Wall of Honor (200+ citations)
Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibilitycomplex multimers.
Daniels MA, Jameson SC.
J Exp Med. 2000 Jan 17;191(2):335-46. PMID:10637277 Published January 2017
Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissues.
Casey KA, Fraser KA, Schenkel JM, Moran A, Abt MC, Beura LK, Lucas PJ, Artis D, Wherry EJ, Hogquist K, Vezys V, Masopust D.
J Immunol. 2012 May 15;188(10):4866-75. doi: 10.4049/jimmunol.1200402. Epub 2012 Apr 13. PMID: 22504644. Published May 15, 2012
Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells.
Skon CN, Lee JY, Anderson KG, Masopust D, Hogquist KA, Jameson SC.
Nat Immunol. 2013 Dec;14(12):1285-93. doi: 10.1038/ni.2745. Epub 2013 Oct 27. PMID: 24162775 Published December 2013
Sensing and alarm function of resident memory CD8⁺ T cells.
By: Schenkel JM, Fraser KA, Vezys V, Masopust D.
Nat Immunol. 2013 May;14(5):509-13. doi: 10.1038/ni.2568. Epub 2013 Mar 31. Erratum in: Nat Immunol. 2013 Aug;14(8):876. PMID: 23542740 Published May 2013
Normalizing the environment recapitulates adult human immune traits in laboratory mice.
By: Beura LK, Hamilton SE, Bi K, Schenkel JM, Odumade OA, Casey KA, Thompson EA, Fraser KA, Rosato PC, Filali-Mouhim A, Sekaly RP, Jenkins MK, Vezys V, Haining WN, Jameson SC, Masopust D.
Nature. 2016 Apr 28;532(7600):512-6. doi: 10.1038/nature17655. Epub 2016 Apr 20. PMID: 27096360 Published April 28, 2016
Skin-resident murine dendritic cell subsets promote distinct and opposing antigen-specific T helper cell responses.
By: Igyártó BZ, Haley K, Ortner D, Bobr A, Gerami-Nejad M, Edelson BT, Zurawski SM, Malissen B, Zurawski G, Berman J, Kaplan DH.
Immunity. 2011 Aug 26;35(2):260-72. doi: 10.1016/j.immuni.2011.06.005. Epub 2011 Jul 21. PMID:21782478 Published August 26, 2011
The humoral immune response is initiated in lymph nodes by B cells that acquire soluble antigen directly in the follicles.
By: Pape KA, Catron DM, Itano AA, Jenkins MK.
Immunity. 2007 Apr;26(4):491-502. Epub 2007 Mar 22. PMID:17379546 Published April 26, 2007
Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T-helper 1 central and effector memory cells.
By: Pepper M, Pagán AJ, Igyártó BZ, Taylor JJ, Jenkins MK.
Immunity. 2011 Oct 28;35(4):583-95. doi: 10.1016/j.immuni.2011.09.009. Epub 2011 Oct 20. PMID: 22018468 Published October 28, 2011
Different B cell populations mediate early and late memory during an endogenous immune response.
By: Pape KA, Taylor JJ, Maul RW, Gearhart PJ, Jenkins MK.
Science. 2011 Mar 4;331(6021):1203-7. doi: 10.1126/science.1201730. Epub 2011 Feb 10. PMID:21310965 Published March 4, 2011
Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells.
By:Lee YJ, Holzapfel KL, Zhu J, Jameson SC, Hogquist KA.
Nat Immunol. 2013 Nov;14(11):1146-54. doi: 10.1038/ni.2731. Epub 2013 Oct 6. Erratum in: Nat Immunol. 2014 Mar;15(3):305.PMID:24097110 Published November 2013
Dynamic T cell migration program provides resident memory within intestinal epithelium.
By: Masopust D, Choo D, Vezys V, Wherry EJ, Duraiswamy J, Akondy R, Wang J, Casey KA, Barber DL, Kawamura KS, Fraser KA, Webby RJ, Brinkmann V, Butcher EC, Newell KA, Ahmed R.
J Exp Med. 2010 Mar 15;207(3):553-64. doi: 10.1084/jem.20090858. PMID: 20156972 Published: March 15, 2010
Standardized frozen preparation for transplantation of fecal microbiota for recurrent Clostridium difficile infection.
By: Hamilton MJ, Weingarden AR, Sadowsky MJ, Khoruts A.
Am J Gastroenterol. 2012 May;107(5):761-7. doi: 10.1038/ajg.2011.482. PMID: 22290405 Published: May 2012
Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells.
By: Pape KA, Khoruts A, Mondino A, Jenkins MK.
J Immunol. 1997 Jul 15;159(2):591-8. Published: July 15, 1997
Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus.
By: Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Ortmann WA, Espe KJ, Shark KB, Grande WJ, Hughes KM, Kapur V, Gregersen PK, Behrens TW.
Proc Natl Acad Sci U S A. 2003 Mar 4;100(5):2610-5. PMID: 12604793 Published: MAR 4, 2003
Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire.
By: Burchill MA, Yang J, Vang KB, Moon JJ, Chu HH, Lio CW, Vegoe AL, Hsieh CS, Jenkins MK, Farrar MA.
Immunity. 2008 Jan;28(1):112-21. PMID: 18199418 Published: JAN 18, 2008
CTLA-4 blockade reverses CD8+ T cell tolerance to tumor by a CD4+ T cell- and IL-2-dependent mechanism.
By: Shrikant P, Khoruts A, Mescher MF.
Immunity. 1999 Oct;11(4):483-93. PMID: 10549630 Published: OCT 1 1999
T cell receptor signal strength in Treg and iNKT cell development demonstrated by a novel fluorescent reporter mouse.
By: Moran AE, Holzapfel KL, Xing Y, Cunningham NR, Maltzman JS, Punt J, Hogquist KA.
JOURNAL OF EXPERIMENTAL MEDICINE Volume 208 Issue 6 Pages: 1279-1289 Published: JUN 6 2011
Visualizing the generation of memory CD4 T cells in the whole body
By: Reinhardt, RL; Khoruts, A; Merica, R; Zell, T; Jenkins MK.
NATURE Volume: 410 Issue: 6824 Pages: 101-105 Published: MAR 1 2001
Visualization of specific B and T lymphocyte interactions in the lymph node
By: Garside P, Ingulli E, Merica RR, Johnson JG, Noelle RJ, Jenkins MK.
SCIENCE Volume: 281 Issue: 5373 Pages: 96-99 Published: JUL 3 1998
Distinct dendritic cell populations sequentially present antigen to CD4 T cells and stimulate different aspects of cell-mediated immunity
By: Itano, AA; McSorley SJ, Reinhardt RL, Ehst BD, Ingulli E, Rudensky AY, Jenkins MK.
IMMUNITY Volume: 19 Issue: 1 Pages: 47-57 Published: JUL 2003
In vivo detection of dendritic cell antigen presentation to CD4(+) T cells
By: Ingulli E, Mondino A, Khoruts A, Jenkins MK.
JOURNAL OF EXPERIMENTAL MEDICINE Volume: 185 Issue: 12 Pages: 2133-2141 Published: JUN 16 1997
Naive CD4(+) T cell frequency varies for different epitopes and predicts repertoire diversity and response magnitude
By: Moon, James J.; Chu HH, Pepper M, McSorley SJ, Jameson SC, Kedl RM, Jenkins MK.
IMMUNITY Volume: 27 Issue: 2 Pages: 203-213 Published: AUG 2007
Generation of anergic and potentially immunoregulatory CD25(+)CD4 T cells in vivo after induction of peripheral tolerance with intravenous or oral antigen
By: Thorstenson, KM; Khoruts, A
JOURNAL OF IMMUNOLOGY Volume: 167 Issue: 1 Pages: 188-195 Published: JUL 1 2001
IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3(+) regulatory T cells
By: Burchill, M; Yang J, Vogtenhuber C, Blazar BR, Farrar MA.
JOURNAL OF IMMUNOLOGY Volume: 178 Issue: 1 Pages: 280-290 Published: JAN 1 2007
Inflammatory cytokines provide a third signal for activation of naive CD4(+) and CD8(+) T cells
By: Curtsinger, JM; Schmidt CS, Mondino A, Lins DC, Kedl RM, Jenkins MK, Mescher MF.
JOURNAL OF IMMUNOLOGY Volume: 162 Issue: 6 Pages: 3256-3262 Published: MAR 15 1999
Identification of a novel population of Langerin(+) dendritic cells
By: Bursch, L; Wang L, Igyarto B, Kissenpfennig A, Malissen B, Kaplan DH, Hogquist KA.
JOURNAL OF EXPERIMENTAL MEDICINE Volume: 204 Issue: 13 Pages: 3147-3156 Published: DEC 24 2007
Cutting edge: Type IIFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation
By: Curtsinger, JM; Valenzuela JO, Agarwal P, Lins D, Mescher MF.
JOURNAL OF IMMUNOLOGY Volume: 174 Issue: 8 Pages: 4465-4469 Published: APR 15 2005
Signal 3 determines tolerance versus full activation of naive CD8 T cells: Dissociating proliferation and development of effector function
By: Curtsinger, JM; Lins, DC; Mescher, MF
JOURNAL OF EXPERIMENTAL MEDICINE Volume: 197 Issue: 9 Pages: 1141-1151 Published: MAY 5 2003
Homeostatic expansion and phenotypic conversion of naive T cells in response to self-peptide/MHC ligands
By: Kieper, WC; Jameson, SC
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA Volume: 96 Issue: 23 Pages: 13306-13311 Published: NOV 9 1999
Kruppel-like factor 2 regulates thymocyte and T-cell migration
By: Carlson, C; Endrizzi BT, Wu J, Ding X, Weinreich MA, Walsh ER, Wani MA, Lingrel JB, Hogquist KA, Jameson SC.
NATURE Volume: 442 Issue: 7100 Pages: 299-302 Published: JUL 20 2006
Changes in the Composition of the Human Fecal Microbiome After Bacteriotherapy for Recurrent Clostridium difficile-associated Diarrhea
By: Khoruts, A; Dicksved J, Jansson JK, Sadowsky MJ.
JOURNAL OF CLINICAL GASTROENTEROLOGY Volume: 44 Issue: 5 Pages: 354-360 Published: MAY-JUN 2010
Naive and memory CD4(+) T cell survival controlled by clonal abundance
By: Hataye, J; Moon JJ, Khoruts A, Reilly C, Jenkins MK.
SCIENCE Volume: 312 Issue: 5770 Pages: 114-116 Published: APR 7 2006
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal
By: Fife, B; Pauken KE, Eagar TN, Obu T, Wu J, Tang Q, Azuma M, Krummel MF, Bluestone JA.
NATURE IMMUNOLOGY Volume: 10 Issue: 11 Pages: 1185-U70 Published: NOV 2009
Blocked signal transduction to the ERK and JNKprotein kinases in anergic CD4+ T cells.
Li W, Whaley CD, Mondino A, Mueller DL.
SCIENCE,. 1996 Mar 1;271(5253):1272-6. PMID:8638107 Published: MAR 1 1996
