Immunology Training Grant

The Immunology Training Grant (2T32AI007313) is an NIH-NIAID sponsored (T32) training program.  Funded since 1989, the T32 provides support for outstanding predoctorial trainees to do impactful basic and translational research in Immunology at the University of Minnesota.      

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Former Directors: Tucker LeBien & Marc Jenkins
Current Director: Kristin Hogquist    

 

History    

At the inception, the grant was under the directorship of Dr. Tucker LeBien.  The T32 grant played a key role in the development of the first University of Minnesota graduate program to feature Immunology and to help recruit several new Immunologists which led to the establishment of the multi-departmental Center for Immunology (CFI).  With the establishment of the CFI, the coordination of Immunology research and educational activities was housed in one location, fostering a true collaborative environment.  After the CFI was established Dr. LeBien transferred the directorship of the T32 Training Grant to Dr. Marc Jenkins, who at the time was the co-director of CFI.  Dr. Jenkins continued to successfully foster the grant for over 16 years.  In 2012 Dr. Jenkins passed the directorship of the T32 grant to the current CFI co-director, Dr. Kristin Hogquist.  During its long history, the T32 grant has served as a solid and consistent base of support for the highest quality graduate students studying Immunology.


Preceptors

The T32 Training Grant program has been designed to provide pre-doctoral students with the intellectual and technical skills needed to become highly productive, creative and independent scientists.  To promote the development of these skills, the students are mentored by an outstanding Immunology faculty member.  The preceptors involved in this grant not only have an enthusiam for mentoring but represent a broad range of research areas in Immunology.  The T32 Training Grant is supported by 22 highly productive research preceptors that represent 8 different departments in the Medical School.  Some of the research interests include: Autoimmunity, Signal Transduction, Transplantation, Tumor Immunology, Mutation and Carcinogenesis, T cell Development, Cell Trafficking, Immunologic Tolerance and T cell Migration.

Faculty preceptors for graduate training in immunology

  • Bryce Binstadt | Pediatrics   
    Research Interest: Autoimmunity, Innate immunity
  • Bruce Blazar | Pediatrics    
    Research Interest: Immunobiology of transplantation
  • Paul Bohjanen | Microbiology and Immunology  
    Research Interest: T lymphocyte mRNA stability
  • Michael Farrar | Laboratory Medicine & Pathology    
    Research Interest: Lymphocyte signal transduction and development
  • Brian Fife | Medicine
    Research Interest: Autoimmunity, tumor immunology, immunological tolerance, intravital 2 photon imaging
  • Tanya Freedman | Pharmacology
    Research Interest: Regulation of membrane-proximal signaling in hematopoietic cells, macrophage response due to inflammation
  • Thomas Griffith | Urology    
    Research Interest: TRAIL as a cancer therapeutic and ability of apoptotic cells to influence the immune response
  • Reuben Harris | Biochemistry    
    Research Interest: Mechanisms of mutation in immunity and carcinogenesis
  • Kristin Hogquist | Laboratory Medicine & Pathology    
    Research Interest: T lymphocyte development and selection
  • Ryan Hunter | Microbiology and Immunology
    Research Interest: Host-microbe interactions, microbial community dynamics
  • Stephen Jameson | Laboratory Medicine & Pathology    
    Research Interest: T cell homeostasis, differentiation, trafficking and memory
  • Marc Jenkins | Microbiology and Immunology    
    Research Interest: Helper T lymphocyte biology
  • Alex Khoruts | Medicine    
    Research Interest: Tolerance, autoimmunity, and mucosal immunopathology
  • Dan Knights | Computer Science and BioTechnology Institute
    Research Interest: Bioinformatics and Computational Biology
  • David Masopust | Microbiology and Immunology    
    Research Interest: T cell migration, differentiation, and memory in infection
  • Jeffrey Miller | Medicine    
    Research Interest: Natural killer cell development and cancer
  • Branden Moriarity | Pediatrics  
    Research Interest: Pediatric cancer genetics, Gene-editing, Immunotherapy
  • Daniel Mueller | Medicine    
    Research Interest: T cell tolerance and anergy
  • Christopher Pennell | Laboratory Medicine & Pathology
    Research Interest: Development of DNA based cancer vaccines
  • Erik Peterson | Medicine   
    Research Interest: Leukocyte signaling and development
  • Kaylee Schwertfeger | Laboratory Medicine & Pathology
    Research Interest: Breast cancer cells interaction and microenvironments
  • Yoji Shimizu | Laboratory Medicine & Pathology    
    Research Interest: Leukocyte activation and development
  • Daniel Vallera | Therapeutic Radiology    
    Research Interest: Anti-cancer biologic agents
  • Vaiva Vezys | Microbiology and Immunology    
    Research Interest: T cell responses in autoimmunity and chronic infections


Application Information

Each year the training grant supports up to 6 pre-doctoral students.  A student can remain on the training grant for up to two years. During the time of the fellowship the student is provided with a stipend, tuition, travel and equipment support.

Fellowships are awarded annually based on a competitive process which is decided on by a faculty vote.  Applications are solicited by invitation only, typically in June.  To be eligible for consideration pre-doctoral students must meet the following criteria:

  • Must be a U.S. citizen or permanent resident.
  • Thesis research must be done in 1 of 22 faculty preceptors laboratories.
  • The student must have completed (or be on track to complete their preliminary exam in the current season), but must have at least 12 months remaining towards completion of their PhD.
  • Thesis research must be focused on an Immunological problem.
  • Student must agree to fulfill training requirements: MICA8003MICA8011, participation in RCR training, attending and presenting at Immunology data and journal clubs, attend and present a poster at Immunology retreat.
  • The student will also agree to submit yearly progress reports, ensure that publications are deposited in Pub Med Central, prepare an IDP, and participate in an exit review.

For more information, contact Kris Hogquist at hogqu001@umn.edu.

Current Trainees  

Past Trainees