In response to the COVID-19 pandemic, the University Imaging Centers have implemented mandatory safety protocols. Please visit our sunrise safety protocols page to learn more 



The University Imaging Center's network of facilities offers instrumentation and support for light and electron microscopy, multiplex ion beam imaging, spatial genomics, tissue clearing, in-vivo imaging from subcellular to whole animals, image analysis, visualization, and slide scanning.

UIC Staff is available to assist in experimental design, probe and labeling selection, sample handling, tissue clearing, as well as data analysis, visualization, and interpretation.

In addition to training users to independently operate our instrumentation, the University Imaging Centers also offers several end-to-end research and full sample preparation services.


  • Laser scanning confocal microscopes with multiphoton capabilities (two)
  • Single-photon confocal microscopes (six, three with spectral unmixing)
  • Super-resolution Structured Illumination Microscopy (SIM)
  • Spinning disk confocal microscope
  • Total Internal Reflection Fluorescence (TIRF) Microscope
  • Fluorescent spectral meso-confocal
  • Automated widefield microscopes
  • High-speed ribbon confocal
  • Light Sheet

Also available at UIC facilities

  • Spectral scans
  • Deconvolution
  • High-content widefield and confocal plate imaging
  • FRET (Fluorescence Resonance Energy Transfer)
  • FRAP (Fluorescence Recover After Photobleaching)
  • FLIM (Fluorescence Lifetime Imaging
  • SHG (Second Harmonic Generation) Imaging
  • Multi-channel live cell time-lapse
  • Small animal/bioluminescence / fluorescence (four, on with X-ray)
  • BSL-2 cabinets
  • Phosphor / fluorescence scanners for molecular biology
  • Bioluminescence and fluorescence in-vivo small animal imagers
  • Scanning Electron Microscope (SEM)
  • Transmission Electron Microscope (TEM)
  • microPET/CT
  • Multiplexed Ion Beam Imaging (MIBI)
  • diSPIM light sheet
  • Tissue clearing
  • Large format poster printing
  • 3D printing
  • Brightfield and fluorescence slide scanning.

Using UIC instrumentation

The University Imaging Centers (UIC) is a fee-for-use facility open to investigators and projects of members of the University of Minnesota community as well as external users.

The first step towards gaining access to UIC equipment is to submit a training request.