Radha Rajasingham, MD

Assistant Professor of Medicine, Division of Infectious Diseases and International Medicine

Radha Rajasingham

Contact Info

Mailing Address:
689 SE 23rd Avenue
MC2821 Room 4-105
Microbiology Research Facility
Minneapolis, MN 55455

Administrative Assistant Name
Tai McLaughlin

Administrative Phone

Administrative Email

Administrative Fax Number

Assistant Professor of Medicine, Division of Infectious Diseases and International Medicine

Cryptococcal Meningitis, HIV

Medical School, University of Minnesota, Minneapolis, MN

Residency, Beth Israel-Deaconess Medical Center, Boston, MA

Fellowship, Beth Israel-Deaconess Medical Center, Boston, MA


Awards & Recognition

  • Mpls.St.Paul Magazine 2020 Recognizes “Top Doctors: Rising Stars
  • Young Physician Scientists Award, American Society for Clinical Investigation (2020)


Research Summary/Interests

  • Implementation and Cost-effectiveness of Point-of-care Diagnostics
  • Cryptococcal Screening and Prevention
  • Cryptococcal Meningitis

Research Projects

Title: Evaluation of CRAG Screening with Enhanced Antifungal Therapy for Asymptomatic CRAG-Positive Persons

This study aims to determine if enhanced antifungal therapy improves survival in asymptomatic CRAG positive persons, and the cost-effectiveness of such a strategy.

Role: Principal Investigator

(K23AI138851-01, NIH, NIAID)


  • Rajasingham R, Smith RM, Park BJ, Jarvis JN, Govender NP, Chiller TM, Denning DW, Loyse A, Boulware DR. Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis. Lancet Infect Dis. 2017 Aug;17(8):873-881. doi: 10.1016/S1473-3099(17)30243-8. Epub 2017 May 5. PMID: 28483415; PMCID: PMC5818156.
  • Rajasingham R, Bangdiwala AS, Nicol MR, Skipper CP, Pastick KA, Axelrod ML, Pullen MF, Nascene AA, Williams DA, Engen NW, Okafor EC, Rini BI, Mayer IA, McDonald EG, Lee TC, Li P, MacKenzie LJ, Balko JM, Dunlop SJ, Hullsiek KH, Boulware DR, Lofgren SM; COVID PREP team. Hydroxychloroquine as Pre-exposure Prophylaxis for Coronavirus Disease 2019 (COVID-19) in Healthcare Workers: A Randomized Trial. Clin Infect Dis. 2021 Jun 1;72(11):e835-e843. doi: 10.1093/cid/ciaa1571. PMID: 33068425; PMCID: PMC7665393.
  • Nalintya E, Meya DB, Lofgren S, Huppler Hullsiek K, Boulware DR, Rajasingham R. A Prospective Evaluation of a Multisite Cryptococcal Screening and Treatment Program in HIV Clinics in Uganda. J Acquir Immune Defic Syndr. 2018 Jun 1;78(2):231-238. doi: 10.1097/QAI.0000000000001669. PMID: 29509588; PMCID: PMC5953806.
  • Rajasingham R, Meya DB, Greene GS, Jordan A, Nakawuka M, Chiller TM, Boulware DR, Larson BA. Evaluation of a national cryptococcal antigen screening program for HIV-infected patients in Uganda: A cost-effectiveness modeling analysis. PLoS One. 2019 Jan 10;14(1):e0210105. doi: 10.1371/journal.pone.0210105. PMID: 30629619; PMCID: PMC6328136.



  • Infectious Disease
  • Internal Medicine


Delaware Street Clinic (Infectious Disease/HIV Clinic)

Board Certifications

  • Internal Medicine
  • Infectious Diseases

Clinical Interests

HIV; PREP; Global Health