimmermann, Phd

Aerospace
Omid Amili, PhD, MD, University of Toledo

Integrative Biology and Physiology
Joseph Metzger, PhD
Anthony Weinhaus, PhD

Neuroscience
Martin Wessendorf, PhD

Biomedical Engineering
Brenda Ogle, PhD
Patrick Alford, PhD

Projects
  • Ultra-high Field Magnetic Resonance Imaging (MRI) Techniques in the Diagnosis and Management of Trigeminal Neuralgia and other
  • Skull base neurovascular disorders
  • Pushing Spatiotemporal Limits for 4DFlow MRI and Dynamic MRA in the Brain at Ultra-High Field
  • Histological analysis of cerebral aneurysms
  • Neutrophil to Lymphocyte Ratio as a predictor of long term outcomes in intracerebral stroke patients
  • Effect of inhaled oxygen on brain MRI
  • Development of radiomic biomarkers for use in precision radiotherapy
  • GBM MRI Machine Learning
  • Retrospective analysis of Chronic Subdural Hematoma outcomes
  • Exploratory dissections of the Trigeminal Nerve
  • Novel skull base surgical target vectors
Publications
  • Omid Amili, Daniele Schiavazzi, Sean MoeN, Bharathi Jagadeesan, Pierre-François Van de Moortele, Filippo Coletti, Hemodynamics in a giant intracranial aneurysm characterized by in vitro 4D flow MRI PLOS ONE, PLoS One. 2018 Jan 4;13(1):e0188323. doi: 10.1371/journal.pone.0188323. eCollection 2018.
  • Baran Bozkurt, Kaan Yagmurlu, Erik H Middlebrooks, Zuzan Cayci, Orhun M Cevik, Ali Karadag, Sean Moen, Necmettin Tanriover, Andrew W Grande, Journal of Visualized Experiments - Fiber Connections of the Supplementary Motor Area Revisited: Methodology of Fiber Dissection, DTI, and Three-Dimensional Documentation  J Vis Exp. 2017 May 23;(123). doi: 10.3791/55681.:
  • Bozkurt B, Yagmurlu K, Middlebrooks E, Cayci Z, Cevik O, Karadag A, Moen S, Yanriover N, Grande AW. Fiber Connections of the Supplementary Morot Area Revisited: Methodology of Fiber Dissection, DTI, and Three-Dimensional Documentation. Journal of Visualization Experiments. 2017, May 23;(123). PMID 28570516. Impact Factor 1.1
  • Bozkurt B, da Silva Centeno R, Chaddad-Neto F, Goiri MA, Karadaq A, Tugcu B, Ovalioglu TC, Tannover N, Kaya S, Yagmurlu K, Grande A. Transcortical Selective Amygdalohippocampectomy Technique through the Middle Temporal Gyrus Revisited. An Anatomical Study Laboratory Investigation. J Clinical Neuroscience, 2016. Dec;34:237-245. PMID: 27499121
  • Bozkurt B, Yagmurlu K, Middlebrooks EH, Karadag A, Ovalioglu, TC, Jagadeesan B, Sandhu G, Tanriover N, Grande AW. The Microsurgical and Tractographic Anatomy of the Supplementary Motor Area Complex in Humans. World Neurosurgery, 2016. November, 95: 99-107. PMID: 27476690. Impact Factor: 2.685.
Current Fellows

Samuel Ndoro
Rajashree Sarkar

Past Fellows

Asha Sude, MD
Huseyin Tore, MD
Muyassar Mikkhailova, MD
Orhn Cevik, MD
Baran Bozkurt, MD
Ali Karadag, MD
Garov Sandhu, MD
Adel Nasar, MD

Contact Info

Sean Moen, Lab Director

Lab Resources