Dr. Pruett began his clinical career at the University of Virginia rising from Assistant Professor of Surgery (1987) to Professor of Surgery and Division Chief of Transplantation Surgery by 1996. He was appointed the Strickler Family Professor of Transplantation in 1997. He was the Program Director of the transplantation training program at University of Virginia. As an intensivist, he was co-director of the surgical ICU and established and was Program Director of the Critical Care Training program. In 2009, he moved to the University of Minnesota as Professor of Surgery and Internal Medicine.
Dr. Pruett is Past-President of American Society of Transplant Surgeons (2016-2017) and previously served as Treasurer of American Society of Transplant Surgeons’ Council (2012-2015). He has served on and chaired various committees within the ASTS and AST and has spoken broadly on legal and system issues that impact to organ transplantation within global healthcare systems. Dr. Pruett was President of United Network for Organ Sharing (2008-2009); Chair of the Membership and Professional Standards Committee (2007- 2008) and has represented UNOS in multiple international initiatives.