Janet Hume

Associate Professor, Division of Pediatric Critical Care Medicine
Faculty, Department of Pediatrics


Dr. Hume is an Associate Professor of Pediatrics in the Division of Pediatric Critical Care. She received her MD and PhD (Microbiology) at the University of Iowa Carver College of Medicine. She then underwent residency training in pediatrics at the University of Arkansas for Medical Sciences, and fellowship training in pediatric critical care at the University of Texas Southwestern Medical Center.
Her research and clinical interests include sepsis and other pathophysiologic processes involving a dysregulated inflammatory/immune response. Dr. Hume's research projects have included studying myocardial dysfunction in community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) sepsis in a mouse model. She has also been involved as local PI in several multicenter studies through the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) network. These studies include Sepsis Prevalence, Outcomes and Therapies (SPROUT); Pathogen Identification in Pediatric Hematopoietic Stem Cell Transplant Patients with Suspected Lower Respiratory Tract Infection; Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE); and Sepsis-induced Red Cell Dysfunction (SiRD).
Dr. Hume is part of the team running the Special Pathogens Unit (SPU) at the University of Minnesota Medical Center, one of 10 Regional Ebola and Special Pathogens Treatment Centers in the US. These centers were established as part of the response to the West African Ebola epidemic as a resource for treating patients with Ebola virus and other high consequence infectious diseases. She has also been involved with the development of the Special Pathogens Research Network, which is intended to facilitate clinical and basic research on high consequence infectious diseases among the 10 regional treatment centers.

Research Summary

Sepsis; systemic inflammatory response syndrome (SIRS); inflammatory response; acute respiratory distress syndrome (ARDS)/acute lung injury (ALI); MRSA infection, pathophysiology, and epidemiology; high consequence infectious diseases (particularly impact on pediatric populations).

Clinical Summary

Sepsis epidemiology, recognition, treatment and outcomes; acute respiratory distress syndrome (ARDS)/acute lung injury (ALI) epidemiology, treatment and outcomes; improving treatment and outcomes for hematopoietic stem cell transplant (HSCT) patients in PICU; epidemiology, treatment and outcomes of pediatric patients with high consequence infectious diseases.


MD, University of Iowa Carver College of Medicine, Iowa City, IA
PhD in Microbiology, University of Iowa Carver College of Medicine, Iowa City, IA

Fellowships, Residencies, and Visiting Engagements

Residency in Pediatrics,
University of Arkansas for Medical Sciences
Little Rock, Arkansas, United States
Fellowship in Pediatric Critical Care,
University of Texas Southwestern Medical Center
Dallas, Texas, United States

Licensures and Certifications

Pediatrics, American Board of Pediatrics
Pediatric Critical Care Medicine, American Board of Pediatrics

Honors and Recognition

Minneapolis - St. Paul “Top Doctors, Rising Star Edition” , Minneapolis - St. Paul Magazine



Pediatric Critical Care Medicine
Academic Office Building
2450 Riverside Ave S AO-301
Minneapolis, MN 55454

Administrative Contact

Joanna Perrier
Administrative Phone: 612-625-6678
Administrative Email: jperrier@umn.edu