Andrew Adams

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Credentials

MD, PhD

Bio

As a transplant surgeon and scientist, Dr. Adams is interested in developing the best therapies and diagnostics for transplant patients, by understanding the fundamental mechanisms of the immune system that give rise to organ rejection. As a graduate student, under the direction of Drs. Chris Larsen and Tom Pearson, Dr. Adams investigated the efficacy of costimulation blockade and helped develop Belatacept, now a clinically available therapy for transplant patients. Belatacept leads to improved survival and kidney function for renal transplant patients. The Adams' Lab has four main areas of investigation (1) costimulation blockade and costimulation independent rejection (2) xenotransplantation (3) transplant diagnostics (4) transplant outcomes.

Research Summary

Dr. Adams research efforts are concentrated on the development of novel strategies and therapeutics to promote transplantation tolerance. He has made important contributions to our understanding concerning the interplay between viral infection, immune memory and the allo-immune response. Dr. Adams is also an internationally recognized expert in large animal models of xenotransplantation (pig-to-non-human primateorgan transplant).

Clinical Summary

Kidney Transplant, Liver Transplant, Pediatric Transplant, Xenotransplant