Ashish Gupta, MBBS, MPH

Dr. Gupta's primary interest focuses on early detection and developing effective cell and gene therapy interventions for children with inherited metabolic diseases. Current treatment strategies for these children include use of hematopoietic stem cell transplant as a means to either deliver enzyme as in lysosomal storage disorders or modify an uninhibited immune response as in cerebral adrenoleukodystrophy (ALD). He is also investigating autoimmune response of the host post hematopoietic stem cell transplant and ways to improve conditioning regimen and immune prophylaxis to control this effect, especially in children with inherited metabolic disorders. Additional research conducted by Dr. Gupta focuses on developing a registry and bio-specimen bank for patients with inherited metabolic diseases.