NIH Awards $2.5m R01 Grant to Perlingeiro

The NIH has awarded LHI researcher Rita Perlingeiro, PhD an R01 grant for her project titled "Targeting Dystroglycanopathies using Pluripotent-derived Myogenic Progenitors." The grant provides $2.5m over five years and will allow the Perlingeiro team to continue their studies on stem cell therapy for FKRP-associated dystroglycanopathies. These investigations will focus on understanding the effect of the environment on the engraftment of pluripotent stem cell (PSC)-derived myogenic progenitors, and the molecular signature and long-term regenerative potential of control and gene corrected FKRP mutant PSC-myogenic progenitors.