Faculty

Research Summary

Dr. Pardo leads a research program which seeks to elucidate the functional architecture of the human brain with particular emphasis on how dysfunction within neural networks relates to psychiatric disorders. The multidisciplinary approach (in close collaboration with the Brain Sciences Center, Department of Psychology, Department of Psychiatry, and GRECC) involves methods from cognitive neuroscience, including several imaging modalities, particularly PET and fMRI.His team identified the anterior cingulate cortex as a pivotal locus of cognitive aging in otherwise healthy individuals (Neuroimage. 2007 April 15; 35(3): 1231–1237). They now seek to understand the significance and pathophysiological basis of this finding in the context of systems neuroscience, biochemistry, and animal models. They are also using brain imaging for early diagnosis of the dementias (Alzheimers Dement. 2010 July; 6(4): 326–333). Given the current heterogeneity of psychiatric diagnosis, a developing interest is imaging genetics to identify genotypes with defined psychiatric phenotypes that may lead to improved models of mental disease. For additional information, see the Pardo laboratory website at http://james.psych.umn.edu/.

Clinical Summary

Mood disorders; treatment-resistant; neuroimaging

Bio

After receiving my BA in Psychology from Yale University, I completed my PhD in Clinical Psychology at the University of Minnesota where I was also a postdoctoral student.I am an adult psychologist whose research focuses on identifying novel approaches to treat eating disorders, particularly by targeting the psychological and neurobiological factors that maintain these conditions. I have published close to 200 peer-reviewed articles, with many as first or last author, and have an h-index score of 41. I have given grand rounds and delivered presentations both nationally and internationally at more than 100 conferences.I am the Chair of the Advisory Board at The Emily Program, a national eating disorders treatment program, and I serve on the Editorial Board of the International Journal of Eating Disorders and the Journal of Eating Disorders . I am also an Academy for Eating Disorders Fellow. Within the department, I serve on the Impact and Wellbeing Council and as well as a lead for the Faculty Mentorship Program . In addition, I work as a clinician in our department's Intervention Psychiatry program.

Research Summary

Eating disorders: Specifically treatment outcome, assessment, and diagnosis

Clinical Summary

Eating disorders

Bio

Dr. Polley is originally from Minnesota and completed her Bachelor of Science degree in child psychology from the University of Minnesota and the Institute of Child Development. She then went on to medical school at the University of Minnesota. She completed her adult psychiatry training in a joint program between Sheppard Pratt Hospital and the University of Maryland. Dr. Polley moved to Harvard Medical School to complete her child and adolescent psychiatry fellowship at Boston Children's Hospital. She served as chief fellow during her final year at Harvard and was actively involved in medical education and teaching throughout her training. Dr. Polley is currently working for PrairieCare Medical Group as an outpatient psychiatrist for their child and adolescent programs. She has additional training in substance use disorders and their treatment.

Clinical Summary

Substance Use Disorders; Dual Diagnosis; Psychiatric Crisis Evaluation; Psychodynamic psychotherapy; Motivational Enhancement Therapy

Research Summary

Posttraumatic stress disorder Risk and Resilience Trajectories of posttraumatic psychopathology and adjustment Longitudinal methods Cognitive behavioral interventions

Clinical Summary

Post-traumatic Stress Disorder; Prolonged Exposure Therapy; Cognitive Behavioral Therapy

Bio

Karina Quevedo, PhD, LP, is a tenured Associate Professor in the Department of Psychiatry & Behavioral Sciences. She directs the Health and Emotions in Adolescent Trajectories laboratory (HEAT lab). Dr. Quevedo completed her doctoral graduate training at the University of Minnesota Institute of Child Development (ICD) and her postdoctoral T32 training at the University of Pittsburgh Western Psychiatric Institute and Clinics. She has received a BA in Psychology from the University of Havana, Cuba and an MA in counseling psychology from the University of St. Thomas, MN. Dr. Quevedo is an active faculty member at the Center for Neurobehavioral Development. Her research interests span typical and atypical pathways of emotional development; brain, physiological and hormonal markers of child and adolescent adaptation; long term impact of adverse experience; and adolescent psychopathology. She has further interests in neuromodulation approaches to treatment resistant depression (TRD) and suicide attempts in youth. Dr. Quevedo trains graduate and undergraduate students as both emerging clinicians and scientists and mentors post-doctoral junior scientists.

Research Summary

Typical and Atypical Pathways of Emotional Development: http://www.ncbi.nlm.nih.gov/pubmed/19144221 Brain, Physiological and Hormonal Markers of Child and Adolescent Adaptation: http://www.ncbi.nlm.nih.gov/pubmed/22383860 http://www.ncbi.nlm.nih.gov/pubmed/18037012 http://www.ncbi.nlm.nih.gov/pubmed/20027622 Long Term Impact of Adverse Experience: http://www.ncbi.nlm.nih.gov/pubmed/24552550 http://www.ncbi.nlm.nih.gov/pubmed/16903808 Adolescent Depression and Psychopathology: The neural basis of aspects of self-knowledge, self-understanding and social cognitions are strongly linked to the course and morbidity associated to pediatric depressive disorders and risks for the illness during the adolescent transition. Our laboratory has collected functional magnetic resonance (fmri) data while teens think about- and see themselves while in the scanner. We are currently finishing data processing on three neuroimaging of tasks that tap self-knowledge and social interaction as well as diffusion tension imaging.Graduate students interested in clinical neuroscience are welcomed to contact us at queve001@umn.edufor collaboration in writing of manuscripts, data analyses and learning about how to use fmri to study basic processes of emotion and social cognition.