Amit Bhargava, MD, MHA, FACS
Deidra Nutt | 612-625-0998 | [email protected]
MMC 195
420 Delaware Street SE
Minneapolis, MN, 55455
Education
MD, University of Wisconsin Medical School
Publications
Publications
Asterisk(*) - indicates co-first author
Underline - indicates student author
Peer-Reviewed Publications
1. Salami, A. C., Diaz-Gutierrez, I., Bhargava, A., Andrade, R., Rao, M. V. (2025). Multidisciplinary management of a complex case of postesophagectomy tracheoesophageal fistula. JTCVS Techniques, 30, 159-161. doi: 10.1016/j.xjtc.2024.12.005
2. Vaidya, Y., Polycarpou, A., Gibbs, S., Rao, M., Bhargava, A., Andrade, R., Diaz-Gutierrez, I. (2025). Surgical approaches for thymectomy: a narrative review. Mediastinum, 9, 5-5. doi: 10.21037/med-24-38
3. Mendez, R., Racila, E., Andrade, R., Bhargava, A. (2024). Extrapleural Pneumonectomy for Treatment of Pulmonary Adenoid Cystic Carcinoma. Annals of Thoracic Surgery Short Reports. doi: 10.1016/j.atssr.2024.10.022
4. Salami, A. C., Rao, M., Berger, J., Diaz-Gutierrez, I., Khariwala, S. S., Khaja, S. F., Sembrano, J. N., Hunt, M., Andrade, R., Bhargava, A. (2024). Esophageal perforation after anterior cervical spine surgery. JTCVS Techniques, 25, 208-213. doi: 10.1016/j.xjtc.2024.03.014
5. Salami, A. C., Mendez, R., Bhargava, A. (2024). Narrative Review on minimally invasive metastasectomy for head and neck malignancies. VATS, Volume 9. doi: 10.21037/vats-23-66
6. Schoephoerster, J., Praska1, C., White, M., Salami, A., Marmor, S., Andrade, R., Bhargava, A., Diaz-Gutierrez, I., Hui, J., Tuttle, T., Owen, M., Rao, M. (in press, accepted September 2023). A nationwide analysis of disparities in guideline-concordant care in American Indians and Alaska Natives with stage I non-small cell lung cancer. Journal of Thoracic Disease. doi: 10.21037/jtd-23-801
7. Rao, M., Salami, A., Robbins, A., Schoephoerster, J., Bhargava, A., Diaz-Gutierrez, I., Wang, Q., Andrade, R. (2022). Subxiphoid-subcostal versus transthoracic thoracoscopic thymectomy: A safe and feasible approach. JTCVS Techniques, 16, 172-181. PMID: 365108515 PMCID: PMC9735327 doi: 10.1016/j.xjtc.2022.08.017
8. Diaz-Gutierrez, I., Doyle, J. E., Majumder, K., Wang, Q., Rao, M. V., Bhargava, A., Andrade, R. S. (2022). Nonsupercharged Retrosternal Roux-en-Y Esophagojejunostomy for Distal Esophageal Reconstruction. The Annals of Thoracic Surgery, 114(4), 1152-1158. PMCID: 34624265 doi: 10.1016/j.athoracsur.2021.08.069
9. Jones, E. K., Andrade, R., Bhargava, A., Diaz-Gutierrez, I., Rao, M. (2022). Surgical management of delayed-presentation diaphragm hernia: A single-institution experience. JTCVS Techniques, 13, 263-269. PMID: 35711179 PMCID: PMC9197083 doi: 10.1016/j.xjtc.2022.04.012
10. Van Ochten, N., Rao, M. V., Bhargava, A., Andrade, R. S., Diaz-Gutierrez, I. (2022). Right pneumonectomy for invasive pulmonary mucormycosis. JTCVS Techniques, 11, 81-85. doi: 10.1016/j.xjtc.2021.09.057
11. Diaz-Gutierrez, I., Robbins, A. J., Zhang, B., Rao, M. V., Bhargava, A., Andrade, R. S. (2021). Long-Term Results of Diaphragmatic Hernia Repair After Left Ventricular Assist Device Explantation. The Annals of Thoracic Surgery, 112(3), 874-879. PMID: 33186603 doi: 10.1016/j.athoracsur.2020.10.016
12. Bhargava, A., Andrade, R. (2020). Laparoscopic Repair of Giant Hiatal Hernia: A Narrative Review. Shanghai Chest(2521-3768).
13. Bhargava, A., Andrade, R. (2020). Giant paraesophageal hernia: What do we really know? JTCVS Techniques, 3, 367-372. doi: 10.1016/j.xjtc.2020.08.021
14. Marmor, S., Fujioka, N., Cho, L., Bhargava, A., Misono, S. Dysphagia Prevalence and Associated Survival Differences in Older Patients with Lung Cancer: A SEER-Medicare Population-Based Study. Journal of Geriatric Oncology, March 2020. PMID: 32169546 doi: 10.1016/j.jgo.2020.02.015
15. Jain, S., Dayma, V., Sharma, P., Bhargava, A., Baroliya, P. K., Goswami, A. K. (2020). Synthesis of Some New Hydroxytriazenes and their Antimicrobial and Anti-inflammatory Activities. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry, 19(1), 50-60. doi: 10.2174/1871523018666190301151826
16. Andrade, R. S., Bhargava, A. (2018). No pain, No gain. European Journal of Cardio-Thoracic Surgery, 54(6), 969-970. doi: 10.1093/ejcts/ezy347
17. Su, C. T., Bhargava, A., Shah, C. D., Halmos, B., Gucalp, R. A., Packer, S. H., Ohri, N., Haramati, L. B., Perez-Soler, R., Cheng, H. (2018). Screening Patterns and Mortality Differences in Patients With Lung Cancer at an Urban Underserved Community. Clinical Lung Cancer, 19(5), e767-e773. doi: 10.1016/j.cllc.2018.05.019
18. Bhargava, A., Abbas, G., Landreneau, R. J. (2012). Radiofrequency Ablation of Lung Cancer. Cardiothoracic Surgery Review.
19. Bhargava, A., Shuchert, M. J., Landreneau, R. J. (2012). Role of Esophageal Stents in the Management of Malignant and Benign Esophageal Strictures. Cardiothoracic Surgery Review.
20. Fong, Y., Kim, T., Bhargava, A., Schwartz, L., Brown, K., Brody, L., Covey, A., Karrasch, M., Getrajdman, G., Mescheder, A., Jarnagin, W., Kemeny, N. (2009). A Herpes Oncolytic Virus Can Be Delivered Via the Vasculature to Produce Biologic Changes in Human Colorectal Cancer. Molecular Therapy, 17(2), 389-394. doi: 10.1038/mt.2008.240
published in Epub on November 18, 2008
21. Riedl, C. C., Akhurst, T., Larson, S., Stanziale, S. F., Tuorto, S., Bhargava, A., Hricak, H., Klimstra, D., Fong, Y. (2007). 18F-FDG PET scanning correlates with tissue markers of poor prognosis and predicts mortality for patients after liver resection for colorectal metastases. Journal of Nuclear Medicine, 48(5), 771-775.
22. Derubertis, B. G., Stiles, B. M., Bhargava, A., Gusani, N. J., Hezel, M., D'Angelica, M., Fong, Y. (2007). Cytokine-secreting herpes viral mutants effectively treat tumor in a murine metastatic colorectal liver model by oncolytic and T-cell-dependent mechanisms. Cancer Gene Therapy, 14(6), 590-597.
Published in Epub April 13, 2007
23. Stiles, B., Adusumilli, P., Stanziale, S., Eisenberg, D., Bhargava, A., Kim, T., Chan, M.-K., Huq, R., Gonen, M., Fong, Y. (2006). Estrogen enhances the efficacy of an oncolytic HSV-1 mutant in the treatment of estrogen receptor-positive breast cancer. International Journal of Oncology, 28(6), 1429-1439. doi: 10.3892/ijo.28.6.1429
24. Stiles, B. M., Adusumilli, P. S., Bhargava, A., Fong, Y. (2006). Fluorescent cholangiography in a mouse model: an innovative method for improved laparoscopic identification of the biliary anatomy. Surgical Endoscopy, 20(8), 1291-1295.
Published in Epub July 20, 2006
25. Stiles, B. M., Adusumilli, P. S., Bhargava, A., Stanziale, S. F., Kim, T. H., Chan, M. K., Huq, R., Wong, R., Rusch, V. W., Fong, Y. (2006). Minimally invasive localization of oncolytic herpes simplex viral therapy of metastatic pleural cancer. Cancer Gene Therapy, 13(1), 53-64.
26. Kemeny, N., Brown, K., Covey, A., Kim, T., Bhargava, A., Brody, L., Guilfoyle, B., Haag, N. P., Karrasch, M., Glasschroeder, B., Knoll, A., Getrajdman, G., Kowal, K. J., Jarnagin, W. R., Fong, Y. (2006). Phase I, Open-Label, Dose-Escalating Study of a Genetically Engineered Herpes Simplex Virus, NV1020, in Subjects with Metastatic Colorectal Carcinoma to the Liver. Human Gene Therapy, 17(12), 1214-1224. doi: 10.1089/hum.2006.17.1214
27. Mullerad, M., Eisenberg, D. P., Akhurst, T. J., Adusumilli, P. S., Riedl, C. C., Bhargava, A., Gonen, M., Finn, R., Scardino, P. T., Fong, Y. (2006). Use of positron emission tomography to target prostate cancer gene therapy by oncolytic herpes simplex virus. Molecular Imaging and Biology, 8(1), 30-35.
28. Mullerad, M., Bochner, B. H., Adusumilli, P. S., Bhargava, A., Kikuchi, E., Hui-Ni, C., Kattan, M. W., Chou, T. C., Fong, Y. (2005). Herpes simplex virus based therapy enhances the efficacy of mitomycin C for the treatment of human bladder transitional cell carcinoma. Journal of Urology, 174(2), 741-746.
29. MULLERAD, M., BOCHNER, B. H., ADUSUMILLI, P. S., BHARGAVA, A., KIKUCHI, E., HUI-NI, C., KATTAN, M. W., CHOU, T.-C., FONG, Y. (2005). HERPES SIMPLEX VIRUS BASED GENE THERAPY ENHANCES THE EFFICACY OF MITOMYCIN C FOR THE TREATMENT OF HUMAN BLADDER TRANSITIONAL CELL CARCINOMA. Journal of Urology, 174(2), 741-746. doi: 10.1097/01.ju.0000164730.38431.5c
30. Delman, K. A., Zager, J. S., Bhargava, A., Petrowsky, H., Malhotra, S., Ebright, M. I., Bennett, J. J., Gusani, N. J., Kooby, D. A., Roberts, G. D., Fong, Y. (2004). Effect of murine liver cell proliferation on herpes viral behavior: Implications for oncolytic viral therapy. Hepatology, 39(6), 1525-1532. doi: 10.1002/hep.20198
31. Stanziale, S. F., Stiles, B. M., Bhargava, A., Kerns, S. A., Kalakonda, N., Fong, Y. (2004). Oncolytic Herpes Simplex Virus-1 Mutant Expressing Green Fluorescent Protein Can Detect and Treat Peritoneal Cancer. Human Gene Therapy, 15(6), 609-618. doi: 10.1089/104303404323142051
32. Wong, R. J., Chan, M.-K., Yu, Z., Kim, T. H., Bhargava, A., Stiles, B. M., Horsburgh, B. C., Shah, J. P., Ghossein, R. A., Singh, B., Fong, Y. (2004). Effective Intravenous Therapy of Murine Pulmonary Metastases with an Oncolytic Herpes Virus Expressing Interleukin 12. Clinical Cancer Research, 10(1), 251-259. doi: 10.1158/1078-0432.ccr-0197-3
33. Stiles, B. M., Bhargava, A., Adusumilli, P. S., Stanziale, S. F., Kim, T. H., Rusch, V. W., Fong, Y. (2003). The replication-competent oncolytic herpes simplex mutant virus NV1066 is effective in the treatment of esophageal cancer. Surgery, 134(2), 357-364. doi: 10.1067/msy.2003.244
34. Cozzi, P. J., Burke, P. B., Bhargava, A., Heston, W. D., Huryk, B., Scardino, P. T., Fong, Y. (2002). Oncolytic viral gene therapy for prostate cancer using two attenuated, replication-competent, genetically engineered herpes simplex viruses. The Prostate, 53(2), 95-100.
Bhargava was misspelled in publication
Book Chapter
1. Bhargava, A., Keller, S. M. (2015). In Thoracoscopic Sympathectomy for Hyperhidrosis and Vasomotor Disorders (2nd ed.). Adult Chest Surgery.
2. Bhargava, A., Abbas, G., Landreneau, R. J. (2012). Radiofrequency Ablation of Lung Cancer. In Cardiothoracic Surgery Review.
3. Bhargava, A., Shuchert, M. J., Landreneau, R. J. (2012). Role of Esophageal Stents in the Management of Malignant and Benign Esophageal Strictures. In Cardiothoracic Surgery Review.
4. Fong, Y., Kim, T., Bhargava, A., Schwartz, L., Brown, K., Brody, L., Covey, A., Karrasch, M., Getrajdman, G., Mescheder, A., Jarnagin, W., Kemeny, N. (2009). In A herpes oncolytic virus can be delivered via the vasculature to produce biologic changes in human colorectal cancer (pp. 389-394). Molecular Therapy.
5. Bhargava, A., Fong, Y. (2004). In Viral-Based Therapies for Primary and Secondary Liver Cancer (2nd ed.). Malignant Liver Tumors: New and Emerging Therapies.
Licensures & Certifications
Minnesota State License (63315) February 2018 - Present
DEA Certification (FB0102513) 2018 - Present
NPI (1679796999) 2018 - Present
American Board of Surgery (059195) March 26, 2014 - Present
American Board of Thoracic Surgery (7822) June 2012 - Present
New York State Medical License (223783) 2002 - Present
Awards, Honors and Recognitions
Herbert B. Ward Excellence in Teaching Award, Division of Cardiothoracic Surgery — 2024
Presentations
Presentations
Invited Oral Presentations at International Professional Meetings, Conferences, etc.
Underline - indicates student presenter
- Bhargava, A. "Do All Patient Need Repair of a Giant Paraesophageal Hernia - When to Operate and Preferred Approach", ACS Clinical Congress 2023, ACS, United States. (October 2023). Presentation/Talk.
- Bhargava, A. "Management of Postoperative Air Leak", Asociación Latinoamericana de Tórax (ALAT) y del Comité Científico del 15° Congreso. (July 23, 2022). Presentation/Talk.
- Bhargava, A. "Lobectomy in octogenarians", VATS Quebec. (July 2019). Presentation/Talk.
- Rao, M. V., (Author & Presenter), Coughlan, A., (Author), Bhargava, A., (Author), Diaz Gutierrez, I., (Author), Small, J., (Author), Andrade, R. S., (Author) "Laparoscopic Diaphragm Plication for Unilateral Diaphragm Paralysis and Eventration: Long Term Reults", AATS 99th Annual Meeting, AATS, Toronto, Canada. (May 2019). Presentation/Talk.
- Su, C. T., Bhargava, A., Shah, C. D., Halmos, B., Gucalp, R. A., Packer, S. H., Ohri, N., Haramati, L. B., Perez-Soler, R., Cheng, H. "Screening Patterns and Mortality Differences in Patients with Lung Cancer at an Urban Underserved Community", IASLC, International Association for the Study of Lung Cancer (IASLC), Yokohama, Japan. (September 23, 2017). Presentation/Talk.
Invited Oral Presentations at National Professional Meetings, Conferences, etc.
Underline - indicates student presenter
- Bhargava, A., Schuchert, M. J., Wilson, D. O., Landreneau, R. J., Luketich, J. D., Christie, N. A. "Metastasectomy for Melanoma in the VATS Era", ASCO, American Society of Clinical Oncology, Orlando, Florida. (May 29, 2009). Abstract.
- Woo, Y., Reid, V., Yu, Z., Carlson, D., Bhargava, A., Wong, R., Fong, Y. "Oncolytic Herpes Simplex virus, NV1066 Detects Premalignant Lesions of the Oral Cavity and slows their progression to invasive squamous cell carcinoma", Society of Surgical Oncology 60th Annual Cancer Symposium. (March 15, 2007). Presentation/Talk.
- Stiles, B. M., Bhargava, A., Adusumilli, P., Stanziale, S. F., Kim, T. H., Rusch, V. W., Fong, Y. "An Oncolytic Herpes Simplex Mutant Expressing Green Fluorescent Protein is Effective in the Treatment and Localization of an Esophageal Cancer Cell Line", 64th Annual Meeting, Society of University Surgeons. (2003). Presentation/Talk.
- Stiles, B. M., Bhargava, A., Stanziale, S. F., Fong, Y. "Estrogen enhances efficacy of an oncolytic herpes simplex viral mutant in estrogen receptor positive breast cancer cells", 94th Annual Meeting, American Association for Cancer Research. (2003). Presentation/Talk.
- Bhargava, A., Stiles, B. M., Mullerad, M., DeRubertis, B. G., Stanziale, S. F., Kim, T. H., Adusumilli, P., Kim, T. H., Fong, Y. "An Oncolytic Herpes Virus Expressing Green Fluorescent Protein Localizes and Treats Urinary Bladder Cancer", Surgical Forum Program at the 89th Annual Clinical Congress Meeting of the American College of Surgeons. (October 19, 2003). Presentation/Talk.
- Bhargava, A., Stiles, B. M., Mullerad, M., Gusani, N. J., Adusumilli, P., Kim, T. H., Fong, Y. "Hormonal Milieu Enhances the Efficacy of Oncolytic Herpes Viral Therapy in Prostate Cancer", 6th Annual Meeting, The American Society of Gene Therapy. (June 4, 2003). Presentation/Talk.
- Stiles, B. M., Adusumilli, P., Bhargava, A., Stephen, S. F., Wong, R. J., Rusch, V. W., Fong, Y. "Minimally Invasive In Vivo Imaging Of An Oncolytic Herpes Simplex Virus Mutant Expressing Green Fluorescent Protein", 6th Annual Meeting, The American Society of Gene Therapy. (June 4, 2003). Presentation/Talk.
- Kim, T. H., Bhargava, A., Stiles, B. M., Wong, R. J., Fong, Y., Dannenberg, A. J. "Oncolytic Herpes Simplex Virus-1 G207 Induces Cyclooxygenase-2 Gene Expression by Activation of the Mitogen Activated Protein Kinase Pathway", 6th Annual Meeting, The American Society of Gene Therapy. (June 4, 2003). Presentation/Talk.
- DeRubertis, B. G., Stiles, B. M., Bhargava, A., Gusani, N. J., Fong, Y. "Cytokine Secreting Oncolytic Herpes Virus Effectively Treats Micrometastatic Liver Disease in a Murine Model", 5th Annual Meeting, The American Society of Gene Therapy. (2002). Presentation/Talk.
Invited Oral Presentations at Local and Regional Professional Meetings, Conferences, etc.
Underline - indicates student presenter
- Bhargava, A. "Adventures in Robotics: A Surgeon's Learning Curve", MHealth Fairview Grand Rounds, MHealth Fairview. (January 6, 2022). Lecture
- Bhargava, A. "Surgical Therapy for Hiatal Hernia", Fairview Ridges Hospital Grand Rounds, Fairview Ridges Hospital. (November 6, 2020). Presentation/Talk
Peer-Reviewed Oral Presentations at National Professional Meetings, Conferences, etc
Underline - indicates student presenter
- Diaz Gutierrez, I., Bhargava, A., Rao, M. V., Andrade, R. S. "Retrosternal Roux-en-Y Esophagojejunostomy for Delayed Esophageal Reconstruction", Society of Thoracic Surgeons 57th Annual Meeting. (January 2021). Presentation/Talk
Peer-Reviewed Oral Presentations at Local and Regional Professional Meetings, Conferences, etc
Underline - indicates student presenter
- Diaz Gutierrez, I., (Author & Presenter), P, A., (Author), Rao, M. V., (Author), Bhargava, A., (Author), Andrade, R. S., (Author) "The safety learning curve for uniportal VATS anatomic lung resection", Minnesota Surgical Society Fall Conference, ACS, Minneaapolis, United States. (October 2019).
Poster Abstract Presentations at Professional Meetings, Conferences, etc.
Underline - indicates student presenter
- Bhargava, A. "Esophageal Perforation After Anterior Cervical Spine Surgery: An Evolution of an Approach", Society of Thoracic Surgeons 57th Annual Meeting. (January 2021). Poster
- Diaz Gutierrez, I., (Author), Robbins, A., (Author & Presenter), Zhang, B., (Author), Bhargava, A., (Author), Rao, M. V., (Author), Andrade, R. S., (Author) "Long Term Results of Diaphragm Hernia Repair After LVAD Explant and Heart Transplant", 56th Annual Meeting, The Society of Thoracic Surgeons, New Orleans, Louisiana, United States. (January 2020). Poster
- Diaz Gutierrez, I., (Author), Rao, M., Bhargava, A., Andrade, R. "Laparoscopic Transgastric Esophageal Mucosectomy (LTEM); From Lab TO OR", AATS International Thoracic Surgical Oncology Summit, AATS, New York, New York. (September 2019). Poster
- Wafi, A., (Author), Andrade, R., Olejniczak, M., Bhargava, A., Diaz-Gutierrez, I., Rao, M., (Author & Presenter) "Non-Intubated Thoracic Surgery: A Single-Center Experience", AATS International Thoracic Surgical Oncology Summit, New York, New York. (September 2019). Poster
Professional Memberships
Thoracic Surgery Directors Association Finance Committee (TSDA)
Thoracic Surgery Directors Association In-Training Exam Committee (TSDA)
Thoracic Surgery Directors Association Thoracic Education Cooperative Group (TSDA)
European Society of Thoracic Surgeons (ESTS)
General Thoracic Surgery Club (GTSC)
International Association for the Study of Lung Cancer (IASLC)
International Society for Diseases of the Esophagus (ISDE)
New York State Thoracic Society (NYSTS)
The Society of Thoracic Surgeons (STS)
candidate member: 2009-2013
Society of Laparoendoscopic Surgeons (SLS)
Candidate Group, American College of Surgeons
Golden Key National Honor Society
The Honor Society of Phi Kappa Phi
The Iron Cross Society