RHEUM-LOVE

Rheum-LOVE - longitudinal characterization of the role of the mucosal virome and microbiome in juvenile idiopathic arthritis (JIA) flares
Respiratory illnesses, including ear and sinus infections, colds, and pneumonias, are among the most common infectious diseases affecting children and adults across their lifespan. These diseases can be caused by many different types of microbes—bacteria, viruses and fungi—and different types of microbes may require different kinds of treatment. Respiratory illnesses may also cause flares of juvenile idiopathic arthritis (JIA).
This study is about learning more about the specific microbes that cause respiratory infections in children with JIA and whether those microbes cause JIA flares.
Another goal of this study is to learn about how infections may affect children with JIA differently than children without arthritis.
To conduct this research, we are inviting children ages 7 or younger who have JIA to participate. If the child with JIA has a sibling without a chronic disease who is age 7 or younger, we will also invite them to participate.
Interested in Participating?
QUESTIONS ABOUT THIS STUDY?: Contact our research team at [email protected]
What?
At home weekly nasal sample collection (for 26 weeks) from children under age 7 diagnosed with JIA and, if applicable, their siblings.
Completion of weekly online surveys (for 32 weeks).
Who?
Children under the age of 7 who have JIA are invited to participate.
If the child with JIA has a sibling without a chronic disease who is under the age of 7, we will also invite them to participate.
Where?
All nasal collections can be collected at home and subsequently mailed back to the study team with provided supplies and postage.
Why?
To learn more about the specific microbes that cause respiratory infections in children with JIA and whether those microbes cause JIA flares.
To learn about how infections may affect children with JIA differently than children without arthritis.
Compensation?
You will receive $5 per household for the paired survey and swab collection(s).
To learn about how infections may affect children with JIA differently than children without arthritis.