Dr. Hume is an Associate Professor of Pediatrics in the Division of Pediatric Critical Care. She received her MD and PhD (Microbiology) at the University of Iowa Carver College of Medicine. She then underwent residency training in pediatrics at the University of Arkansas for Medical Sciences, and fellowship training in pediatric critical care at the University of Texas Southwestern Medical Center.
Her research and clinical interests include sepsis and other pathophysiologic processes involving a dysregulated inflammatory/immune response. Dr. Hume's research projects have included studying myocardial dysfunction in community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) sepsis in a mouse model. She has also been involved as local PI in several multicenter studies through the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) network. These studies include Sepsis Prevalence, Outcomes and Therapies (SPROUT); Pathogen Identification in Pediatric Hematopoietic Stem Cell Transplant Patients with Suspected Lower Respiratory Tract Infection; Pediatric Acute Respiratory Distress Syndrome Incidence and Epidemiology (PARDIE); and Sepsis-induced Red Cell Dysfunction (SiRD).
Dr. Hume is part of the team running the Special Pathogens Unit (SPU) at the University of Minnesota Medical Center, one of 10 Regional Ebola and Special Pathogens Treatment Centers in the US. These centers were established as part of the response to the West African Ebola epidemic as a resource for treating patients with Ebola virus and other high consequence infectious diseases. She has also been involved with the development of the Special Pathogens Research Network, which is intended to facilitate clinical and basic research on high consequence infectious diseases among the 10 regional treatment centers.