Faculty
Christopher Staley
, PhD
Assistant Professor, Basic and Translational Research
cmstaley@umn.edu
(612) 625-8831
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Assistant Professor, Basic and Translational Research
Biography
Bio
The intestinal microbiota is a vital organ critical to the development, functioning, and health of the human the host. Our research focus is to characterize how disruptions in this community affect the onset and progression of diseases and conditions e.g., obesity, colorectal cancer, and inflammatory bowel diseases. By applying microbial ecology principles and leveraging next-generation sequencing technologies, our goal is to develop targeted, microbiota-based therapies to improve patient outcomes.
Research Summary
Microbial community dynamics related to obesity and type 2 diabetes Fecal microbiota transplantation therapies Patterns of dysbiosis related to health outcomes Network modeling of microbial communities Personalized microbiota therapeutics Microbiota interactions in solid and non-solid cancers
Education
PhD,
University of South Florida
Major: Biology
Minor: Environmental and Ecological Microbiology
BS,
University of South Florida
Major: Microbiology
Fellowships, Residencies, and Visiting Engagements
Research Associate, Residency
University of Minnesota
Post-doctoral Associate, Residency
University of Minnesota
Honors and Recognition
Microbial and Plant Genomics Institute Travel Award, University of Minnesota
2014
USEPA Scientific and Technological Achievement Award – Level II
2013
Professional Memberships
Masonic Cancer Center, University of Minnesota
BioTechnology Institute, University of Minnesota
American Society for Microbiology
Selected Presentations
Selected Presentations
Rashidi, A., (Author & Presenter), Kaiser, T., (Author), Shields-Cutler, R., (Author), Graiziger, C., (Author), Rehman, T., (Author), Holtan, S. G., (Author), Weisdorf, D. J., (Author), Knights, D. B., (Author), Khoruts, A., (Author), Staley, C. M., (Author)
"Outpatient-to-Inpatient Transition Causes Marked Dysbiosis in Allogeneic Hematopoietic Cell Transplantation Recipients",
Transplantation & Cellular Therapy Meetings,
Center for International Blood & Marrow Transplant Research,
Houston,
Texas,
United States.
February 22, 2019.
Staley, C. M.
"Validation of a Human Microbiota-Associated Mouse Model to Study Obesity",
Research Animal Resources,
University of Minnesota,
November 16, 2018.
Stornetta, A., Kimmell, C., Hamilton, M., Kaiser, T., Staley, C. M., Khoruts, A., Wagner, J., MacMillan, M., Balbo, S.
"Aldehyde Exposure in the Oral Cavity of Subjects with Fanconi Anemia",
Fanconi Anemia Research Fund Symposium,
Newport Beach,
California,
September 27, 2018.
Weiskerger, C., Brandão, J. S., Robinson, C., Staley, C. M., Kleinheinz, G., Nshimyiamana, J. P., Kinzelmen, J., Nevers, M. B., Sadowsky, M. J., Phanikumar, M. S., Whitman, R., Edge, T. A., Piggot, A., Boehm, A., Aslan, A., Badgley, B., Heaney, C., Symonds, E., Solo-Gabriele, H., Fleisher, J., Harwood, J., Yamahara, K., Vogel, L., Jordao, M. L., Avolio, L., Merilainen, P., Pitkanen, T., Ahmed, W., Staley, Z., Klaus, J.
"Effects of a Changing Earth of Microbial Dynamics and Human Health Risks in the Water/Sand Continuum",
International Association for Great Lakes Research 61st Conference on Great Lakes Research,
Toronto,
Canada.
June 18, 2018.
Sadowsky, M., Brown, C., Staley, C. M.
"Use of DNA Sequence Technology to Determine Sources and Sinks of Microbes in Waterways",
International Association for Great Lakes Research 61st Conference on Great Lakes Research,
Toronto,
Canada.
June 18, 2018.
Harwood, V., Ahmed, W., Hamilton, K. A., Lobos, A., Hughes, B., Staley, C. M., Sadowsky, M. J.
"QMRA Links Risk of Gastroenteritis from Viral Pathogens to Microbial Source Tracking Markers in Sewage",
Water Microbioogy Conference,
University of North Carolina,
Chapel Hill,
North Carolina,
May 22, 2018.
Staley, C. M.
"Restoration of Intestinal microbiota Diversity by Encapsulated Fecal Microbiota Transplantation to Treat Clostridium difficile Infection",
Surgical Critical Care Fellowship Program,
University of Minnesota,
March 22, 2018.
Staley, C. M.
"The Role of the Intestinal Microbiota in Human Health Outcomes",
Brown Bag Talk,
University of Minnesota, Medical School, Department of Surgery,
February 23, 2018.
Staley, C. M.
"Changes in the Intestinal Microbial Community Associated with Obesity and Insulin Resistance",
Resident Seminar,
University of Minnesota, Medical School, Department of Surgery,
December 14, 2017.
Sinigalliano, C., Gramer, L., Lee, H. W., Gidley, M., Lopez, J., Staley, C. M., Chun, C., Sadowsky, M., Putman, N., Hendee, J., Rosales, S.
"Drivers of Reef Microbiome Community Structure: Next-Generation Sequencing, Microbial Source Tracking, Gene Flow, and Physical Habitat",
European Coral Reef Symposium,
Oxford,
United Kingdom.
December 13, 2017.
Sadowsky, M. J., Staley, C. M., Khoruts, A.
"Freeze-dried and Encapsulation Microbiota Successfully Cures Recurrent Clostridium difficile Infection",
The Human Miccrobiome: Emerging Themes at the Horizon of the 21st Century,
Bethesda,
Maryland,
August 16, 2017.
Staley, C. M., Romão, D., Ferreira, F., Rodrigues, R., Sabino, R., Veríssimo, C., Wang, P., Brandão, J., Sadowsky, M. J.
"Next-Generation Sequencing and Culture-Based Techniques Offer Complementary Insights into Fungi and Prokaryotes in Beach Sands",
American Society for Microbiology Microbe Meeting,
New Orleans,
Louisiana,
June 01, 2017.
Staley, C. M.
"Evaluation of Structure-Function Relationships in Next-Generation Sequence Data",
PLPA 5999: Plant Pathology Workshop,
University of Minnesota,
April 26, 2017.
Jahansouz, C., Staley, C. M., Xu, H., Hertzel, A., Hahn, W., Krumm, Z., Leslie, D., Bernlohr, D., Sadowsky, M., Khoruts, A., Ikramuddin, S.
"The Vertical Sleeve Gastrectomy is Responsible for Dominant Shifts in Gut Microbiota",
American Society for Metabolic and Bariatric Surgery Obesity Week,
New Orleans,
Louisiana,
October 31, 2016.
Brown, C. M., Staley, C. M., Wang, P., Chun, C. L., Sadowsky, M. J.
"A High-Throughput Sequencing Approach for Determining Sources of Fecal Bacteria in the Lake Superior Watershed",
American Society for Microbiology Microbe Meeting,
Boston,
Massachusetts,
June 16, 2016.
Hall, R., Heine, C., Oh, S., Staley, C. M., Hamilton, M., Khoruts, A., Kelly, C., Brandt, L., Sadowsky, M.
"Workflow for Processing High-Throughput, Single Molecule, Real-Time Sequencing Data, for Analyzing the Microbiome of Patients Undergoing Fecal Microbiota Transplantation",
American Society for Microbiology Microbe Meeting,
Boston,
Massachusetts,
June 16, 2016.
Heiner, C., Oh, S., Hall, R., Staley, C. M., Hamilton, M., Khoruts, A., Kelly, C., Brandt, L., Sadowsky, M.
"WGS SMRT Sequencing of Patient Samples from a Fecal Microbiota Transplant Trial",
American Society for Microbiology Microbe Meeting,
Boston,
Massachusetts,
June 16, 2016.
Pasa-Tolic, L., Ferrieri, A., Ansong, C., Brewer, H., Norbeck, A., Markillie, M., Ferrieri, R., Tringe, S. G., Sadowsky, M., Staley, C. M., Cui, Y., Stacey, G.
"The Dynamic Nature of the Arabidopsis Rhizosphere Microbiota",
American Society for Microbiology Microbe Meeting,
Boston,
Massachusetts,
June 16, 2016.
Staley, C. M., Sadowsky, M. J.
"Regional Similarity and Consistent Patterns of Local Variation in Beach Sand Bacterial Communities throughout the Northern Hemisphere",
American Society for Microbiology Microbe Meeting,
Boston,
Massachusetts,
June 16, 2016.
Pasa-Tolic, L., Ferrieri, A., Ansong, C. K., Brewer, H. M., Norbeck, A. D., Cui, Y., Staley, C. M., Tfaily, M., Chu, R., Shaw, J., Markillie, M. L., Ferrieri, R. A., Tringe, S. G., Sadowsky, M. J., Stacey, G.
"Integrated Omics Reveals Dynamic Nature of the Arabidopsis Rhizosphere Microbiome",
64th Conference on Mass Spectrometry and Allied Topics,
San Antonio,
Texas,
June 05, 2016.
Li, X., Harwood, V. J., Nayak, B., Staley, C. M., Sadowsky, M. J., Weidhaas, J.
"A Customized DNA Microarray for Microbial Source Tracking in Environmental Systems",
2016 Recreational Waters Conference,
New Orleans,
Louisiana,
April 12, 2016.
Ahmed, W., Staley, C. M., Sadowsky, M. J., Gyawali, P., Sidhu, J. S., Beale, D., Toze, S.
"Application of Genetic Markers and Sequencing for the Identification of Fecal Pollution in an Urban River",
18th International Symposium on Health-Related Water Microbiology,
Lisbon,
Portugal.
September 13, 2015.
Solo-Gabriele, H. M., Harwood, V. J., Kay, D., Fujioka, R. S., Sadowsky, M. J., Whitman, R. L., Wither, A., Canica, M., da Fonsec, R. C., Duarte, A., Edge, T. A., Gargaté, M. J., Gunde-cimerman, N., Hagen, F., McLellan, S. L., Silva, A., Babič, M. N., Prada, S., Rodrigues, R., Romão, D., Sabino, R., Samson, R. A., Segal, R., Staley, C. M., Taylor, H. D., Veríssimo, C., Viegas, C., Barroso, H., Brandão, J.
"Beach Sand and the Potential for Infectious Disease Transmission: Observations and Recommendations",
18th International Symposium on Health-Related Water Microbiology,
Lisbon,
Portugal.
September 13, 2015.
Staley, C. M., Gould, T. J., Wang, P., Phillips, J., Cotner, J. B., Sadowsky, M. J.
"Evaluation of Water Sampling Methodologies for Metagenomic Characterization of Bacterial Community Structure",
American Society of Microbiology General Meeting,
New Orleans,
Louisiana,
May 30, 2015.
Fernandez, A. L., Sheaffer, C. C., Sadowsky, M., Wyse, D., Staley, C. M.
"Cover Crop and Fertilizer Effects on Soil Bacterial Community Structure and Function in Organic Farming Systems",
American Society of Agronomy | Crop Science Society of America | Soil Science Society of America International Annual Meeting,
Long Beach,
California,
November 02, 2014.
Staley, C. M., Gould, T. J., Wang, P., Phillips, J., Cotner, J. B., Sadowsky, M. J.
"Species Sorting Dynamics in the Bacterial Community of the Upper Mississippi River are Influenced by Land Use and Sediment Resuspension",
American Society for Microbiology General Meeting,
Boston,
Massachusetts,
May 17, 2014.
Staley, C. M., Unno, T., Gould, T. J., Jarvis, B., Phillips, J., Cotner, J. B., Sadowsky, M. J.
"Relationship Between Land Use and Anthropogenic Factors Influencing Bacterial Community Structure in the Upper Mississippi River",
American Society for Microbiology General Meeting,
Denver,
Colorado,
May 18, 2013.
Young, S., Nayak, B., Staley, C. M., Sadowsky, M. J., Harwood, V. J.
"Characterization of the Microbial Community in Alligator Fecal Samples Using a Metagenomics-Based Approach",
American Society for Microbiology General Meeting,
Denver,
Colorado,
May 18, 2013.
Heisel, T., Podgorski, H., Staley, C. M., Badgley, B., Sadowsky, M. J., Gale, C. A.
"Molecular Strategy To Evaluate the Impact of Fungal Microbiomes on Infant Health",
Pediatric Academic Societies Annual Meeting,
Washington,
District of Columbia,
May 04, 2013.
Schoen, M. E., Staley, C. M., Gordon, K. V., Harwood, V. J.
"Microbial Risk Assessment of Sewage-Impacted Waters: Potential Use of Microbial Source Tracking Assays",
International Society of Exposure Sciences,
Seattle,
Washington,
October 28, 2012.
Harwood, V. J., Gordon, K. V., Staley, C. M.
"Case Studies and Caveats: Microbial Source Tracking In Coastal Waters",
Coastal and Estuarine Research Foundation,
Daytona Beach,
Florida,
November 06, 2011.
Staley, C. M., Harwood, V. J.
"Characterization of Vibrio sinaloensis and Differentiation form Vibrio vulnificus",
Southeastern Branch American Society for Microbiology,
Gainesville,
Florida,
October 20, 2011.
Gordon, K. V., Staley, C. M., Harwood, V. J.
"Persistence of Human-Associated Microbial Markers on a Simulated Tidally-Influenced Estuarine Beach",
Southeastern Branch American Society for Microbiology,
Gainesville,
Florida,
October 20, 2011.
Chase, E., Staley, C. M., Hunting, J., Harwood, V. J.
"Microbial Source Tracking Methods Identify Human and Ruminant Sources of Fecal Pollution in an Ephemeral Florida River",
Southeastern Branch American Society for Microbiology,
Gainesville,
Florida,
October 20, 2011.
Staley, C. M., Harwood, V. J.
"Differential Expression of A Sodium-Phosphate Symporter Gene Among Vibrio vulnificus Strains",
American Society for Microbiology General Meeting,
New Orleans,
Louisiana,
May 21, 2011.
Gordon, K. V., Staley, C. M., Harwood, V. J.
"Persistence of Human-Associated Microbial Markers on a Simulated Tidally-Influenced Estuarine Beach",
American Society for Microbiology General Meeting,
New Orleans,
Louisiana,
May 21, 2011.
Staley, C. M., Harwood, V. J.
"Expression of A Sodium-Dependent Phosphate Cotransporter May Be Linked to Host Colonization in Vibrio vulnificus Strains",
Integrative Biology Seminar Series,
University of South Florida,
Tampa,
Florida,
April 07, 2011.
Harwood, V. J., Gordon, K. V., Staley, C. M.
"Performance Criteria and Field Testing of QPCR Methods for Human-Associated Microbial Source Tracking Markers and Fecal Indicator Bacteria in Fresh and Salt Surface Waters",
EPA National Beach Conference,
Miami,
Florida,
March 15, 2011.
Staley, C. M., Harwood, V. J.
"Analysis of the Relationship of Water Quality and Physical Parameters to Vibrio vulnificus Abundance and Virulence Factor Distribution",
Vibrios in the Environment,
Biloxi,
Mississippi,
November 06, 2010.
Staley, C. M., Reckhow, K., Lukasik, J., Harwood, V. J.
"Assessment of Sources of Human Pathogens and Fecal Contamination in a Florida Freshwater Lake",
American Society for Microbiology General Meeting,
San Diego,
California,
May 23, 2010.
Staley, Z. R., Staley, C. M., Wapnick, C., Harwood, V. J.
"A Weight of Evidence Approach Allows More Accurate Assessment of Sources of Fecal Indicator Bacteria in Surface Waters",
Water Environment Federation TMDL Conference,
Minneapolis,
Minnesota,
August 09, 2009.
Staley, C. M., Fowler, J., Harwood, V. J.
"Analysis of the Distribution of Putative Virulence Markers and Virulence Factors in Vibrio vulnificus Strains",
American Society for Microbiology General Meeting,
Philadelphia,
Pennsylvania,
May 17, 2009.
Staley, C. M., Harwood, V. J.
"Evaluation of a Potential Virulence Marker in Vibrio vulnificus",
Southeastern Branch American Society for Microbiology,
Jacksonville,
Florida,
November 06, 2008.
Wapnick, C. M., Harwood, V. J., Staley, C. M., Singleton, T.
"A Cost-Effective Method for Assessing Fecal Contamination in Florida Tributaries",
StormCon,
Orlando,
Florida,
August 03, 2008.
Staley, C. M., Harwood, V. J.
"A Conserved Hypothetical Protein May Aid in Typing Vibrio vulnificus",
American Society for Microbiology General Meeting,
Boston,
Massachusetts,
June 01, 2008.
Wapnick, C., Staley, C. M.
"A Guide for Assessing Fecal Contamination in Northeast Florida Tributaries",
Southeast Stormwater Association Annual Meeting,
Nashville,
Tennessee,
October 24, 2007.
Staley, C. M., Harwood, V. J.
"Characterization of a Putative Virulence Marker in Vibrio vulnificus Unique to Clinically-Associated Strains",
American Society for Microbiology General Meeting,
Toronto,
Canada.
May 21, 2007.
McQuaig, S., Brownell, M., Staley, C. M., Harwood, V. J.
"Application of Microbial Source Tracking Methods for Human-Associated Sewage at Sites Suspected of Contamination by Compromised wastewater Handling Systems",
American Society for Microbiology General Meeting,
Toronto,
Canada.
May 21, 2007.
Staley, C. M., Harwood, V. J.
"Characterization of a Putative Virulence Marker in Vibrio vulnificus Unique to Clinically-Associated Strains",
Southeastern Branch American Society for Microbiology,
Kennesaw,
Georgia,
November 02, 2006.
Staley, C. M., Harwood, V. J.
"Vibrio vulnificus Populations in Oyster Tissues Using BOX-PCR",
American Society for Microbiology General Meeting,
Orlando,
Florida,
May 21, 2006.
Staley, C. M., Harwood, V. J.
"Analysis of Vibrio vulnificus Population Distribution in Oyster Tissues Using BOX-PCR",
Undergraduate Research Symposium,
University of South Florida,
Tampa,
Florida,
January 01, 2006.
Staley, C. M., Harwood, V. J.
"Analysis of Vibrio vulnificus Populations in Oyster Tissues Using BOX-PCR",
Southeastern Branch American Society for Microbiology,
St. Pete Beach,
Florida,
October 27, 2005.
Contact
Contact
Address
Mayo Mail Code 195420 Delaware St, SE
Minneapolis, MN 55455
Administrative Contact
Kelli Tourand | 612-624-4581 | toura018@umn.edu
Brian Steffen
, PhD, MSCR
Assistant Professor, Division of Computational Health Sciences
steff293@umn.edu
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Assistant Professor, Division of Computational Health Sciences
Biography
Bio
Awards & Recognition
- 2020 Minnesota Cardiovascular Epidemiology and Prevention Training Grant (PI: A. Folsom)
- 2020 University of Minnesota School of Public Health, J.B. Hawley Research Award (PI: Steffen)
- 2014 Multi-Ethnic Study of Atherosclerosis Young Investigator Award
- 2006 American Heart Association, Pre-doctoral Fellowship Award (PI Fellow: Steffen)
Education
- MS, Clinical Research, School of Public Health, University of Minnesota—Twin Cities, MN
- PhD, Physiology, Department of Medical Pharmacology and Physiology, University of Missouri - Columbia, MO
- BS, Organismal Biology, University of Kansas—Lawrence, KS
Research Summary
- Identifying proteomic risk factors of cardiometabolic disease and adverse surgical outcomes
- Conducting Mendelian randomization to determine potential causality between exposure and outcome variables
- Applying these techniques to medicine and surgery to determine whether assessing plasma proteome at pre-op may predict adverse outcomes
Subree Subramanian
, MS, PhD
Professor, Basic and Translational Research
subree@umn.edu
(612) 626-4330
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Professor, Basic and Translational Research
Biography
Bio
Dr. Subramanian completed his postdoctoral fellowship at Stanford University and joined the faculty at the University of Minnesota in 2007. Dr. Subramanian has established an internationally recognized cancer research program focused on deciphering the molecular mechanisms of immune evasion in cancer. His current research focuses on understanding how cancer cells and gut microbiome manipulate the anti-tumor immune response in colorectal cancer. Specifically, Dr. Subramanian's research has shed light on how cancer cells and the gut microbiome collaborate to suppress the immune response in patients with colorectal cancer. Dr. Subramanian and his team have revealed a previously unknown mechanism affecting T cell costimulation in colorectal cancer by identifying the immune suppression mediated by cancer- secreted exosomes. These findings have immense clinical relevance, offering new insights into treating advanced-stage colorectal cancer.
Dr. Subramanian's extensive publication record, including over 120 peer-reviewed articles, attests to his high-quality research and impact. He serves as the section Editor-in-Chief of the journal Vaccines and the Associate section Editor-in-Chief of Cancers. As a co-founder and Chief Scientific Officer of EV Therapeutics Inc., Dr. Subramanian is at the forefront of developing clinical-grade engineered exosomes to treat advanced-stage colorectal cancer patients. Moreover, as a leader in his field, Dr. Subramanian is dedicated to training the next generation of scientists and making a difference in people's lives. Beyond his research and teaching, Dr. Subramanian is committed to giving back to his community, a testament to his dedication to scientific advancement and social responsibility.
ACADEMIC APPOINTMENTS:
- Professor, Department of Surgery
- Member, Masonic Cancer Center
- Member, Center for Immunology
- Senior Graduate faculty, Microbiology, Immunology and Cancer Biology (MICaB) Ph.D. Graduate Program
- Senior Graduate faculty, Molecular Pharmacology and Therapeutics (MPaT) Ph.D. Graduate Program
- Senior Graduate faculty, Bioinformatics and Computational Biology (BICB) Ph.D. Graduate Program
- Director, Resident Research Enrichment Program, Department of Surgery
- Co-leader, Gastrointestinal Cancer Translational Working Group, Masonic Cancer Center
- Faculty Director and Mentor, Proposal Preparation Program, Medical School
PUBLICATIONS
Recent publications:
- Zhao X, Yuan C, Wangmo D, Subramanian S. Tumor-secreted extracellular vesicles regulate T-cell costimulation and can be manipulated to induce tumor-specific T-cell responses. Gastroenterology 2021 161: 560-574
- Wangmo D, Premsrirut PK, Yuan C, Morris WS, Zhao X and Subramanian S. Loss of ACKR4 in tumor cells dysregulates dendritic cell migration to tumor-draining lymph nodes and T-cell priming. Cancers 2021. 7;13(19):5021.
- Nair, AA Tang X, Thompson KJ, Kalari KR, Subramanian S. MicroRNA response elements frequency identifies dysregulation of MAPK signaling in triple-negative breast cancer. Doi: http://dx.doi.org/10.1101/817098. iScience 2020 23(6):101249
- Yuan C, Graham M, Subramanian S. Mucosal Microbiota and Metabolome along the Intestinal Tract Reveal a Location-Specific Relationship. mSystems 2020 5(3):e00055-20 5. Zhao X, Kassaye B, Wangmo D, Lou E, Subramanian S. Chemotherapy but Not the Tumor Draining Lymph Nodes Determine the Immunotherapy Response in Secondary Tumors. iScience 2020 23(5):101056
Contact
Contact
Address
Department of Surgery420 Delaware St SE MMC 195
Minneapolis, MN 55455
Administrative Contact
Kelli Tourand | 612-624-4581 | toura018@umn.edu
Thomas Suszynski
, MD, PhD
Assistant Professor, Division of Plastic and Reconstructive Surgery
susz0003@umn.edu
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Assistant Professor, Division of Plastic and Reconstructive Surgery
Email:
susz0003@umn.edu
Biography
Bio
My primary focus is to provide the highest-quality and world-class patient care as well as to contribute to our field through advances in cutting-edge surgical techniques, therapeutics, devices, and tissue engineering.
Research Summary
Regenerative medicine and tissue engineering Targeted oxygen delivery with therapeutics and devices Bioengineered soft tissue and bone flap design/fabrication for the replacement of diseased or injured tissue
Contact
Contact
Address
7-105 NHHMinneapolis, MN 55455
Administrative Contact
Email: PRSdivision@umn.edu
Phone: 612-625-1188
Fax: 612-624-4441
Maria Evasovich Swenson
, MD
Associate Professor, Division of Surgical Oncology
evaso001@umn.edu
(612) 625-2991
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Associate Professor, Division of Surgical Oncology
Biography
Research Summary
Thyroid Cancers Head & Neck Paraganglioma Hyperparathyroidism
Clinical Summary
Endocrine surgery (thyroid, parathyroid, adrenal); Head and neck cancer surgery; Melanoma; Surgical oncology
Education
MS,
University of Akron
MD,
Medical College of Georgia
BS,
University of Pittsburgh
Major: Pharmacy
Fellowships, Residencies, and Visiting Engagements
Head and Neck Surgery Fellowship,
Memorial Sloan Kettering Cancer Center
General Surgery Residency ,
Akron General Medical Center
Surgical Critical Care Fellowship,
University of Connecticut
Internship,
Akron General Medical Center
Honors and Recognition
Recognized as 2023 Top Doctor by Mpls.St.Paul Magazine
2023
Contact
Christopher Tignanelli
, MD, MS, MBA
Associate Professor, Division of Critical Care & Acute Care Surgery
ctignane@umn.edu
(612) 625-7911
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Associate Professor, Division of Critical Care & Acute Care Surgery
Co-Director, Clinical Quality, Outcomes, Discovery and Evaluation (CQODE)
Associate Dean for Data Science
Biography
Bio
I wholeheartedly enjoy caring for patients with critical illness and emergency surgical conditions. I aim to provide high-quality, evidence-based emergency surgical and critical care to those in need. I treat every patient like I would my own family member. Dr. Tignanelli is an Acute Care Surgeon at the University of Minnesota, providing trauma, emergency surgery, critical care, and ECMO care for critically ill patients. He is triple board-certified in General Surgery, Surgical Critical Care, and Clinical Informatics. His research lab, MNCCORE, includes over 30 researchers developing and deploying informatics-based tools to improve the delivery of healthcare within and beyond the University of Minnesota system. His research focuses on the development and validation of machine learning and AI-enabled decision support systems, as well as the implementation, user-centered design, and scaling of interoperable clinical decision support tools.
Dr. Tignanelli is a tenured Associate Professor of Surgery in the Division of Acute Care Surgery at the University of Minnesota. Within the University of Minnesota, Dr. Tignanelli is also the Associate Dean for Data Science, co-Director for UMN’s Program for Clinical Artificial Intelligence, and co-Director for UMN’s Quality Outcomes, Discovery and Evaluation Core, which oversees the UMN’s clinical data repository. He has published over 125 papers, and his research program focuses on the implementation of an evaluation of AI-enabled and non-AI-based clinical decision support systems into practice with the goal of improving the delivery of evidence-based care. His research program has received $29 million in direct funding from the Gates Foundation, NIH, AHRQ, and the Henry M Jackson Foundation for the Advancement of Military Medicine at the principal investigator or director level.
Research Summary
Quality Improvement Patient Safety Trauma Systems Research Surgical Outcomes
Clinical Summary
Trauma, Surgical Critical Care, ECMO, Emergency general surgery
Education
MS (Clinical Research),
University of Minnesota Twin Cities
MD,
University of Medicine and Dentistry of New Jersey
BS with High Honors,
The College of William and Mary
Fellowships, Residencies, and Visiting Engagements
Surgical Critical Care Fellowship, Fellowship
University of Michigan
General Surgery Resident, Residency
University of North Carolina
T-32 Research Fellowship, Fellowship
Laboratory of Jen Jen Yeh, MD UNC
General Surgery Residency, Residency
University of North Carolina (UNC)
General Surgery Intern, Internship
University of North Carolina (UNC)
Licensures and Certifications
Board Certified in Surgical Critical Care- 2019,
Board Certified in Clinical Informatics - 2020,
Pediatric Advanced Life Support (PALS),
Minnesota Medical Board License,
Licensure/Certification Number: #62128
North Carolina Medical Board,
Michigan Medical Board,
Board Certified in General Surgery Certificate,
Licensure/Certification Number: #062069
Fundamentals of Laparoscopic Surgery,
Advanced Cardiovascular Life Support,
Advanced Trauma Life Support,
Honors and Recognition
Healthcare Heroes: Health Entrepreneur, Minneapolis/St. Paul Magazine- 2021
2021
Top Doctors: Rising Stars, Minneapolis/St. Paul Magazine - 2020
2020
Academic Surgical Congress Grant Writing Workshop, "2019 Annual Meeting", Houston, TX - 2019
2019
Best Paper Competition, Minnesota Surgical Society - 2019
2019
Department of Surgery Research Day Award, University of Minnesota Twin Cities
2018
2017 TQIP Annual Scientific Meeting Performance Improvement Abstract Award, 2017 TQIP Annual Scientific Meeting and Training
2017
Excellence in Research Award, 2017 Surgical Critical Care Program Director Society (SCCPDS)
2017
Variability in Management of Blunt Liver Trauma and Contribution of Level of ACS-COT Verification Status on Mortality, Michigan State Committee on Trauma Resident Paper Competition
2017
Best AAS Overall Manuscript Submission by an AAS Resident or Fellow, 2017 ASC National Meeting
2017
Herbert J. Proctor Award for Excellence in Surgical Research, University of North Carolina
2015
John William Pope Clinical Fellowship, University of North Carolina
2014
American Pancreatic Association Young Investigator Travel Award, University of North Carolina
2013
Runner-up, Best Oral Presentation, 38th Annual Lineberger Postdoc Faculty Research Day
2013
National Cancer Education Summer Research Fellowship Program Award, UMDNJ - New Jersey Medical School
2006
NIH-NCI: Cancer Education Grant, UMDNJ - New Jersey Medical School
2006
Professional Memberships
Eastern Association for the Surgery of Trauma, Quality, Safety, and Outcomes Committee Member
2019-2019
Eastern Association for the Surgery of Trauma
2018-2018
American Medical Informatics Association, 2019 Informatics Summit-Manuscript Reviewer
2018-2018
Surgical Infection Society
2017-2017
Shock Society
2017-2017
Surgical Outcomes Club
2017-2017
American College of Surgeons
2012-2016
Association for Academic Surgery
2012-2016
Society of Critical Care Medicine
2016-2016
Ben Rush Surgical Society
2009-2009
Selected Presentations
Selected Presentations
Purcell, L., Tignanelli, C. J., Maine, R., Charles, A. G.
"Racial and Sex Differences in End of Life Decision Making in Critically Ill Surgical Patients in the Intensive Care Unit",
American College of Surgeons 2018 Clinical Congress,
Boston,
Massachusetts,
October 01, 2018.
Tignanelli, C. J., Hemmila, M. R., Rogers, M., Raghavendran, K.
"Independent Risk Factors for Acute Respiratory Distress Syndrome after Trauma",
The American College of Surgeons (ACS) 2018 Annual Meeting,
Boston,
Massachusetts,
October 01, 2018.
Oliphant, B. W., Tignanelli, C. J., Napolitano, L. M., Goulet, J. A., Hemmila, M. R.
"ACS_COT Verification Level Affects Trauma Center Management of Pelvic Ring Injuries and Patient Mortality",
American Association for the Surgery of Trauma (Plenary, AAST) 2018 Annual Meeting,
San Diego,
California,
September 01, 2018.
Tignanelli, C. J., Adzemovic, T., Murray, T., Ottosen, J., Iyegha, P., Napolitano, L. M., Hemmila, M. R., Gipson, J.
"Should They Stay or Should They Go? Who Benefits from Interfacility Transfer to a Higher Level Trauma Center Following Initial Presentation from a Lower Level Trauma Center",
American Association for the Surgery of Trauma (Plenary, AAST) 2018 Annual Meeting,
San Diego,
California,
September 01, 2018.
Tignanelli, C. J.
"Geriatric Trauma Morbidity, Mortality, and Quality Improvement",
2018 University of Minnesota Health Geriatric Trauma Conference,
Crowne Plaza West Hotel,
Minneapolis,
Minnesota,
May 01, 2018.
Tignanelli, C. J.
"Epidemiology and Evolving Public Health Impact Related to Pre-Injury Controlled Substance Use",
University of Minnesota School of Public Health,
Minneapolis,
Minnesota,
April 01, 2018.
Tignanelli, C. J., Sheetz, K. H., Park, P. K., Napolitano, L. M., Cooke, C., Cherry-Bukowiec, J. R.
"Underutilization of ICU Nutrition Consultation is Associated with Increased Mortality",
Society of Critical Care Medicine (SCCM) Annual Congress,
San Antonio,
Texas,
February 01, 2018.
Tignanelli, C. J.
"Variability in Management of Blunt Liver Trauma and Contribution of Level of ACS-COT Verification Status on Mortality",
American College of Surgeons, Region 5 Trauma Competition,
Madison,
Wisconsin,
November 01, 2017.
Gipson, J., R. R., Tignanelli, C. J., Thorson, M., West, M., Reicks, P.
"Impact of Implementation of an Institutional Guideline for VTE Prophylaxis Process of Care in Patients with Severe Trauma Brain Injury (TBI)",
2017 TQIP Annual Scientific Meeting and Training,
Chicago,
Illinois,
November 01, 2017.
Tignanelli, C. J.
"National Outcomes in Lung Transplantation",
University of Minnesota ECMO Symposium: Advancement Management of the Failing Lung of Heart,
Commons Hotel,
Minneapolis,
Minnesota,
October 01, 2017.
Tignanelli, C. J.
"Variability in Management of Blunt Liver Trauma and Contribution of Level of ACS-COT Verification Status on Mortality",
American Association for the Surgery of Trauma (Plenary, AAST) Annual Meeting,
Baltimore,
Maryland,
September 01, 2017.
Tignanelli, C. J.
"Compliance with ACS-COT Recommended Criteria for Full Trauma Team Activation and Association with Undertriage Deaths",
American Association for the Surgery of Trauma (Plenary, AAST) Annual Meeting,
Baltimore,
Maryland,
September 01, 2017.
Tignanelli, C. J.
"Variability in Management of Blunt Liver Trauma and Contribution of Level of ACS-COT Verification Status on Mortality",
American College of Surgeons/Committee Annual Meeting - Michigan Chapter,
Boyne Falls,
Michigan,
May 01, 2017.
Tignanelli, C. J.
"Compliance with ACS-COT Recommended Criteria for Full Trauma Team Activation and Association with Undertriage Deaths",
MTQIP Publications Committee Update,
Michigan Trauma Quality Improvement Meeting,
Boyne Falls,
Michigan,
May 01, 2017.
Tignanelli, C. J.
"Variability in Management of Blunt Liver Trauma and Contribution of Level of ACS-COT Verification Status on Mortality",
MTQIP Publications Committee Update,
Michigan Trauma Quality Improvement Meeting,
Boyne Falls,
Michigan,
May 01, 2017.
Tignanelli, C. J.
"A Performance Comparison of an Inexpensive, Homemade Central Line Simulator to Commercial Models (Presented by Dr. Brown, co-first author)",
Academic Surgical Congress National Meeting,
Las Vegas,
Nevada,
February 01, 2017.
Tignanelli, C. J.
"Interdisciplinary Morbidity and Mortality Conference, A Method for System-Wide Improvement",
Academic Surgical Congress National Meeting,
Las Vegas,
Nevada,
February 01, 2017.
Tignanelli, C. J.
"Adaptive Response of Pancreatic Cancer to Single Agent Kinase Inhibitor Therapies",
Research Day: University of North Carolina,
Chapel Hill,
North Carolina,
May 01, 2016.
Tignanelli, C. J.
"Pasireotide for the Prevention of Pancreatic Fistula Formation",
General Surgery Grand Rounds,
University of North Carolina,
Chapel Hill,
North Carolina,
March 01, 2016.
Tignanelli, C. J.
"Enhanced Recovery After Surgery at UNC",
Multidisciplinary FI Medicine/Surgery Conference,
University of North Carolina,
Chapel Hill,
North Carolina,
February 01, 2016.
Tignanelli, C. J.
"Is There a Role for Tranexamic Acid (TXA) in Trauma?",
General Surgery Grand Rounds,
University of North Carolina,
Chapel Hill,
North Carolina,
December 01, 2015.
Tignanelli, C. J.
"Adaptive Response of Pancreatic Cancer to Single Agent Kinase Inhibitor Therapies",
Society of Surgical Oncology Annual Cancer Symposium,
Houston,
Texas,
March 01, 2015.
Tignanelli, C. J.
"P13K and Pan-ErbB Inhibition Overcomes ErbB Cross-Talk in Pancreatic Ductal Adenocarcinoma",
Academic Surgical Congress National Meeting,
Las Vegas,
Nevada,
February 01, 2015.
Tignanelli, C. J.
"Enhanced Recovery After Surgery",
Multidisciplinary GI Medicine/Surgery Conference,
University of North Carolina,
Chapel Hill,
North Carolina,
November 01, 2014.
Tignanelli, C. J.
"A Rational Approach for Combination Therapy Selection in Pancreatic Cancer",
American College of Surgeons Annual Meeting,
San Francisco,
California,
October 01, 2014.
Tignanelli, C. J.
"Benzodiazepine Verses Nonbenzodiazepine-Based Sedation for Mechanically Ventilated, Critically Ill Adults",
General Surgery Grand Rounds,
University of North Carolina,
Chapel Hill,
North Carolina,
October 01, 2014.
Tignanelli, C. J.
"A Rational Approach for Combination Therapy Selection in Pancreatic Cancer",
General Grand Rounds,
University of North California,
Chapel Hill,
North Carolina,
May 01, 2014.
Tignanelli, C. J.
"Multiplexed Kinase Inhibitor Beads Identify Multiple Pathways of Resistance to P13K Inhibition Facilitating the Rational Selection of Novel Combination Therapies in Pancreatic Cancer",
AACR Pancreatic Cancer: Innovations in Research and Treatment,
New Orleans,
Louisiana,
May 01, 2014.
Tignanelli, C. J.
"Resistance to P13K Inhibition in Pancreatic Cancer is Mediated through the ErbB Pathway",
Translational Medicine Symposium,
Chapel Hill,
North Carolina,
April 01, 2014.
Tignanelli, C. J.
"Resistance to P13K Inhibition in Pancreatic Cancer is Mediated through the ErbB Pathway",
Society of Surgical Oncology Annual Cancer Symposium,
Pheonix,
Arizona,
March 01, 2014.
Tignanelli, C. J.
"Method for High Sensitivity KRAS Mutation Detection Circulating Tumor Cells (CTCs)",
Academic Surgical Congress,
San Diego,
California,
February 01, 2014.
Tignanelli, C. J.
"KRAS and P13K Mutation Frequencies in Patient Derived Xenograft (PDX) Models of Pancreatic and Metastatic Colorectal cancer (mCRC) are reflective of patient tumors and stable across passages",
Southeastern Surgical Annual Scientific Meeting,
Savannah,
Georgia,
February 01, 2014.
Tignanelli, C. J.
"Circulating Tumor Cells (CTCs) as an Early Biomarker of Treatment Response in Pancreatic Ductal Adenocarcinoma (PDAC)",
American Pancreatic Association Annual Meeting,
Miami,
Florida,
November 01, 2013.
Tignanelli, C. J.
"The P13K inhibitor BKM120 Inhibits Growth of Pancreatic Ductal Adenocarcinoma (PDAC) in Vitro and in Vivo",
American College of Surgeons Annual Meeting,
Washington,
District of Columbia,
October 01, 2013.
Tignanelli, C. J., Torphy, R. J., Moffitt, R., Soper, S. A., Yeh, J. J.
"Circulating Tumor Cells as a Biomarker of Response to Treatment in Patient Derived Xenograft Mouse Models of Pancreatic Adenocarcinoma",
Journal of the American College of Surgeons 2013,
September 01, 2013.
Tignanelli, C. J., Herrera, S. G., Torphy, R. J., Yeh, J. J.
"The PI3K Inhibitor BKM120 Inhibits Growth of Pancreatic Ductal Adenocarcinoma in Vitro and in Vivo",
Journal of the American College of Surgeons 2013,
September 01, 2013.
Tignanelli, C. J.
"A Rational Approach for Combination Therapy Selection in Pancreatic Ductal Adenocarcinoma",
38th Annual Lineberger Postdoc-Faculty Research Day,
Chapel Hill,
North Carolina,
September 01, 2013.
Tignanelli, C. J.
"Circulating Tumor Cells as a Biomarker of Treatment Response in Pancreatic Ductal Adenocarcinoma",
Center for Gastrointestinal Biology and Disease Annual Scientific Retreat,
Chapel Hill,
North Carolina,
June 01, 2013.
Tignanelli, C. J.
"BKM120, a Potential Therapy in Pancreatic Cancer",
Annual Womack Society Meeting: University of North Carolina,
Chapel Hill,
North Carolina,
May 01, 2013.
Tignanelli, C. J.
"Isolation of Circulating Tumor Cells from Patient Derived Xenograft Mouse Models of Pancreatic Cancer",
American Surgical Congress National Meeting,
New Orleans,
Louisiana,
February 01, 2013.
Tignanelli, C. J.
"Circulating Tumor Cells as Biomarkers of Response in Patient Derived Xenografts of Pancreatic Cancer",
Center for Gastrointestinal Biology and Disease Research Competition,
Chapel Hill,
North Carolina,
October 01, 2012.
Tignanelli, C. J.
"Our Experience with Single Incision Laparoscopic Cholecystectomy",
Annual Womack Society Meeting,
University of North Carolina,
Chapel Hill,
North Carolina,
June 01, 2010.
Tignanelli, C. J.
"Isolation of Mutations in MRE11 Gene to Enhance the ATM Checkpoint Pathway",
National Cancer Education Research Forum: Rutgers New Jersey Medical School,
Newark,
New Jersey,
August 01, 2006.
Tignanelli, C. J.
"The Effect of Residual Ca2+ on the Stochastic Gating of Ca2+ -Regulated Ca2+ Channel Models",
Biophysical Society Annual Meeting,
Baltimore,
Maryland,
February 01, 2004.
Contact
Contact
Address
MMC 195420 Delaware St. SE
Minneapolis, MN, 55455
Administrative Contact
(Non-Research) Keara Carpenter | carpe803@umn.edu
Research Scheduling Contact:
(Research) Andrea Lee| leex7731@umn.edu
Todd Tuttle
, MD, MS
Professor, Division of Surgical Oncology
tuttl006@umn.edu
(612) 625-2991
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Professor, Division of Surgical Oncology
Vice-Chair of Global Surgery and Disparities Program
Regis Chair for Breast Cancer Research
Biography
Research Summary
Outcomes after breast cancer treatment Outcomes after cytoreductive surgery and hyperthermic intraperitoneal Surgical outcomes among Native Americans Breast cancer outcomes in Central America
Clinical Summary
Specialties: Surgical oncology, Gastrointestinal cancer, Breast cancer, Melanoma, Sarcoma Interests: Surgical oncology; Gastrointestinal cancer; Breast cancer; Melanoma; Sarcoma; Cancer care in Central America
Education
MD,
Johns Hopkins University School of Medicine
MS,
University of Minnesota School of Public Health
BS,
Creighton University
Fellowships, Residencies, and Visiting Engagements
Surgical Intern and Resident,
The Medical College of Virginia
Surgical Research Fellow,
The Medical College of Virginia
Surgical Resident,
The Medical College of Virginia
Administrative Chief Resident,
The Medical College of Virginia
Surgical Oncology Fellow, MD,
Anderson Cancer Center
Research Fellowship, MD,
Anderson Cancer Center
Honors and Recognition
Recognized as 2023 Top Doctor by Mpls.St.Paul Magazine
2023
Contact
Rochus Voeller
, MD
Associate Professor, Division of Cardiothoracic Surgery
voel0019@umn.edu
(612) 625-3902
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Associate Professor, Division of Cardiothoracic Surgery
Email:
voel0019@umn.edu
Office Phone:
Affiliation:
Division of Cardiothoracic Surgery
Biography
Clinical Summary
Minimally invasive mitral valve repairs; Minimally invasive valve surgery; Aortic surgery; Coronary artery bypass grafting; Surgical treatment of atrial fibrillation; Surgical management of endocarditis; Complex redo heart surgeries; Heart transplantation; Mechanical circulatory assist devices
Education
MD,
University of Minnesota, School of Medicine
BS,
University of Minnesota, College of Biological Sciences
Fellowships, Residencies, and Visiting Engagements
Cardiothoracic Surgery Fellowship, Fellowship
Washington University School of Medicine
Chief Residency in General Surgery, Residency
Washington University School of Medicine
Cardiothoracic Surgery Fellowship Early Specialization Program, Fellowship
Washington University School of Medicine
Residency in General Surgery, Residency
Washington University School of Medicine
Cardiothoracic Surgery Research Fellowship, Fellowship
Washington University School of Medicine
Residency in General Surgery, Residency
Washington University School of Medicine
Internship in General Surgery, Internship
Washington University School of Medicine
Licensures and Certifications
SAGES Fundamentals of Laparoscopic Surgery Program Certificate,
Licensure/Certification Number: #17927181928
Missouri State Medical License,
Licensure/Certification Number: #2005032739
American Board of Thoracic Surgery,
Licensure/Certification Number: #7992
Minnesota State Medical License,
Licensure/Certification Number: #55496
American Board of Surgery,
Licensure/Certification Number: #56297
Honors and Recognition
J Maxwell Chamberlain Memorial Paper for Congenital Heart Surgery, Society of Thoracic Surgeons
2011
Case Medical Scholarship
2001
Life Sciences Summer Undergraduate Research Fellowship
2000
Dean's List
1999
Magna cum laude in Biochemistry
1999
Professional Memberships
The Society of Thoracic Surgeons
Selected Presentations
Selected Presentations
Voeller, R. K.
"Minimally Invasive Aortic Valve Repair",
Altru Health Virtual Grand Rounds,
Altru Health Systems,
Minnesota,
March 09, 2022.
Voeller, R. K.
" An Update in AI Diagnosis, 2020 AHA/ACC Guidelines & Treatment Options",
Aortic Insufficiency in 2021,
HAART Aortic Valve Repair Technologies,
Minnesota,
May 25, 2021.
Voeller, R. K.
"Minimally Invasive Cardiac Surgery",
Rotary Club of Edina,
Edina,
Minnesota,
April 29, 2021.
Voeller, R. K., (Author)
"Surgical Mitral Valve Repair",
Matters of the Heart 2021,
University of Minnesota,
Minneapolis,
Minnesota,
April 23, 2021.
Voeller, R. K.
"Minimally Invasive Mitral Valve Repair",
Altru Health Virtual Grand Rounds,
Altru Health Systems,
Minnesota,
February 10, 2021.
Voeller, R. K., Maniar, H. S., Aziz, A., Ufere, N. N., Tagger, A. K., Bernabe Jr., N., Cupps, B. P., Moon, M. R.
"Altered right ventricular strain and right atrial function in mild versus severe right ventricular pressure overload",
International Conference of the Cardiovascular System Dynamics Society,
Fukuoka,
Japan.
September 01, 2010.
Lee, A. M., Voeller, R. K., Bailey, M. S., Schuessler, R. B., Damiano Jr, R. J.
"The effect of paroxysmal atrial fibrillation and the Cox maze procedure on left atrial function",
Heart Rhythm Society ,
Denver,
Colorado,
United States.
May 01, 2010.
Voeller, R. K., Epstein, D. J., Guthrie, T. J., Gandhi, S. K., Canter , C. E., Huddleston , C. B.
"Trends in the indications and survival in pediatric heart transplants: a 24-year single-center experience in 307 patients",
Society of Thoracic Surgeons,
San Diego,
California,
United States.
January 01, 2010.
Lee, A. M., Voeller, R. K., Bailey, M. S., Schuessler, R. B., Damiano Jr, R. J.
"The effect of paroxysmal atrial fibrillation and the Cox maze procedure on left atrial function",
International Society for Minimally Invasive Cardiothoracic Surgery,
San Francisco,
California,
United States.
June 01, 2009.
Voeller, R. K., Zierer, A., Sakamoto, S., Lall, S. C., Schuessler, R. B., Damiano Jr , R. J.
"Performance of a novel bipolar radiofrequency ablation device Synergy on the beating heart: a chronic porcine study",
International Society for Minimally Invasive Cardiothoracic Surgery,
Boston,
Massachusetts,
United States.
June 01, 2008.
Voeller, R. K., Zierer, A., Sakamoto, S., Lall , S. C., Schuessler , R. B., Damiano Jr , R. J.
"Performance of a novel bipolar radiofrequency ablation device Synergy™ on the beating heart: a chronic porcine study",
Boston Atrial Fibrillation Symposium,
Boston,
Massachusetts,
United States.
January 01, 2008.
Voeller, R. K.
"Characterization of global and regional left atrial function in normal humans and following atrial fibrillation ablation",
Boston Atrial Fibrillation Symposium,
Boston,
Massachusetts,
United States.
January 01, 2008.
Lall, S. C., Sakomoto, S., Foyil, K. V., Voeller, R. K., Boineau, J. P., Schuessler, R. B., Damiano Jr, R. J.
"Acute effects of surgical ablation procedures on atrial autonomic innervation",
American Heart Association,
Orlando,
Florida,
United States.
November 01, 2007.
Lall, S. C., Foyil, K. V., Sakamoto, S., Voeller, R. K., Schuessler, R. B., Damiano Jr , R. J.
"Pulmonary vein isolation and Cox-Maze IV only partially denervates the atria",
Western Thoracic Surgical Association,
Santa Ana Pueblo,
New Mexico,
United States.
June 01, 2007.
Zierer, A., Voeller, R. K., Kouchoukos, N. T., Damiano Jr., R. J., Moon, M. R.
"Fate of the residual aorta following repair of acute Type A aortic dissection.",
International Congress of the European Society for Cardiovascular Surgery,
Venice,
Italy.
May 01, 2007.
Voeller, R. K., Bailey, M. S., Zierer, A., Lall, S. C., Sakamoto, S., Aubuchon, K., Moon, M. R., Schuessler, R. B., Damiano Jr , R. J.
"Surgical outcomes following the Cox-Maze procedure: the importance of isolating the posterior left atrium",
American Association for Thoracic Surgery,
Washington,
District of Columbia,
United States.
May 01, 2007.
Zierer, A., Voeller, R. K., Hill , K. E., Kouchoukos, N. T., Damiano Jr, R. J., Moon, M. R.
"Aortic enlargement and late reoperation following repair of acute Type A aortic dissection",
Society of Thoracic Surgeons,
San Diego,
California,
United States.
January 01, 2007.
Al-Dadah, A. S., Zierer, A., Voeller, R. K., Schuessler, R. B., Damiano Jr, R. J., Lawton, J. S.
"Diazoxide prevents myocyte swelling and reduced contractility secondary to ischemic stress: a potential role in myocyte volume regulation?",
American College of Surgeons,
Chicago,
Illinois,
United States.
October 01, 2006.
Zierer, A., Melby, S. J., Voeller, R. K., Al-Dadah, A. S., Pasque, M. K., Guthrie, T. J., Ewald, G. A., Moazami, N.
"The significance of neurological complications in heart transplant recipients",
World Transplant Congress,
Boston,
Massachusetts,
United States.
July 01, 2006.
Voeller, R. K., Zierer, A., Al-Dadaj, A. S., Wagner , J., Brockmeier, D., Moazami, N.
"The use of vasopressin in the hemodynamic management of solid organ donors is safe",
World Transplant Congress,
Boston,
Massachusetts,
United States.
July 01, 2006.
Melby, S. J., Zierer , A., Lall , S. C., Voeller, R. K., Bailey, M. S., Damiano Jr, R. J.
"Wide variations in energy delivery using an impedance controlled algorithm in bipolar radiofrequency ablation: evidence against fixed time ablation",
International Society for Minimally Invasive Cardiothoracic Surgery,
San Francisco,
California,
United States.
June 01, 2006.
Voeller, R. K., Melby, S. J., Lee, A. M., Lubahn, J. G., Al-Dadah, A. S., Schuessler, R. B., Damiano Jr, R. J.
"A new method of non-invasive measurement of left atrial function after the Cox-Maze procedure",
International Society for Minimally Invasive Cardiothoracic Surgery,
San Francisco,
California,
United States.
June 01, 2006.
Lall, S. C., Melby, S. J., Voeller, R. K., Zierer , A., Bailey , M. S., Guthrie , T. J., Moon , M. R., Damiano Jr , R. J.
"The impact of ablation technology on surgical outcomes following the Cox Maze procedure: a propensity analysis",
American Association for Thoracic Surgery,
Philadelphia,
Pennsylvania,
United States.
May 01, 2006.
Melby, S. J., Zierer , A., Voeller, R. K., Lall , S. C., Bailey , M. S., Moon , M. R., Damiano Jr, R. J.
"A new era in the surgical treatment of atrial fibrillation: the impact of ablation technology and lesion set on procedural efficacy",
American Surgical Association,
Boston,
Massachusetts,
United States.
April 01, 2006.
Zierer, A., Melby, S. J., Voeller, R. K., Al-Dadah, A. S., Ewald, G. A., Skelton, K., Guthrie, T. J., Moazami, N.
"Late drive-line infections: the Achilles’ heel of prolonged LVAD support.",
International Society for Heart and Lung Transplantation,
Madrid,
Spain.
April 01, 2006.
Voeller, R. K., Peterson, A. J., Simon, J. A.
"Mutational analysis of the SPM domain in Drosophila melanogaster",
College of Biological Sciences Honors Program Poster Symposium,
Undergraduate Research Opportunities Program, University of Minnesota,
Twin Cities ,
Minnesota,
United States.
June 01, 1999.
Rodefer, J. S., Campbell, U. C., Cosgrove, K. P., Voeller, R. K., Carroll, M. E.
"Effects of naltrexone treatment on oral self-administration of ethanol, phencyclidine, and saccharin in rhesus monkeys using progressive-ratio schedules",
Society of Neuroscience,
New Orleans,
Louisiana,
United States.
October 01, 1997.
Voeller, R. K., Gale, C. A., J. B.
"INT1 expression in Saccharomyces cerevisiae",
Life Sciences Summer Undergraduate Research Program Poster Symposium,
University of Minnesota,
Twin Cities,
Minnesota,
United States.
August 01, 1997.
Contact
Contact
Address
Division of Cardiothoracic Surgery420 Delaware St. S.E., MMC 207
Minneapolis, MN 55455
Administrative Contact
Tina Russell | 612-625-1096 | russe041@umn.edu
Tessa Watt
, MD, MSc
Assistant Professor, Division of Cardiothoracic Surgery
tmfwatt@umn.edu
(612) 625-3902
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Assistant Professor, Division of Cardiothoracic Surgery
Biography
Bio
Dr. Watt obtained her undergraduate degree from Stanford University and medical degree from the University of Michigan. She remained at University of Michigan for Cardiothoracic Surgery Residency training as well as Advanced Heart Failure and Mitral Surgery Fellowship. During her training she also obtained a Master of Health and Healthcare Research degree from the Institute for Health Policy and Innovation and completed a fellowship in Surgical Critical Care at University of Michigan.
Dr. Watt is committed to providing evidence-based, patient-focused care in the surgical treatment of advanced heart conditions. The primary tenant of her care philosophy is always putting patients first.
Research Summary
Dr. Watt’s research interests include cardiothoracic surgical outcomes, mitral valve repair, heart failure and mechanical circulatory support, cardiac transplant recipient outcomes, organ donor optimization, surgical education, and the use of video analysis to evaluate and improve surgical skill and technique.
Clinical Summary
Coronary Revascularization (coronary artery bypass grafting); Valvular Heart Disease including Mitral Valve Repair; Aortic Surgery and Reconstruction; Heart Failure and Ventricular Assist Devices (VADs); Mechanical Circulatory Support; Heart Transplantation
Education
MD,
University of Michigan
MSc,
University of Michigan
BA,
Stanford University
Fellowships, Residencies, and Visiting Engagements
Surgical Critical Care Fellowship,
University of Michigan
Advanced Heart Failure and Mitral Surgery Fellowship,
University of Michigan
Cardiothoracic Surgery Residency,
University of Michigan
Honors and Recognition
Women in Thoracic Surgery (WTS) Scholarship
University of Michigan Medical School Dean's Awards for Graduation with Distinction in Research, Service, and Medical Education
Southern Thoracic Surgical Association (STSA) Hawley Seiler Residents Award
Professional Memberships
American College of Surgeons
Society of Thoracic Surgeons
American Medical Association
Society of Critical Care Medicine
Women in Thoracic Surgery
STS Political Action Committee (STS-PAC)
Contact
Eric Wise
, MD, MA
Assistant Professor, Division of Gastrointestinal/Bariatric Surgery
wise0147@umn.edu
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Assistant Professor, Division of Gastrointestinal/Bariatric Surgery
Email:
wise0147@umn.edu
Affiliation:
Department of Surgery
Biography
Bio
I enjoy practicing medicine at the University of Minnesota, where we have every resource in place to ensure the best possible outcome for each patient. As a general and bariatric surgeon, I believe in taking a very thoughtful approach with each patient, sometimes leading to surgery but many times not. I am very involved in clinical and basic science research as well, as only through this process of discovery can we develop better treatments for the surgical disease we see on a daily basis.
Research Summary
Medical device development, physiology, clinical applications of artificial intelligence.
Clinical Summary
Bariatric Surgery; Benign diseases of the foregut; Hernia; Gallbladder; General Surgery
Contact
Contact
Address
Department of Surgery319 Variety Club Research Center
401 E River Parkway, Minneapolis, MN, 55455
Administrative Contact
Inna Potapenko | potap014@umn.edu
K. Joshua Wong
, MD
Assistant Professor, Division of Cardiothoracic Surgery
wong0649@umn.edu
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Assistant Professor, Division of Cardiothoracic Surgery
Email:
wong0649@umn.edu
Biography
Bio
He received his Medical Degree from the Jefferson Medical College - Thomas Jefferson University, completed his General Surgery residency at the University of Rochester and recently completed a Cardiothoracic Fellowship with the University of Minnesota Medical School.
Dr. Wong is an expert in adult cardiac surgery, coronary artery revascularization, mechanical circulatory support, and heart and lung transplantation. He is driven to provide excellence in care to patients and teach and mentor the next generation of cardiothoracic surgeons.
Dr. Wong's research interests are focused on surgical outcomes after adult cardiac surgery, surgical education, and Mechanical Circulatory Support (ECMO/LVAD)-Medical device innovation.
"I am excited to be joining and working with the outstanding group of individuals who comprise the Department of Surgery," said Dr. Wong. "It will be my goal to help grow the clinical, educational, and research endeavors of our Division. I thank my U of M mentors for my growth as a surgeon."
Research Summary
Surgical outcomes after adult cardiac surgery; Mechanical Circulatory Support (ECMO/LVAD)-Medical device innovation; Surgical Education
Clinical Summary
Coronary (multi-arterial) revascularization; complex aortic surgery; structural heart disease; mechanical circulatory support; heart and lung transplantation
Contact
Contact
Address
Division of Cardiothoracic Surgery420 Delaware St. S.E., MMC 207
Minneapolis, MN, 55455
Administrative Contact
Tina Russell | 612-625-1096 | russe041@umn.edu
Masato Yamamoto
, MD, PhD
Professor and Chief of Basic and Translational Research
yamam016@umn.edu
(612) 624-9131
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Professor and Chief of Basic and Translational Research
Biography
Research Summary
Cancer gene therapy with Adenovirus Vector Conditionally replicative adenovirus for the treatment of cancer Non-invasive in vivo molecular imaging Gene therapy of gastrointestinal diseases, pancreatic cancer, esophageal cancer, prostate cancer, breast cancer, and multiple myeloma Cancer gene-therapy and virotherapy Our goal is to develop clinically usable gene-/viro-therapy modalities for solid tumors, e.g. GI cancers including pancreatic cancer. Our group has been developing cancer therapeutics with adenovirus as gene delivery tool. Current gene therapy modalities for cancer have not achieved the expected therapeutic efficiency due to disease related obstacles. Our lab is developing advanced version of adenovirus vectors and oncolytic adenoviruses by employing virological advance. We perform extensive vector engineering and produce the viruses/vectors to overcome the issues impeding clinical realization of this kind of therapeutics. Recent advances include 1) Development of adenovirus targeting ligand library and its application to the targeted delivery upon systemic administration, 2) Theranostics enables tumor imaging and tumor selective radiotherapy employing sodium-iodine symporter, 3) Combination viro-therapy with INF-alpha expressing oncolytic adenovirus and chemoradiation, 4) Development of cancer stem cell targeted oncolytic adenovirus.
Contact
Contact
Address
11-216 MMT Bldg515 Delaware St SE
Minneapolis, MN 55455
Administrative Contact
Kelli Tourand | 612-624-4581 | toura018@umn.edu
Rui Zhang
, PhD
Associate Professor and Chief, Division of Computational Health Sciences
zhan1386@umn.edu
View full bio
This is a dialog window which overlays the main content of the page. Pressing the Close Modal "X" button at the top of the modal will close the modal and bring you back to where you were on the page.
Associate Professor and Chief, Division of Computational Health Sciences
Biography
Bio
Rui Zhang, PhD, FAMIA, Chief of the Division of Computational Health Sciences in the News:
- Research Spotlight: Dr. Zhang Received an R01 Renewal Developing Novel AI Approach to Mine Effective & Safe Use of Dietary Supplements
- Dr. Zhang Received a New R01 to Research Drug Repurposing for Alzheimer's Disease
- U of M researchers receive $1.2M to study role of AI in breast cancer treatment
- Center for Learning Health System Sciences: All of Us Risk Modeling
- Detecting synergistic effects of pharmacological and non-pharmacological interventions for Alzheimer's disease and related dementia
Education
PhD,
University of Minnesota
Major: Health Informatics
MS,
University of Iowa
Major: Informatics
MS,
University of Iowa
Major: Chemistry
MS,
University of Science & Technology of China
Major: Chemistry
Honors and Recognition
Outstanding Teaching and Dedication, Center for Educational Innovation, UMN
2019
Student paper competition finalist, Post-doctorate associate’s manuscript (senior author) , AMIA Translational Bioinformatics
2018
Undergraduate Research Opportunity Program (UROP) Award, Advisor for undergraduate students, University of Minnesota
2018
Doctoral Dissertation Fellowship, PhD student awarded the (as her primary advisor), University of Minnesota
2018
Student paper competition, PhD student’s manuscript (senior author), AMIA Translational Bioinformatics
2017
McKnight Land-Grant Professorship Award , University of Minnesota
2017
Research project highlighted, How Your Supplements Interact With Prescription Drugs, The Wall Street Journal Health Headline
2016
Best Poster Award, IEEE International Conference on Biomedical and Health Informatics
2016
Distinguished Paper Award , AMIA Annual Symposium
2016
Marco Ramoni Distinguished Paper Award , Manuscript (first author) , Translational Bioinformatics
2015
University of Minnesota Informatics Institute (UMII) On the Horizon Award , University of Minnesota
2014
Student paper competition finalist, Manuscript (first author) , AMIA Joint Summits on Translational Science
2014
Editors’ Choice, Journal of Biomedical Informatics
2014
Scholarship, Health Information and Management Systems Society (HIMSS) Minnesota Chapter
2013
Student paper competition finalist, Manuscript (first author) , MEDINFO - The14th World Congress on Medical and Health Informatics of the International Medical Informatics Association
2013
Travel Award, Association for Computing Machinery
2012
Travel Award, University of Minnesota
2012
Health Informatics Graduate Fellowship, University of Minnesota
2012
Doctoral Dissertation Fellowship (All-University Competition), University of Minnesota
2012
Fellowship of the International Partnership in Health Informatics Education (IPHIE) Master Class, , University of Heidelberg-University of Heilbronn, Germany
2011
Student paper competition finalist, Manuscript (first author) , AMIA Annual Symposium
2011
Travel Award, American Medical Informatics Association
2011
Media Appearances
How Your Supplements Interact With Prescription Drugs, The Wall Street Journal
2016
Professional Memberships
AMIA Education Committee
2014-2015
AMIA Student Working Group
2013-2015
AMIA Membership/Outreach Committee
2014-2014
American Medical Informatics Association
Selected Publications
Selected Publications
Bompelli, A., Silverman, G., Finzel, R., Vasilakes, J., Knoll, B., Pakhomov, S., Zhang, R.,
2020.
Comparing NLP Systems to Extract Entities of Eligibility Criteria in Dietary Supplements Clinical Trials Using NLP-ADAPT.
International Conference on Artificial Intelligence in Medicine
67--77.
Yi, Y., Shen, Z., Bompelli, A., Yu, F., Wang, Y., Zhang, R.,
2020.
Natural Language Processing Methods to Extract Lifestyle Exposures for Alzheimer’s Disease from Clinical Notes.
(IEEE ICHI).
HealthNLP Workshop
2020
He, Z., Barrett, L. A., Rizvi, R., Tang, X., Payrovnaziri, S. N., Zhang, R.,
2020.
Assessing the Use and Perception of Dietary Supplements Among Obese Patients with National Health and Nutrition Examination Survey.
AMIA Summits on Translational Science Proceedings,
2020
231.
Vasilakes, J., Rizvi, R., Terrence, A., R, Z.,
2019.
Detecting Signals of Dietary Supplement Adverse Events from the CFSAN Adverse Event Reporting System (CAERS).
AMIA Informatics Summit
He, Z., Rizvi, R., Terrence, A., Zhang, R.,
2019.
Comparing the Study Populations in Dietary Supplement and Drug Clinical Trials for Metabolic Syndrome and Related Disorders. (in press).
AMIA Informatics Summit,
Ma, S., Zhang, R., Shanahan, L., Munroe, J., Horn, S., Speedie, S.,
2018.
Estimating New York Heart Association Classification for Heart Failure Patients from Information in the Electronic Health Record..
IEEE International conference on Bioinformatics and Biomedicine
He, X., Zhang, R., Rizvi, R., Vasilakes, J., Yang, X., Guo, Y., He, Z., Bian, J.,
2018.
Prototyping an Interactive Visualization of Dietary Supplement Knowledge Graph.
IEEE International Conference on Bioinformatics and Biomedicine
Rizvi, R. F., Adam, T. J., Lindemann, E. A., Vasilakes, J., Pakhomov, S. V., Bishop, J. R., Melton, G. B., Zhang, R.,
2018.
Comparing Existing Resources to Represent Dietary Supplements.
AMIA Summits on Translational Science Proceedings,
2017
207-216.
Fan, Y., Zhang, R.,
2018.
Using natural language processing methods to classify use status of dietary supplements in clinical notes.
BMC medical informatics and decision making,
18
(Suppl 2):
51.
Zhang, R., Meng, J., Lian, Q., Chen, X., Bauman, B., Chu, H., Segura, B., Roy, S.,
2018.
Prescription opioids are associated with higher mortality in patients diagnosed with sepsis: A retrospective cohort study using electronic health records.
PLoS ONE,
13
(1):
e0190362.
Vasilakes, J., Rizvi, R., Melton, G. B., Pakhomov, S., Zhang, R.,
2018.
Evaluating active learning methods for annotating semantic predications.
JAMIA Open,
1
(2):
275--282.
Breitenstein, M. K., Liu, H., Maxwell, K. N., Pathak, J., Zhang, R.,
2018.
Electronic Health Record Phenotypes for Precision Medicine: Perspectives and Caveats from Treatment of Breast Cancer at a Single Institution.
Clinical and Translational Science,
11
(1):
85-92.
Pope, Z., Zeng, N., Zhang, R., Lee, H., Gao, Z.,
2018.
Effectiveness of Combined Smartwatch and Social Media Intervention on Breast Cancer Survivor Health Outcomes: A 10-Week Pilot Randomized Trial.
Journal of clinical medicine,
7
(6):
140.
Zhang, R., Ma, S., Shanahan, L., Munroe, J., Horn, S., Speedie, S.,
2018.
Discovering and identifying New York heart association classification from electronic health records.
BMC medical informatics and decision making,
18
(2):
48.
He, Z., Tao, C., Bian, J., Zhang, R., Huang, J.,
2018.
Introduction: selected extended articles from the 2nd International Workshop on Semantics-Powered Data Analytics (SEPDA 2017).
BioMed Central,
Wang, Y., Zhao, Y., Bian, J., Zhang, R.,
2018.
Detecting Signals of Associations Between Dietary Supplement Use and Mental Disorders from Twitter.
2018 IEEE International Conference on Healthcare Informatics Workshop (ICHI-W)
53--54.
Hultman, G., McEwan, R., Knoll, B., Zhang, R., Pakhomov, S.,
NLP-PIER 2.0: A Redesigned Clinical Document Search Interface for Researchers..
(AMIA Clinical Informatics).
Selected Presentations
Selected Presentations
Zhang, R.
"(Invited) Biomedical natural language processing for information extraction and knowledge discovery",
Indiana University/Regenstrief Institute,
Indiana University/Regenstrief Institute,
Indianapolis,
Indiana,
January 22, 2019.
Ma, S., (Author & Presenter), Zhang, R., (Author)
"Estimating New York Heart Association Classification for Heart Failure Patients from Information in the Electronic Health Record",
IEEE International conference on Bioinformatics and Biomedicine.,
December 03, 2018.
He, X., Zhang, R.
"Prototyping an Interactive Visualization of Dietary Supplement Knowledge Graph",
IEEE International Conference on Bioinformatics and Biomedicine,
December 03, 2018.
Zhang, R.
"Data science in healthcare: natural language processing to unlock healthcare information",
Wayne State University,
Detriot,
Michigan,
November 18, 2018.
Zhang, R.
"Biomedical text analytics for computational health sciences",
Weill Cornell Medical College, Cornell University,
Weill Cornell Medical College, Cornell University,
New York,
New York,
October 22, 2018.
Zhang, R.
"Analyzing clinical texts for computational health sciences",
Anthem Inc, ,
Chicago,
October 11, 2018.
Zhang, R.
"Mining adverse events of supplements using product labeling data",
NIH, Office of Dietary Supplements,
September 18, 2018.
Zhang, R.
"Data Science for Discovering and Monitoring Drug Safety on Biomedical Big Data",
COP presentation for Shenyang Pharmaceutical University,
University of Minnesota,
August 17, 2018.
Zhang, R.
"Unlocking clinical records for computational health sciences",
University of California San Francisco,
San Francisco,
California,
July 25, 2018.
Wang, Y., (Author & Presenter), Zhang, R., (Author)
"Detecting Signals of Associations Between Dietary Supplement Use and Mental Disorders from Twitter.",
2018 IEEE International Conference on Healthcare Informatics Workshop (ICHI-W) ,
June 07, 2018.
Rizvi, R., (Author & Presenter), Zhang, R., (Author)
"Comparing Existing Resources to Represent Dietary Supplements ",
American Medical Informatics Association Annual Symposium,
AMIA,
San Francisco,
California,
United States.
March 01, 2018.
Fan, Y., (Author & Presenter)
"Evaluating Automatic Methods to Extract Patients’ Supplement Use from Clinical Reports",
IEEE International conference on Bioinformatics and Biomedicine,
Kansas city,
Kansas,
November 13, 2017.
Zhang, R., (Author & Presenter)
"Automatic Methods to Extract New York Heart Association Classification from Clinical Notes",
IEEE International conference on Bioinformatics and Biomedicine,
Kansas city,
Kansas,
United States.
November 13, 2017.
Sun, D.
"Causal Phenotyping for Susceptibility to Cardiotoxicity from Antineoplastic Breast Cancer Medications",
Proceedings of the American Medical Informatics Association Symposium,
Philips,
Washington DC,
November 08, 2017.
Zhang, R.
"Data Science for Discovering and Monitoring Adverse Drug Events",
Department of Surgery Resident Research Enrichment Program,
University of Minnesota,
Minneapolis,
Minnesota,
October 26, 2017.
Zhang, R.
"Health Informatics to support Precision Medicine",
The Minnesota Precision Medicine Collaborative Seminar. University of Minnesota, ,
Minneapolis,
Minnesota,
October 06, 2017.
Zhang, R.
"Natural language processing to support dietary supplement research",
American Medical Informatics Association NLP working group webinar,
University of Minnesota,
October 03, 2017.
Fan, Y.
"Detecting Signals of Interactions between Warfarin and Supplements in Electronic Health Records",
The 16th World Congress on Medical and Health Informatics,
Hangzhou,
China.
August 01, 2017.
Wang, Y., (Author & Presenter)
"Mining Adverse Events of Dietary Supplements from Product Labels by Topic Modeling",
The 16th World Congress on Medical and Health Informatics,,
Hangzhou,
China.
August 01, 2017.
Sun, D., (Author & Presenter)
"Phenotyping and Visualizing Infustion-related Reactions for Breast Cancer Patients.",
The 16th World Congress on Medical and Health Informatics,
Philips,
Hangzhou,
China.
August 01, 2017.
Zhang, R.
"Health Informatics to facilitate clinical and translational research",
College of Pharmacy Clinical Retreat, University of Minnesota,
University of Minnesota,
Minneapolis,
Minnesota,
June 08, 2017.
Zhang, R.
"Unlocking patient information and pharmacovigilance knowledge from clinical narratives and biomedical literature",
Department of Medicine, University of Minnesota,
Minneapolis,
Minnesota,
March 06, 2017.
Zhang, R.
"Natural language processing in healthcare domain",
Biomedical informatics, Department of health outcomes and policy, College of Medicine, University of Florida,
University of Minnesota,
February 22, 2017.
Zhang, R.
"Big data science for drug safety",
College of Pharmacy, University of Minnesota,
Minneapolis,
Minnesota,
February 07, 2017.
Zhang, R., (Author & Presenter)
"Detecting Clinically Relevant New Information in Clinical Notes Across Specialties and Settings",
ICIBM,
Houston,
Texas,
December 08, 2016.
Fan, Y., (Author & Presenter)
"Classification of Status for Supplement Use in Clinical Notes.",
Proceedings of the IEEE International conference on Bioinformatics and Biomedicine,
Shenzhen,
China.
December 01, 2016.
Marc, D.
"Assessing Metadata Quality of a Federally Sponsored Health Data Repository",
AMIA Annual Symposium,
AMIA Annual Symposium,
Chicago,
Illinois,
November 01, 2016.
Wang, Y., (Author & Presenter)
"Term Coverage of Herb and Dietary Supplements in Product Labels",
AMIA Annual Symposium,
Chicago,
Illinois,
November 01, 2016.
Zhang, R.
"Applying Active Learning to Semantic Predications in SemMedDB",
Department of Surgery Graduation Day Poster Session. University of Minnesota,
University of Minnesota,
Minneapolis,
Minnesota,
June 14, 2016.
Zhang, R.
"Health Informatics: when informatics and health big data meet",
Computer Engineering and Systems, Texas A&M University,
University of Minnesota,
Texas,
April 14, 2016.
Zhang, R.
"Big Data to Knowledge (BD2K): mining literature to discover drug-supplement interactions",
Surgical Ground Rounds,University of Minnesota,
Minneapolis,
Minnesota,
March 01, 2016.
Chen, X.
"Applying Active Learning to Semantic Predications in SemMedDB",
IEEE International Conference on Biomedical and Health Informatics,
Las Vegas,
Nevada,
February 01, 2016.
Zhang, R.
"Applying Active Learning to Semantic Predications in SemMedDB",
IEEE International Conference on Biomedical and Health Informatics.,
Las vegas,
Nevada,
February 01, 2016.
Zhang, R., (Author & Presenter)
"Evaluating Term Coverage of Herbal and Dietary Supplements in Electronic Health Records.",
Proceedings of the American Medical Informatics Association Symposium,
San Francisco,
California,
November 01, 2015.
Manohar, N.
"Evaluation of herbal and nutritional supplement resource term coverage",
MEDINFO '15,
West Side Community Health Services,
São Paulo,
Brazil.
August 01, 2015.
Marc, D.
"Indexing Publicly Available Health Data with Medical Subject Headings (MeSH): An Evaluation of Term Coverage",
MEDINFO '15,
São Paulo,
Brazil.
August 01, 2015.
Zhang, R.
"Mining Biomedical Literature to Explore Interactions between Cancer Drugs and Dietary Supplements",
American Medical Informatics Association Translational Bioinformatics Summit,
University of Minnesota,
San Francisco,
California,
March 24, 2015.
Zhang, R., (Author & Presenter)
"Using Language Models to Identify Relevant New Information in Inpatient Clinical Notes",
American Medical Informatics Association Annual Symposium ,
Washington DC,
November 01, 2014.
Zhang, R.
"Mining textual information in clinical notes and biomedical literature",
Academic Health Center informatics grand round, University of Minnesota,
Minneapolis,
Minnesota,
October 09, 2014.
Zhang, R.
"Getting the Most out of the AMIA 2014 Annual Symposium: Participating in AMIA as a Student Attendee",
American Medical Informatics Association Symposium webinar,
University of Minnesota,
October 02, 2014.
Zhang, R.
"Leveraging natural language processing in health sciences",
Department of Surgery Monthly Research Seminar,University of Minnesota,
Minneapolis,
Minnesota,
September 18, 2014.
Zhang, R.
"Preparing for scholarly presentations for AMIA Annual Symposium",
American Medical Informatics Association Symposium webinar,
University of Minnesota,
August 26, 2014.
Zhang, R.
"Introduction to Clinical Informatics",
Department of Social and Public Health, Ohio University,
University of Minnesota,
Athen,
Ohio,
April 12, 2013.
Zhang, R.
"Automatic methods to identify new information of patients from clinical texts",
Doctoral Research Showcase, University of Minnesota,
Minneapolis,
Minnesota,
April 09, 2013.
Zhang, R.
"Natural Language Processing in Health Sciences",
University of Minnesota,
Briarcliff Mano,
New York,
April 08, 2013.
Zhang, R.
"Natural Language Processing in Health Sciences",
School of Information Studies, University of Wisconsin,
University of Minnesota,
Milwaukee,
Wisconsin,
March 08, 2013.
Zhang, R., (Author & Presenter)
"Automated Assessment of Medical Training Evaluation Text.",
American Medical Informatics Association Symposium,
University of Minnesota,
Chicago,
Illinois,
November 01, 2012.
Zhang, R.
"Discovery of potential drug interactions from biomedical literatures",
Seminar, Department of Experimental and Clinical Pharmacy, University of Minnesota,
Minneaplois,
Minnesota,
September 01, 2012.
Zhang, R.
"Evaluating measures of redundancy in clinical texts",
Seminar, Institute for Health Informatics, University of Minnesota,,
Minneapolis,
Minnesota,
September 01, 2012.
Zhang, R.
"Using semantic predications to uncover drug-drug interactions in clinical notes",
Seminar, National Library of Medicine, National Institutes of Health,,
University of Minnesota,
Bethesda,
Maryland,
August 22, 2012.
Zhang, R.
"Automated identification of new useful information in clinical narrative",
2nd ACM SIGHIT (SIG on Health Informatics) International Health Informatics Symposium ,
Miami Beach,
Florida,
January 01, 2012.
Zhang, R., (Author & Presenter)
" Evaluating measures of redundancy in clinical text",
American Medical Informatics Association Symposium,
University of Minnesota,
Washington DC,
October 01, 2011.
Grants and Patents
Grants and Patents
Selected Grants
Other Grants
Award: Racial disparities in access to kidney transplantation
Principal Investigator: Rui Zhang, PhD, FAMIA
Role: Multiple Principal Investigator
Sponsoring Organization: NIH/NIDDK R01DK115629
Award Dates: 2024 - 2029
Award: Mining minority enriched AllofUs data for innovative ethnic specific risk prediction modeling
Principal Investigator: Rui Zhang, PhD, FAMIA
Role: Principal Investigator
Sponsoring Organization: NIH/NIHMD 1R21MD019134-01 (PI: Zhang/Wang/Hou)
Award Dates: 2023 - 2025
Award: SCH: A New Computational Framework for Learning from Imbalanced Biomedical Data
Principal Investigator: Rui Zhang, PhD, FAMIA
Role: Multiple Principal Investigator
Sponsoring Organization: NIH/NCI 1R01CA287413-01 (PI: Sun/Cui/Zhang)
Award Dates: 2023 - 2027
Award: A Translational Informatics Framework to Mine Efficacy and Safety of Dietary Supplements
Principal Investigator: Rui Zhang, PhD, FAMIA
Role: Principal Investigator
Sponsoring Organization: NIH/NCCIH 2R01AT009457-05A1 (PI: Zhang)
Award Dates: 2023 - 2027
Funded Amount: 3100000
Award: Detecting synergistic effects of pharmacological and non-pharmacological interventions for AD/ADRD
Principal Investigator: Rui Zhang, PhD, FAMIA
Role: Principal Investigator
Sponsoring Organization: NIH/National Institution on Aging 1R01AG078154-01 (PI: Zhang/Xu)
Award Dates: 2022 - 2027
Funded Amount: 3900000
Contact
Contact
Address
7-115A Weaver-Densford Hall308 Harvard Street SE
Minneaplis, MN 55455