Nolan C. Cirillo-Penn, MD, RPVI

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Nolan C. Cirillo-Penn, MD, RPVI

Assistant Professor, Division of Vascular Surgery

Associate Program Director, Vascular Surgery Fellowship and Integrated Residency

[email protected]

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Assistant Professor, Division of Vascular Surgery

Associate Program Director, Vascular Surgery Fellowship and Integrated Residency

Administrative Contact

Meagan Seubert | [email protected] | 612-625-1485

Address

420 Delaware St. SE, MMC 195
Minneapolis, MN 55455

Biography

Dr. Cirillo-Penn is focused on the open surgical and endovascular treatment of aneurysms, dissections of the aorta, including complex abdominal, thoracoabdominal and aortic arch aneurysm. His passion for aortic surgery stems from his training at Mayo Clinic under Drs. Thomas Bower, Gustavo Oderich, and Bernardo Mendes. He is also interested in prediction and treatment of mesenteric ischemia. Dr. Cirillo-Penn is a committed academic surgeon with a passion for aortic and mesenteric research as well as the education of future vascular surgeons. During his training, Dr. Cirillo-Penn received multiple honors, including the D. Emerick Szilagyi Award for Most Outstanding Clinical Research from the Midwestern Vascular Surgical Society, the Peter Gloviczki, M.D. Research and Academic Award, and the 2022–2023 Clinical and Teaching Award—both presented by the Mayo Clinic Division of Vascular and Endovascular Surgery.

Education

Graduate School

Integrated Vascular Surgery, 2018 - 2023, Mayo Clinic School of Graduate Medical Education

Medical School

MD, Rutgers Robert Wood Johnson Medical School, 2018

Residency

Residency, Vascular and Endovascular Surgery, Mayo Clinic

Additional Details

BA, Cum laude, Colgate University

Publications

Selected Publications

Cirillo-Penn, N. C., Bower, T. C., Oderich, G. S., Mendes, B. C. (2025). Vascular video ipsilateral hybrid repair of a combined type IB and III endoleak after fenestrated-branched endograft and bilateral iliac branch endoprosthesis. Journal of Vascular Surgery Cases, Innovations and Techniques, 11(5), 101870. doi: 10.1016/j.jvscit.2025.101870
Doenges, J. E., Watt, T. M.F., Huddleston, S. J., Cirillo-Penn, N. C. (2025). Contemporary Application of a Hybrid Iliofemoral Conduit for Second-Stage Endovascular Repair of a Penetrating Ulcer of the Aortic Arch with Subacute Contained Rupture. Journal of Vascular Surgery, 81(5), S59. doi: 10.1016/j.jvs.2025.01.140
Dong, E. K., German, Z., Cirillo-Penn, N. C. (2025). Utilization of Multiple Endovascular Techniques to Achieve Seal in the Treatment of a Rapidly Enlarging Post-Dissection Thoracic Aortic Aneurysm. Journal of Vascular Surgery, 81(5), S59-S60. doi: 10.1016/j.jvs.2025.01.141
Cirillo-Penn, N. C., MacArthur, T. A., Tenorio, E. R., DeMartino, R. R., Macedo, T. A., Oderich, G. S., Mendes, B. C. (2025). Outcomes of Patients Treated with Double-Wide Scallop vs Fenestrations for Celiac Artery Incorporation During Repair of Complex Abdominal Aortic Aneurysms. Journal of Vascular Surgery, 81(5). PMID: 39884565 doi: 10.1016/j.jvs.2025.01.194
Tabiei, A., Cirillo-Penn, N. C., DeMartino, R. R., Oderich, G. S., Mendes, B. C. (2025). Seventy-seven-year-old man with large endoleak status post fenestrated-branched endovascular aortic repair. Journal of Vascular Surgery Cases, Innovations and Techniques, 11(2), 101691. PMID: 39811744 PMCID: PMC11730557 doi: 10.1016/j.jvscit.2024.101691 UNIVERSITY OF MINNESOTA HEALTH SCIENCES CV UPDATED: FEBRUARY 12, 2026 5
Rodrigues, D. V.S., Chait, J., Cirillo-Penn, N. C., DeMartino, R. R., Vierkant, R. A., Oderich, G. S., Mendes, B. C. (2024). Trends in hospitalization of patients undergoing endovascular treatment of thoracoabdominal aortic aneurysms based on cerebrospinal fluid drainage strategy. Journal of Vascular Surgery, 80(4), 988-995.e1. doi: 10.1016/j.jvs.2024.05.032
Kahng, M. W., Cirillo-Penn, N. C., Huddleston, S. J., Wang, Q., Shaffer, A. W., Tarbunou, Y. A., Kelly, R. F., Faizer, R. (2024). People of Hmong Ethnicity Have Increased Predisposition to Aortic Dissection. Journal of Vascular Surgery, 80(3), e64-e65. doi: 10.1016/j.jvs.2024.06.110
Cifuentes, S., Cirillo-Penn, N. C., Breite, M. D., Rasmussen, T. E. (2024). Hybrid repair of tandem high-grade innominate and carotid artery stenosis in an asymptomatic male. Journal of Vascular Surgery Cases, Innovations and Techniques, 10(3), 101487. doi: 10.1016/j.jvscit.2024.101487
Cirillo-Penn, N. C., Mendes, B. C., MacArthur, T. A., Perry, R. J.T., Oderich, G. S. (2024). Parallel intercostal artery stenting and exclusion of symptomatic bucket-handle intercostal patch aneurysm. Journal of Vascular Surgery Cases, Innovations and Techniques, 10(3), 101486. doi: 10.1016/j.jvscit.2024.101486
Cirillo-Penn, N., Zheng, X., Mao, J., Johnston, L., D'Oria, M., Scali, S., Goodney, P., DeMartino, R. (2023). Long Term Mortality and Reintervention Following Repair of Ruptured Abdominal Aortic Aneurysms using VQI Matched Medicare Claims. Annals of Surgery, 278(5), e1135.

Research

-IMPROVE-AD: NIH NHLBI sponsored Randomized Control Trial of uncomplicated Type B Aortic Dissection without rupture or malperfusion. Role: Site Primary Investigator

-TAMBE PAS: Post-Approval Registry for patients with pararenal and thoracoabdominal aortic aneurysms treated with the ThoracoAbdominal MultiBranch Endoprosthesis . Role: Site Primary Investigator

-Complex open and endovascular repair of aortoiliac, thoracoabdominal and aortic arch aneurysms and dissections

-Fenestrated-branched endovascular aortic repair

-Natural history and treatment of mesenteric ischemia

-Hemodynamic implications and manifestations of aortic disease

-Device design and innovation

Licensures & Certifications

The American Board of Surgery (Vascular Surgery #104261) 2024 - Present

Registered Physician in Vascular Interpretation 2021 - Present

MN Medical License (65817) 2019 - Present

NPI (1093210262) 2018 - Present

USMLE - Step 2 CK - passed 2017 - Present

USMLE - Step 2 CS - passed 2017 - Present

USMLE - Step 1 - passed 2016 - Present

DEA (FC8640016) 2019

Awards, Honors and Recognitions

JVS-CIT Reviewer of the Year Award, Journal of Vascular Surgery Cases, Innovations, and Techniques 2024

JVS-VL Rising Star Reviewer of the Year Award, Journal of Vascular Surgery Venous and Lymphatic Disorders 2023

Thomas C. Bower M.D. Clinical and Teaching Award, Mayo Clinic Division of Vascular and Endovascular Surgery 2023

D. Emerick Szilagyi Award for Most Outstanding Clinical Research, Midwestern Vascular Surgical Society 2022

Peter Gloviczki, M.D. Research and Academic Award, Mayo Clinic Division of Vascular and Endovascular Surgery 2022

Mayo Clinic Bronze Quality Certification 2018

Eastern Vascular Society Travel Grant 2017

Nathaniel B. Stanton Fellowship Award - Career in Medicine Merit Scholarship 2014

Employee of the Month, Centerplate, Somerset Patriots Ballpark 2011

Presentations

Cirillo-Penn, N. C., DeMartino, R. R., Rasmussen, T. E., Shuja, F., Colglazier, J. J., Kalra, M., Olderich, G. S., Mendes, B. C. "Midterm Clinical Outcomes of Retrograde Open UNIVERSITY OF MINNESOTA HEALTH SCIENCES CV UPDATED: FEBRUARY 12, 2026 9 Mesenteric Stenting For Mesenteric Ischemia", Mayo Clinic Balfour Surgery Research Symposium. (November 2022). Poster.
Kim, K., Huntress, L., Lee, K., Cirillo-Penn, N. C., Kwon, C., Truong, H., Balica, A., Beckerman, W. "Transradial versus Transfemoral Approach to Uterine Artery Embolization for Uterine Fibroids", 36st EVS Annual Meeting, Eastern Vascular Society, Philadelphia, Pennsylvania. (September 2022). Poster.
Kenyon, B., Cirillo-Penn, N. C., Chait, J., Stockland, A., Bakkum-Gamez, J., Colglazier, J. J. "Multidisciplinary hybrid management of uterine leiomyoma with multiple arteriovenous fistulae causing high output cardiac state in the setting of Reed syndrome", 46th Annual Meeting, Midwestern Vascular Surgery Society, Grand Rapids, Michigan. (September 2022). Poster.
Cirillo-Penn, N. C., Zheng, X., Mao, J., Mendes, B. C., D'Oria, M., Scali, S. T., Goodney, P. P., DeMartino, R. R. "Long Term Mortality and Reinterventions Following Repair of Ruptured Abdominal Aortic Aneurysms using VQI Matched Medicare Claims", 2022 Vascular Annual Meeting, Society for Vascular Surgery, Boston, Massachusetts. (June 2022). Poster.
MacArthur, T. A., Goswami, J., Ferrara, M. J., Anderson, J., Zietlow, J., Cirillo-Penn, N. C., Spears, G. M., Bailey, K. R., Loomis, E. A., Erben, Y. M., Sridharan, M., Hurt, R. T., Ganesh, R., Heller, S. F., Park, M. S. "Thrombin Generation Kinetics in COVID-19 Breakthrough Infection After Vaccination", 45th Annual Conference on Shock, Shock Society, Toronto, Canada. (June 2022). Poster.
Khalifeh, A. H., Cirillo-Penn, N. C., Rasmussen, T. E., Colglazier, J. J., Shuja, F., Mendes, B. C., DeMartino, R. R. "Bilateral Iliac Branch Endoprosthesis for Bilateral Iliac Artery Aneurysms", 2022 SCVS Annual Symposium, Society for Clinical Vascular Surgery, Las Vegas, Nevada. (March 2022). Poster.
Cirillo-Penn, N. C., Pochettino, A., Khalifeh, A. H., Colglazier, J. J., Shuja, F., Oderich, G. S., Bower, T. C. "Use of Low-Flow Cardiopulmonary Bypass For Repair Of Complex Abdominal Aortic Aneurysms With Relative Contra-Indications To Aortic Cross Clamp", 2022 SCVS Annual Symposium, Society for Clinical Vascular Surgery, Las Vegas, Nevada. (March 2022). Poster.
Rogers, R. T., Lemmens, C., Farazdaghi, A., Cirillo-Penn, N. C., Mees, B., Tenorio, E. R., Schurink, G. H., DeMartino, R. R., Oderich, G. S., Mendes, B. C. "Fenestrated/Branched Endovascular Aortic Repair Usin Unilateral Femoral Access in Patients with Unilateral Iliac Occlusive Disease", 2021 Vascular Annual Meeting, Society for Vascular Surgery, San Diego, California. (August 2021). Poster.
Cirillo-Penn, N. C., Sen, I., Young, W. F., Kasperbauer, J. L., Bower, T. C. "Clinical Outcomes of Patients With Recurrent Paragangliomas After Resection of Carotid Body Tumors", 2019 Vascular Annual Meeting, Society for Vascular Surgery, National Harbor, Maryland. (June 2019). Poster.
Cirillo-Penn, N. C., Branco, B., Browder, R., Kougias, P., Mills, J. L. "Contemporary Application of Splenorenal Transposition in Renal Preservation During Repair of an Aortic Graft-Enteric Erosion", 33rd TSVES Annual Meeting, Texas Society for Vascular and Endovascular Surgery, Dallas, Texas. (November 2017). Poster.

Professional Memberships

Vascular and Endovascular Surgery Society 2023 - Present

Midwestern Vascular Surgery Society 2022 - Present

Society For Clinical Vascular Surgery 2022 - Present

Alliance for Physician Certification & Advancement 2021 - Present

Co-Founder and Resident Liaison, Mayo Alix SOM Vascular Surgery Interest Group 2021 - Present

Senior Liaison, Vascular Surgery Social Media 2019 - Present

American College of Surgeons 2018 - Present

Vascular and Endovascular Surgery Residency Program Evaluation Committee 2018 - Present

Society of Vascular Surgery 2016 - Present

Clinical Summary

-Open and endovascular repair of aortic aneurysms and dissections

-Complex endovascular repair of aortoiliac, thoracoabdominal and aortic arch aneurysms using fenestrated and branched stent grafts

-Mesenteric arterial reconstruction for mesenteric ischemia

-Renal Arterial Reconstruction

-Cerebrovascular and supra-aortic trunk recontruction

-Peripheral arterial disease

-Reconstruction of the Superior and Inferior Vena Cava for benign and malignant disease

-Vascular reconstruction in oncologic surgery