Panoskaltsis-Mortari Laboratory

The Panoskaltsis-Mortari Laboratory is centered on the field of regenerative medicine, which includes Tissue-Organ Engineering and Biofabrication. We study tissue engineering from stem cells using two approaches:

1. 3D Bioprinting using extrusion, suspension, and laser-digital photopolymerization and electrospinning technologies. Current projects aim to create lung models, trachea, esophagus and muscle for transplantation, and 3D cancer models to evaluate drugs and cell therapies.
2. Wetspinning of prealigned cells.

Within these projects are studies on the role of extracellular matrix composition and mechanical properties in driving appropriate cell differentiation, and exploration of new strategies to vascularize bioengineered tissue. As this is highly interdisciplinary research, we accept students with various interests ranging from biomedical engineering, physiology, stem cell biology, robotics, mechanical engineering, biomaterials science, and surgery. We also use automation to build bioreactors to house biofabricated constructs.

Want to learn in our lab?

We are accepting undergraduate students to assist in the lab.