Publications

The Center for Immunology produces an immense amount of research each year.  The data produced is comprehensive and timely to research across the globe.  Our research is supported by Government, Commercial and Industrial grants and private funds and is produced in our state of the art research facilities.  The research is carried out by faculty members, visiting scholars, post-doctoral fellows, graduate, and undergraduate students and technicians. The Center for Immunology also has a strong collaboration history with colleagues at other Universities and research companies worldwide.

2024 Publications

Roach SN, Shepherd FK, Mickelson CK, Fiege JK, Thielen BK, Pross LM, Sanders AE, Mitchell JS, Robertson M, Fife BT, Langlois RA. 
Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2320303121. doi: 10.1073/pnas.2320303121. Epub 2024 Jul 15. 
PMID: 39008691
 
Rojo MD, Bandyopadhyay I, Burke CM, Sturtz AD, Phillips ES, Matherne MG, Embrey SJ, LaRue R, Qiu Y, Schwertfeger KL, Machado HL.
Life Sci Alliance. 2024 Jul 18;7(10):e202302516. doi: 10.26508/lsa.202302516. Print 2024 Oct. 
PMID: 39025525

An exercise in relaxation: right ventricular diastolic function predicts exercise capacity in pulmonary arterial hypertension. 
Patterson MT, Prins KW. 
Eur Respir J. 2024 Jul 18;64(1):2401142. doi: 10.1183/13993003.01142-2024. Print 2024 Jul. 
PMID: 39025515

"Couple's Immunotherapy": Is CXCL13 at the Heart of the Prescription? 
Cruz-Hinojoza E, Stromnes IM. 
Cancer Immunol Res. 2024 Jul 5:OF1-OF2. doi: 10.1158/2326-6066.CIR-24-0481. Online ahead of print. 
PMID: 38967231

Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency. 
Wilkie H, Das M, Pelovitz T, Bainter W, Woods B, Alasharee M, Sobh A, Baris S, Eltan SB, Al-Herz W, Barbouche MR, Ben-Mustapha I, Ben-Ali M, Sallam MTH, Awad A, Lotfy S, El Marsafy A, Ezzelarab M, Farrar M, Schmidt BAR, NandyMazumdar M, Guttman-Yassky E, Sheets A, Vidic KM, Murphy G, Schlievert PM, Chou J, Leyva-Castillo JM, Janssen E, Timilshina M, Geha RS.
J Allergy Clin Immunol. 2024 Jul;154(1):143-156. doi: 10.1016/j.jaci.2023.12.020. Epub 2024 Jan 5. 
PMID: 38185418

Circulating KLRG1+ long-lived effector memory T cells retain the flexibility to become tissue resident. 
Lucas ED, Huggins MA, Peng C, O'Connor C, Gress AR, Thefaine CE, Dehm EM, Kubota Y, Jameson SC, Hamilton SE. 
Sci Immunol. 2024 Jun 28;9(96):eadj8356. doi: 10.1126/sciimmunol.adj8356. Epub 2024 Jun 28. 
PMID: 38941479

Dynamic landscapes and protective immunity coordinated by influenza-specific lung-resident memory CD8+ T cells revealed by intravital imaging. 
van de Wall S, Anthony SM, Hancox LS, Pewe LL, Langlois RA, Zehn D, Badovinac VP, Harty JT.
Immunity. 2024 Jul 13:S1074-7613(24)00322-4. doi: 10.1016/j.immuni.2024.06.016. Online ahead of print. 
PMID: 39043185

Vardam-Kaur T, Banuelos A, Gabaldon-Parish M, Macedo BG, Salgado CL, Wanhainen KM, Zhou MH, van Dijk S, Santiago-Carvalho I, Beniwal AS, Leff CL, Peng C, Tran NL, Jameson SC, Borges da Silva H. 
iScience. 2024 Jun 17;27(7):110290. doi: 10.1016/j.isci.2024.110290. eCollection 2024 Jul 19.
PMID: 39045105
 
Maurice NJ, Dalzell TS, Jarjour NN, DePauw TA, Jameson SC. 
bioRxiv [Preprint]. 2024 Jun 12:2024.06.10.598293. doi: 10.1101/2024.06.10.598293. 
PMID: 38915668
Mi T, Soerens AG, Alli S, Kang TG, Vasandan AB, Wang Z, Vezys V, Kimura S, Iacobucci I, Baylin SB, Jones PA, Hiner C, Mueller A, Goldstein H, Mullighan CG, Zebley CC, Masopust D, Youngblood B. 
Nat Aging. 2024 Jun 12. doi: 10.1038/s43587-024-00649-5. Online ahead of print. 
PMID: 38867059
 
Block KE, Jameson SC. 
Immunity. 2024 Jun 11;57(6):1184-1186. doi: 10.1016/j.immuni.2024.05.014. 
PMID: 38865962

Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion. 
Kim JH, Schulte AJ, Sarver AL, Lee D, Angelos MG, Frantz AM, Forster CL, O'Brien TD, Cornax I, O'Sullivan MG, Cheng N, Lewellen M, Oseth L, Kumar S, Bullman S, Pedamallu CS, Goyal SM, Meyerson M, Lund TC, Breen M, Lindblad-Toh K, Dickerson EB, Kaufman DS, Modiano JF. 
Cancer Res Commun. 2024 Jun 11;4(6):1467-1480. doi: 10.1158/2767-9764.CRC-23-0441.
PMID: 38757809

Jarjour NN, Dalzell TS, Maurice NJ, Wanhainen KM, Peng C, DePauw TA, Block KE, Valente WJ, Ashby KM, Masopust D, Jameson SC. 
bioRxiv [Preprint]. 2024 Jun 3:2024.05.31.596695. doi: 10.1101/2024.05.31.596695. 
PMID: 38895229
 
Elfstrum AK, Rumahorbo AH, Reese LE, Nelson EV, McCluskey BM, Schwertfeger KL. 
Cancer Res Commun. 2024 May 31;4(5):1380-1397. doi: 10.1158/2767-9764.CRC-24-0205. 
PMID: 38717149
Liu Q, Pickett T, Hodge D, Rios C, Arnold M, Dong G, Hamilton SE, Rehermann B.
Nat Immunol. 2024 May 15. doi: 10.1038/s41590-024-01842-9. Online ahead of print. 
PMID: 38750319.
 
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. 
Rasmussen DM, Semonis MM, Greene JT, Muretta JM, Thompson AR, Toledo Ramos S, Thomas DD, Pomerantz WCK, Freedman TS, Levinson NM. 
Elife. 2024 May 14;13:RP95481. doi: 10.7554/eLife.95481. 
PMID: 38742856
 

Successful Treatment of Recurrent Clostridioides difficile Infection Using a Novel, Drinkable, Oral Formulation of Fecal Microbiota. 
Sadowsky MJ, Matson M, Mathai PP, Pho M, Staley C, Evert C, Weldy M, Khoruts A. 
Dig Dis Sci. 2024 May;69(5):1778-1784. doi: 10.1007/s10620-024-08351-7. Epub 2024 Mar 8.
PMID: 38457115

PD1 blockade improves survival and CD8+ cytotoxic capacity, without increasing inflammation, during normal microbial experience in old mice. 
Dahlquist KJV, Huggins MA, Yousefzadeh MJ, Soto-Palma C, Cholensky SH, Pierson M, Smith DM, Hamilton SE, Camell CD. 
Nat Aging. 2024 Apr 30. doi: 10.1038/s43587-024-00620-4. Online ahead of print. 
PMID: 38689133

Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses. 
Stolley JM, Scott MC, O'Flanagan SD, Künzli M, Matson CA, Weyu E, Langlois RA, Vezys V, Masopust D.
J Immunol. 2024 Apr 15:ji2400010. doi: 10.4049/jimmunol.2400010. Online ahead of print. 
PMID: 38619284

Short Report: CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation. 
Wardell CM, Fung VCW, Chen E, Haque M, Gillies J, Spanier JA, Mojibian M, Fife BT, Levings MK. 
bioRxiv [Preprint]. 2024 Apr 10:2024.04.06.588414. doi: 10.1101/2024.04.06.588414. 
PMID: 38645184

Peptide targeting improves the delivery and therapeutic index of glucocorticoids to treat rheumatoid arthritis. 
Wu X, Guo H, Gao H, Li Y, Hu X, Kowalke MA, Li YX, Wei Y, Zhao J, Auger J, Binstadt BA, Pang HB.
J Control Release. 2024 Apr;368:329-343. doi: 10.1016/j.jconrel.2024.02.040. Epub 2024 Mar 5. PMID: 38431094

Profibrotic VEGFR3-Dependent Lymphatic Vessel Growth in Autoimmune Valvular Carditis. 
Osinski V, Yellamilli A, Firulyova MM, Zhang MJ, Peck AL, Auger JL, Faragher JL, Marath A, Voeller RK, O'Connell TD, Zaitsev K, Binstadt BA. 
Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):807-821. doi: 10.1161/ATVBAHA.123.320326. Epub 2024 Jan 25.
PMID: 38269589

Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue during sepsis. 
Carey A, Nguyen K, Kandikonda P, Kruglov V, Bradley C, Dahlquist KJV, Cholensky S, Swanson W, Badovinac VP, Griffith TS, Camell CD. 
Cell Rep. 2024 Mar 15;43(3):113967. doi: 10.1016/j.celrep.2024.113967. Online ahead of print. 
PMID: 38492219

IL-15 Complex-Induced IL-10 Enhances Plasmodium-specific CD4+ T Follicular Helper Differentiation and Antibody Production. 
Bravo M, Dileepan T, Dolan M, Hildebrand J, Wolford J, Hanson ID, Hamilton SE, Frosch AE, Burrack KS.
J Immunol. 2024 Mar 15;212(6):992-1001. doi: 10.4049/jimmunol.2300525.
PMID: 38305633

Mouse Models of Sepsis. 
Kannan SK, Kim CY, Heidarian M, Berton RR, Jensen IJ, Griffith TS, Badovinac VP.
Curr Protoc. 2024 Mar;4(3):e997. doi: 10.1002/cpz1.997.
PMID: 38439603

Defining and targeting macrophage heterogeneity in the mammary gland and breast cancer. 
Elfstrum AK, Bapat AS, Schwertfeger KL. 
Cancer Med. 2024 Feb;13(3):e7053. doi: 10.1002/cam4.7053. 
PMID: 38426622

A guide to thymic selection of T cells. 
Ashby KM, Hogquist KA. 
Nat Rev Immunol. 2024 Feb;24(2):103-117. doi: 10.1038/s41577-023-00911-8. Epub 2023 Jul 18.
PMID: 37464188

Comparison of mouse models of microbial experience reveals differences in microbial diversity and response to vaccination. 
Sanders AE, Arnesen H, Shepherd FK, Putri DS, Fiege JK, Pierson MJ, Roach SN, Carlsen H, Masopust D, Boysen P, Langlois RA. 
mSphere. 2024 Jan 29:e0065423. doi: 10.1128/msphere.00654-23. Online ahead of print. 
PMID: 38286428

To die or not to die: Gasdermins in intestinal health and disease. 
Lin Z, Chen Q, Ruan HB. 
Semin Immunol. 2024 Feb;71:101865. doi: 10.1016/j.smim.2024.101865. Epub 2024 Jan 16. 
PMID: 38232665

Centrosomal Protein 55 (CEP55) Drives Immune Exclusion and Resistance to Immune Checkpoint Inhibitors in Colorectal Cancer. 
Wangmo D, Gates TJ, Zhao X, Sun R, Subramanian S. 
Vaccines (Basel). 2024 Jan 8;12(1):63. doi: 10.3390/vaccines12010063. 
PMID: 38250876

Treg cell dysfunction and cutaneous exposure to S. aureus underlie eczema in DOCK8 deficiency. 
Wilkie H, Das M, Pelovitz T, Bainter W, Woods B, Alasharee M, Sobh A, Baris S, Eltan SB, Al-Herz W, Barbouche MR, Ben-Mustapha I, Ben-Ali M, Sallam MTH, Awad A, Lotfy S, El Marsafy A, Ezzelarab M, Farrar M, Schmidt BAR, NandyMazumdar M, Guttman-Yassky E, Sheets A, Vidic KM, Murphy G, Schlievert PM, Chou J, Leyva-Castillo JM, Janssen E, Timilshina M, Geha RS.
 J Allergy Clin Immunol. 2024 Jan 5:S0091-6749(24)00005-8. doi: 10.1016/j.jaci.2023.12.020. Online ahead of print. 
PMID: 38185418

Long- and short-term effects of fecal microbiota transplantation on antibiotic resistance genes: results from a randomized placebo-controlled trial. 
Rashidi A, Ebadi M, Rehman TU, Elhusseini H, Kazadi D, Halaweish H, Khan MH, Hoeschen A, Cao Q, Luo X, Kabage AJ, Lopez S, Holtan SG, Weisdorf DJ, Liu C, Ishii S, Khoruts A, Staley C. 
Gut Microbes. 2024 Jan-Dec;16(1):2327442. doi: 10.1080/19490976.2024.2327442. Epub 2024 Mar 13. 
PMID: 38478462

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2023 Publications

Tumor-derived extracellular vesicles in the colorectal cancer immune environment and immunotherapy. 
Prakash A, Gates T, Zhao X, Wangmo D, Subramanian S.
Pharmacol Ther. 2023 Jan;241:108332. doi: 10.1016/j.pharmthera.2022.108332. Epub 2022 Dec 14.
PMID: 36526013

Inefficient Recovery of Repeatedly Stimulated Memory CD8 T Cells after Polymicrobial Sepsis Induction Leads to Changes in Memory CD8 T Cell Pool Composition. 
Moioffer SJ, Berton RR, McGonagill PW, Jensen IJ, Griffith TS, Badovinac VP.
J Immunol. 2023 Jan 15;210(2):168-179. doi: 10.4049/jimmunol.2200676.
PMID: 36480268

2015-2022 Publications

Wall of Honor

IMMUNOLOGY-cfi_wall_of_honor.jpg

To honor the Center for Immunology faculty with 200 or more citations on one paper we have created a wall of honor located on the second floor of WMBB.