Intramural Pediatric Research Seminar Series (IMPRESS)

The Intramural Pediatric Research Seminar Series (IMPRESS) provides an opportunity to discover the wide variety of amazing cutting edge, interdisciplinary and collaborative work being done across the Department of Pediatrics. This event will occur on the last Tuesday of every month.

Topic: Mitochondrial function in Netrin1/DCC- regulated neurodevelopment

Dysfunction of mitochondria during fetal and child development has been increasingly recognized to be responsible for neurodevelopmental and psychiatric disorders. Our recent studies have revealed potential regulation of mitochondrial activity by the Netrin1/DCC (Deleted in Colorectal Carcinoma) signaling, which has critical functions during neurodevelopment and its dysregulation underlies some common disorders with mitochondrial dysregulation (e.g., developmental delay , schizophrenia, and autism spectrum disorder), . We will present our basic science research, supported by a Masonic Cross- Departmental Grant award, showing that mitochondrial activity contributes to Netrin-1/DCC regulation of neuronal development. We will further discuss novel research directions in the Bastian and Chen labs stimulated by this award.

Speakers: 

Thomas Bastian, PhD
Assistant Professor
Division of Neonatology

Tim Monko, PhD
Post-Doctoral Researcher
Bastian Lab

Zhe Chen, PhD
Assistant Professor
Department of Neuroscience

Audience: Department of Pediatrics Faculty & Staff
Location: Health Sciences Education Center Room 2-132 or via Zoom

To have the calendar invite and Zoom link added to your calendar, please submit the request here: https://z.umn.edu/PedsIMPRESS