Kara Heinle | [email protected]
B172 Mayo, MMC 195
420 Delaware St SE
Minneapolis, MN 55455
Javier Navarro Rueda, PhD, is a Assistant Professor in the Department of Surgery, at the University of Minnesota. He serves as Assistant Professor for the Visible Heart®️ Laboratories. He earned his Bachelor of Engineering in Mechanical Engineering and his MSc in Mechanical Engineering from Universidad de los Andes (Bogotá, Colombia), and then his PhD in Bioengineering from the University of Maryland (MD, USA) as a Fulbright Fellow.
His postdoctoral training included research at the University of Rochester (NY, USA) on the scarless-to-scarred wound healing transition in embryo animal models; the research program for the diagnosis, training, logistics, education, organization and monitoring of patients with congenital heart disease at Universidad de los Andes (Bogotá, Colombia); and the design, development, and consolidation of a clinic-driven 3D technology center to provide clinicians, patients, and researchers with computational modeling, simulation, and 3D printed models to be used in complex surgical planning, practice, and decision-making at Fundación Cardioinfantil - Instituto de Cardiología (Bogotá, Colombia). He has been a researcher, teacher, and advisor at Universidad de los Andes (Bogotá, Colombia), University of Maryland (MD, USA), University of Rochester (NY, USA), and Pontificia Universidad Javeriana (Bogotá, Colombia), where he also served as Director for the Mechanical Engineering Program.
Postdoctoral Fellow, Universidad de Los Andes (Bogotá, Colombia) and Fundación Cardioinfantil - Instituto de Cardiología (Bogotá, Colombia), 2022
Postdoctoral Associate, University of Rochester (Rochester, NY, USA), 2020
PhD in Bioengineering, University of Maryland (College Park, MD, USA), 2019
MSc in Mechanical Engineering, Universidad de Los Andes (Bogotá, Colombia), 2012
Bachelor of Engineering in Mechanical Engineering, Universidad de Los Andes (Bogotá, Colombia), 2011
CE Pérez, C Vargas, J Sánchez, C Castro, R Gutiérrez, JF Forero, JM Pérez, JC Briceño, HM Medina, JP Umaña, J Navarro, CE Guerrero: "Surgical planning aided with 3D technologies for management of complex paracardiac tumors". Journal of Cardiothoracic Surgery, Vol 19:548, 2024. PMID: 39342312, DOI: 10.1186/s13019-024-03096-w.
J Navarro*, A Korcari*, P Nguyen, I Bah, A AlKhalifa, S Fink, M Buckley, CK Kuo. “Method Development and Characterization of Chick Embryo Tendon Mechanical Properties”. Journal of Biomechanics, Vol. 133, pp. 110970, 2022. PMID: 35123205, DOI: 10.1016/j.jbiomech.2022.110970. (*equal contributors)
M Pineda, LL Cárdenas, J Navarro, DM Sánchez-Palencia, RdP López-Panqueva, JM Pérez, JC Briceño: “Prevention of Bleeding After Percutaneous Biopsy with a Small Intestinal Submucosa Hemostatic Plug”. Acta Biomaterialia, Vol. 137, pp. 103-111, 2022. PMID: 34687955. DOI: 10.1016/j.actbio.2021.10.025.
M Kimicata, J Allbritton-King, J Navarro, M Santoro, T Inoue, N Hibino, JP Fisher: "Assessment of Decellularized Pericardial Extracellular Matrix (ECM) and Poly(propylene fumarate) (PPF) Biohybrid for Small-Diameter Vascular Graft Applications". Acta Biomaterialia, Vol. 110, pp. 68–81, 2020. PMID: 32305447. DOI: 10.1016/j.actbio.2020.04.013.
J Navarro, RM Clohessy, RC Holder, AR Gabard, GJ Herendeen, RJ Christy, LR Burnett, JP Fisher, “In Vivo Evaluation of 3D Printed, Keratin-Based Hydrogels in a Porcine Thermal Burn Wound Model”. Tissue Engineering Part A, Vol. 26, Num. 5 and 6, pp. 265-278, 2020. DOI: 10.1089/ten.tea.2019.0181. PMID: 31774034.
J Navarro, J Swayambunathan, M Janes, M Santoro, AG Mikos, JP Fisher, “Dual-Chambered Membrane Bioreactor for Co-Culture of Stratified Cell Populations”. Biotechnology and Bioengineering J., Vol. 116, pp. 3253-3268, 2019. PMID: 31502660. DOI: 10.1002/bit.27164.
J Navarro, M Din, M Janes, JP Fisher, ML Dreher: “Effect of Print Orientation on Microstructural Features and Mechanical Properties of Porous Structures”. Rapid Prototyping J., Vol. 25 No. 6, pp. 1017-1029, 2019. DOI: 10.1108/RPJ-10-2018-0276.
JR Yu, J Navarro, JC Coburn, B Mahadik, J Molnar, JH Holmes IV, AJ Nam, JP Fisher: "Current and Future Perspectives on Skin Tissue Engineering: Key Features of Biomedical Research, Translational Assessment, and Clinical Application". Advanced Healthcare Materials, 8, 1801471, 2019. PMID: 30707508. DOI: 10.1002/adhm.201801471.
J Navarro, J Swayambunathan, MJ Lerman, M Santoro, JP Fisher: “Development of Keratin-Based Membranes for Potential Use in Skin Repair”. Acta Biomaterialia, Vol. 83, pp. 177-188, 2019. PMID: 30342286. DOI: 10.1016/j.actbio.2018.10.025.
JK Placone, J Navarro, GW Laslo, MJ Lerman, AR Gabard, GJ Herendeen, EE Falco, S Tomblyn, L Burnett, JP Fisher: “Development and Characterization of a 3D Printed, Keratin-Based Hydrogel”. Annals of Biomedical Engineering, Vol. 45, No. 1, pp. 237-248, 2017. PMID: 27129371. DOI: 10.1007/s10439-016-1621-7.
Materials for the development and assessment of novel biomedical devices for cardiovascular applications (engineering design, device development, prototyping and evaluation, animal models, pre-clinical and clinical evaluation) – Past and current developments include synthetic 3D printed models of the RVOT for pulmonary valve studies, ECM-based vascular grafts (abdominal aortic aneurism, hemodialysis shunts, small diameter venous grafts, aortic/pulmonary valve leaflets), hemostatic collagen plug for percutaneous biopsies, and regenerative 3D-scaffolds for dermal applications.
Biomaterials for the development of bioreactors for understanding and assessment of tissues, organs, engineered constructs, and biomedical devices - Past and current cases include vascular, tendon, stratified dermis, stratified endometrium, stratified cartilage, and biliary duct bioreactors.
- Development of bioinks, bioprinting, and 3D printing-based tissue engineering.
- 3D printing, sustainable uses of 3D printing, and recycling of 3D printed materials.
- Uses and evaluation of 3D technologies in education, engineering, and medicine.
Regenerative medicine and understanding of scarring and scarless healing pathways – current application in musculoskeletal applications (embryonic tendon wound formation and regeneration), and applications in prenatal congenital heart treatments and surgery.
Optimization and sustainable transitioning from animal models – Past and current experience include large ovine and porcine models, small leporid and murine models, and chick embryo developmental model.