Publications
The Center for Immunology produces an immense amount of research each year. The data produced is comprehensive and timely to research across the globe. Our research is supported by Government, Commercial and Industrial grants and private funds and is produced in our state of the art research facilities. The research is carried out by faculty members, visiting scholars, post-doctoral fellows, graduate, and undergraduate students and technicians. The Center for Immunology also has a strong collaboration history with colleagues at other Universities and research companies worldwide.
2025 Publications
Clin Chest Med. 2025 Mar;46(1):61-75. doi: 10.1016/j.ccm.2024.10.005. Epub 2024 Nov 29.
PMID: 39890293
Cell Rep. 2025 Jan 28;44(1):115111. doi: 10.1016/j.celrep.2024.115111. Epub 2024 Dec 25.
PMID: 39723889
Nat Commun. 2025 Jan 25;16(1):1034. doi: 10.1038/s41467-025-56375-y.
PMID: 39863610
CD44 in myEloid cells is a major driver of liver inflammation and injury in alcohol-related liver disease.
Hepatology. 2025 Jan 14. doi: 10.1097/HEP.0000000000001232. Online ahead of print.
PMID: 39808819
Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence.
Immunity. 2025 Jan 14;58(1):162-181.e10. doi: 10.1016/j.immuni.2024.11.007. Epub 2024 Dec 20.
PMID: 39708817
J Hepatol. 2025 Jan 10:S0168-8278(25)00005-4. doi: 10.1016/j.jhep.2024.12.047. Online ahead of print.
PMID: 39800192
STAR Protoc. 2025 Jan 8;6(1):103535. doi: 10.1016/j.xpro.2024.103535. Online ahead of print.
PMID: 39792561
Tissue Eng Regen Med. 2025 Jan;22(1):43-55. doi: 10.1007/s13770-024-00685-7. Epub 2024 Dec 30.
PMID: 39738937
2024 Publications
A minority of Th1 and Tfh effector cells express survival genes shared by memory cell progeny that require IL-7 or TCR signaling to persist.
Cell Rep. 2024 Dec 25;44(1):115111. doi: 10.1016/j.celrep.2024.115111. Online ahead of print.
PMID: 39723889
Nat Cardiovasc Res. 2024 Nov 29. doi: 10.1038/s44161-024-00571-4. Online ahead of print.
PMID: 39613874
Nat Rev Immunol. 2024 Nov 19. doi: 10.1038/s41577-024-01108-3. Online ahead of print.
PMID: 39562646
J Immunol. 2024 Nov 15;213(10):1452-1466. doi: 10.4049/jimmunol.2400395.
PMID: 39392378
Cell. 2024 Oct 30:S0092-8674(24)01158-9. doi: 10.1016/j.cell.2024.10.010. Online ahead of print.
PMID: 39500322
Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis development in mice.
Nat Commun. 2024 Oct 19;15(1):9027. doi: 10.1038/s41467-024-53267-5.
PMID: 39424804
Ferroptosis Mediated Inflammation Promotes Pulmonary Hypertension.
Circ Res. 2024 Oct 18. doi: 10.1161/CIRCRESAHA.123.324138. Online ahead of print.
PMID: 39421926
Frequency of chloroquine-resistant haplotype of Plasmodium falciparum (CVIET) in Ibadan, Southwest Nigeria 17 years post-chloroquine withdrawal.
Acta Trop. 2024 Oct 15;260:107435. doi: 10.1016/j.actatropica.2024.107435. Online ahead of print.
PMID: 39413897
Surviving septic patients endotyped with a functional assay demonstrate active immune responses.
Front Immunol. 2024 Oct 14;15:1418613. doi: 10.3389/fimmu.2024.1418613. eCollection 2024.
PMID: 39469706
B-cell Interleukin 1 Receptor 1 (IL1R1) modulates the female adipose tissue immune microenvironment during aging.
J Leukoc Biol. 2024 Oct 8:qiae219. doi: 10.1093/jleuko/qiae219. Online ahead of print.
PMID: 39378334
CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes.
Immunity. 2024 Oct 8;57(10):2399-2415.e8. doi: 10.1016/j.immuni.2024.07.024. Epub 2024 Aug 29.
PMID: 39214091
J Immunol Methods. 2024 Oct;533:113743. doi: 10.1016/j.jim.2024.113743.
PMID: 39147231
2024 Publications
Implantation of Islets Co-Seeded with Tregs in a Novel Biomaterial Reverses Diabetes in the NOD Mouse Model.
Tissue Eng Regen Med. 2024 Dec 30. doi: 10.1007/s13770-024-00685-7. Online ahead of print.
PMID: 39738937
A minority of Th1 and Tfh effector cells express survival genes shared by memory cell progeny that require IL-7 or TCR signaling to persist.
Cell Rep. 2024 Dec 25;44(1):115111. doi: 10.1016/j.celrep.2024.115111. Online ahead of print.
PMID: 39723889
Deep profiling deconstructs features associated with memory CD8+ T cell tissue residence.
Immunity. 2024 Dec 3:S1074-7613(24)00522-3. doi: 10.1016/j.immuni.2024.11.007. Online ahead of print.
PMID: 39708817
Nat Cardiovasc Res. 2024 Nov 29. doi: 10.1038/s44161-024-00571-4. Online ahead of print.
PMID: 39613874
Nat Rev Immunol. 2024 Nov 19. doi: 10.1038/s41577-024-01108-3. Online ahead of print.
PMID: 39562646
J Immunol. 2024 Nov 15;213(10):1452-1466. doi: 10.4049/jimmunol.2400395.
PMID: 39392378
Cell. 2024 Oct 30:S0092-8674(24)01158-9. doi: 10.1016/j.cell.2024.10.010. Online ahead of print.
PMID: 39500322
Glucose metabolism controls monocyte homeostasis and migration but has no impact on atherosclerosis development in mice.
Nat Commun. 2024 Oct 19;15(1):9027. doi: 10.1038/s41467-024-53267-5.
PMID: 39424804
Ferroptosis Mediated Inflammation Promotes Pulmonary Hypertension.
Circ Res. 2024 Oct 18. doi: 10.1161/CIRCRESAHA.123.324138. Online ahead of print.
PMID: 39421926
Frequency of chloroquine-resistant haplotype of Plasmodium falciparum (CVIET) in Ibadan, Southwest Nigeria 17 years post-chloroquine withdrawal.
Acta Trop. 2024 Oct 15;260:107435. doi: 10.1016/j.actatropica.2024.107435. Online ahead of print.
PMID: 39413897
Surviving septic patients endotyped with a functional assay demonstrate active immune responses.
Front Immunol. 2024 Oct 14;15:1418613. doi: 10.3389/fimmu.2024.1418613. eCollection 2024.
PMID: 39469706
B-cell Interleukin 1 Receptor 1 (IL1R1) modulates the female adipose tissue immune microenvironment during aging.
J Leukoc Biol. 2024 Oct 8:qiae219. doi: 10.1093/jleuko/qiae219. Online ahead of print.
PMID: 39378334
CD4+ T cells reactive to a hybrid peptide from insulin-chromogranin A adopt a distinct effector fate and are pathogenic in autoimmune diabetes.
Immunity. 2024 Oct 8;57(10):2399-2415.e8. doi: 10.1016/j.immuni.2024.07.024. Epub 2024 Aug 29.
PMID: 39214091
J Immunol Methods. 2024 Oct;533:113743. doi: 10.1016/j.jim.2024.113743.
PMID: 39147231
Early intermittent hyperlipidaemia alters tissue macrophages to fuel atherosclerosis.
Nature. 2024 Oct;634(8033):457-465. doi: 10.1038/s41586-024-07993-x. Epub 2024 Sep 4.
PMID: 39231480
J Immunol Methods. 2024 Oct;533:113743. doi: 10.1016/j.jim.2024.113743. Epub 2024 Aug 13.
PMID: 39147231
Microbiol Spectr. 2024 Sep 30:e0068024. doi: 10.1128/spectrum.00680-24. Online ahead of print.
PMID: 39345212
bioRxiv [Preprint]. 2024 Sep 26:2024.09.24.614807. doi: 10.1101/2024.09.24.614807.
PMID: 39386558
bioRxiv [Preprint]. 2024 Sep 23:2023.01.19.524721. doi: 10.1101/2023.01.19.524721.
PMID: 36712076
Alzheimers Dement. 2024 Sep 23. doi: 10.1002/alz.14222. Online ahead of print.
PMID: 39308178
Protocol to examine murine visceral adipose tissue immune cells using fluorescence-based flow cytometry.
STAR Protoc. 2024 Sep 20;5(3):103227. doi: 10.1016/j.xpro.2024.103227. Epub 2024 Aug 10.
PMID: 39126656
Protocol for inducing monomicrobial sepsis in mice with uropathogenic E. coli.
STAR Protoc. 2024 Sep 20;5(3):103206. doi: 10.1016/j.xpro.2024.103206. Epub 2024 Jul 27.
PMID: 39068653
TREM2 macrophages mediate the beneficial effects of bariatric surgery against MASH.
Hepatology. 2024 Sep 18. doi: 10.1097/HEP.0000000000001098.
PMID: 39292863
Impact of antimicrobials on penile HIV susceptibility and immunology in uncircumcised men: A randomized phase 1/2 clinical trial.
Cell Rep Med. 2024 Sep 17;5(9):101705. doi: 10.1016/j.xcrm.2024.101705. Epub 2024 Aug 29.
PMID: 39214083
Front Immunol. 2024 Sep 2;15:1419527. doi: 10.3389/fimmu.2024.1419527.
PMID: 39286244
Human ACE2 Gene Replacement Mice Support SARS-CoV-2 Viral Replication and Nonlethal Disease Progression.
Immunohorizons. 2024 Sep 1;8(9):712-720. doi: 10.4049/immunohorizons.2400030.
PMID: 39287601
Novel chemokine biomarkers in melanoma†.
J Pathol. 2024 Sep;264(1):1-3. doi: 10.1002/path.6323. Epub 2024 Jun 25.
PMID: 38922893
Role for BLT1 in regulating inflammation within adipose tissue immune cells of aged mice.
Immun Ageing. 2024 Aug 26;21(1):57. doi: 10.1186/s12979-024-00461-0.
PMID: 39187841
Toxicity Profile of eBAT, a Bispecific Ligand-Targeted Toxin Directed to EGFR and uPAR, in Mice and a Clinical Dog Model.
Toxins (Basel). 2024 Aug 26;16(9):376. doi: 10.3390/toxins16090376.
PMID: 39330834
Vet Immunol Immunopathol. 2024 Aug 21;275:110816. doi: 10.1016/j.vetimm.2024.110816.
PMID: 39173398
Front Immunol. 2024 Aug 15;15:1440045. doi: 10.3389/fimmu.2024.1440045. eCollection 2024.
PMID: 39211046
Immunity. 2024 Aug 13;57(8):1878-1892.e5. doi: 10.1016/j.immuni.2024.06.016.
PMID: 39043185
Resident memory T cells and cancer.
Immunity. 2024 Aug 13;57(8):1734-1751. doi: 10.1016/j.immuni.2024.06.017.
PMID: 39142275
Cancer Immunol Res. 2024 Aug 1;12(8):952-953. doi: 10.1158/2326-6066.CIR-24-0481.
PMID: 38967231
Proc Natl Acad Sci U S A. 2024 Jul 30;121(31):e2320303121. doi: 10.1073/pnas.2320303121.
PMID: 39008691
Sterile production of interferons in the thymus affects T cell repertoire selection.
Sci Immunol. 2024 Jul 26;9(97):eadp1139. doi: 10.1126/sciimmunol.adp1139.
PMID: 39058762
J Immunother Cancer. 2024 Jul 24;12(7):e008959. doi: 10.1136/jitc-2024-008959.
PMID: 39053944
iPSC-derived NK cells expressing high-affinity IgG Fc receptor fusion CD64/16A to mediate flexible, multi-tumor antigen targeting for lymphoma.
Front Immunol. 2024 Jul 19;15:1407567. doi: 10.3389/fimmu.2024.1407567.
PMID: 39100677
Life Sci Alliance. 2024 Jul 18;7(10):e202302516. doi: 10.26508/lsa.202302516.
PMID: 39025525
An exercise in relaxation: right ventricular diastolic function predicts exercise capacity in pulmonary arterial hypertension.
Eur Respir J. 2024 Jul 18;64(1):2401142. doi: 10.1183/13993003.01142-2024.
PMID: 39025515
Regulatory T-cell dysfunction and cutaneous exposure to Staphylococcus aureus underlie eczema in DOCK8 deficiency.
J Allergy Clin Immunol. 2024 Jul;154(1):143-156. doi: 10.1016/j.jaci.2023.12.020.
PMID: 38185418
PD1 blockade improves survival and CD8+ cytotoxic capacity, without increasing inflammation, during normal microbial experience in old mice.
Nat Aging. 2024 Jul;4(7):915-925. doi: 10.1038/s43587-024-00620-4. Epub 2024 Apr 30.
PMID: 38689133
J Heart Lung Transplant. 2024 Jul;43(7):1116-1117. doi: 10.1016/j.healun.2024.03.005
PMID: 38518864
Arterioscler Thromb Vasc Biol. 2024 Jul;44(7):1646-1657. doi: 10.1161/ATVBAHA.124.320797. Epub 2024 May 2.
PMID: 38695172
Circulating KLRG1+ long-lived effector memory T cells retain the flexibility to become tissue resident.
Sci Immunol. 2024 Jun 28;9(96):eadj8356. doi: 10.1126/sciimmunol.adj8356.
PMID: 38941479
iScience. 2024 Jun 17;27(7):110290. doi: 10.1016/j.isci.2024.110290.
PMID: 39045105
bioRxiv [Preprint]. 2024 Jun 12:2024.06.10.598293. doi: 10.1101/2024.06.10.598293.
PMID: 38915668
Nat Aging. 2024 Jun 12. doi: 10.1038/s43587-024-00649-5.
PMID: 38867059
Immunity. 2024 Jun 11;57(6):1184-1186. doi: 10.1016/j.immuni.2024.05.014.
PMID: 38865962
Hemangiosarcoma Cells Promote Conserved Host-derived Hematopoietic Expansion.
Cancer Res Commun. 2024 Jun 11;4(6):1467-1480. doi: 10.1158/2767-9764.CRC-23-0441.
PMID: 38757809
bioRxiv [Preprint]. 2024 Jun 3:2024.05.31.596695. doi: 10.1101/2024.05.31.596695.
PMID: 38895229
Cancer Res Commun. 2024 May 31;4(5):1380-1397. doi: 10.1158/2767-9764.CRC-24-0205.
PMID: 38717149
Nat Immunol. 2024 May 15. doi: 10.1038/s41590-024-01842-9.
PMID: 38750319.
Elife. 2024 May 14;13:RP95481. doi: 10.7554/eLife.95481.
PMID: 38742856
Successful Treatment of Recurrent Clostridioides difficile Infection Using a Novel, Drinkable, Oral Formulation of Fecal Microbiota.
Dig Dis Sci. 2024 May;69(5):1778-1784. doi: 10.1007/s10620-024-08351-7.
PMID: 38457115
Cutting Edge: First Lung Infection Permanently Enlarges Lymph Nodes and Enhances New T Cell Responses.
J Immunol. 2024 Apr 15:ji2400010. doi: 10.4049/jimmunol.2400010.
PMID: 38619284
Short Report: CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation.
bioRxiv [Preprint]. 2024 Apr 10:2024.04.06.588414. doi: 10.1101/2024.04.06.588414.
PMID: 38645184
Peptide targeting improves the delivery and therapeutic index of glucocorticoids to treat rheumatoid arthritis.
J Control Release. 2024 Apr;368:329-343. doi: 10.1016/j.jconrel.2024.02.040.
PMID: 38431094
Profibrotic VEGFR3-Dependent Lymphatic Vessel Growth in Autoimmune Valvular Carditis.
Arterioscler Thromb Vasc Biol. 2024 Apr;44(4):807-821. doi: 10.1161/ATVBAHA.123.320326.
PMID: 38269589
Age-associated accumulation of B cells promotes macrophage inflammation and inhibits lipolysis in adipose tissue during sepsis.
Cell Rep. 2024 Mar 15;43(3):113967. doi: 10.1016/j.celrep.2024.113967.
PMID: 38492219
IL-15 Complex-Induced IL-10 Enhances Plasmodium-specific CD4+ T Follicular Helper Differentiation and Antibody Production.
J Immunol. 2024 Mar 15;212(6):992-1001. doi: 10.4049/jimmunol.2300525.
PMID: 38305633
Mouse Models of Sepsis.
Kannan SK, Kim CY, Heidarian M, Berton RR, Jensen IJ, Griffith TS, Badovinac VP.
Curr Protoc. 2024 Mar;4(3):e997. doi: 10.1002/cpz1.997.
PMID: 38439603
Defining and targeting macrophage heterogeneity in the mammary gland and breast cancer.
Cancer Med. 2024 Feb;13(3):e7053. doi: 10.1002/cam4.7053.
PMID: 38426622
A guide to thymic selection of T cells.
Nat Rev Immunol. 2024 Feb;24(2):103-117. doi: 10.1038/s41577-023-00911-8.
PMID: 37464188
To die or not to die: Gasdermins in intestinal health and disease.
Semin Immunol. 2024 Feb;71:101865. doi: 10.1016/j.smim.2024.101865.
PMID: 38232665
Comparison of mouse models of microbial experience reveals differences in microbial diversity and response to vaccination.
mSphere. 2024 Jan 29:e0065423. doi: 10.1128/msphere.00654-23.
PMID: 38286428
Centrosomal Protein 55 (CEP55) Drives Immune Exclusion and Resistance to Immune Checkpoint Inhibitors in Colorectal Cancer.
Vaccines (Basel). 2024 Jan 8;12(1):63. doi: 10.3390/vaccines12010063.
PMID: 38250876
Treg cell dysfunction and cutaneous exposure to S. aureus underlie eczema in DOCK8 deficiency.
J Allergy Clin Immunol. 2024 Jan 5:S0091-6749(24)00005-8. doi: 10.1016/j.jaci.2023.12.020.
PMID: 38185418
Long- and short-term effects of fecal microbiota transplantation on antibiotic resistance genes: results from a randomized placebo-controlled trial.
Gut Microbes. 2024 Jan-Dec;16(1):2327442. doi: 10.1080/19490976.2024.2327442.
PMID: 38478462
Dysfunctional mucus structure in cystic fibrosis increases vulnerability to colibactin-mediated DNA adducts in the colon mucosa.
Gut Microbes. 2024 Jan-Dec;16(1):2387877. doi: 10.1080/19490976.2024.2387877. Epub 2024 Aug 12.
PMID: 39133871