Clinical Studies
Advanced Endoscopy
Diabetes RElated to Acute pancreatitis and its Mechanisms (DREAM)
Prinicpal Investigator: Guru Trikudanathan
Currently Recruiting
Description: The purpose of this research study is to find out how many people with acute pancreatitis develop diabetes. Risk factors for diabetes and the types of diabetes that occur after acute pancreatitis will also be studied.
Luminal
Real-Time Feedback (RTFB) to Improve Colonoscopy
Prinicpal Investigator: Piet de Groen
Currently Recruiting
RPC01-3202: Induction Study #2 - A phase 3, multicenter, randomized, double-blind, placebo-controlled study of oral ozanimod as induction therapy for moderately to severely active crohn’s disease
Prinicpal Investigator: Eugenia Shmidt
Currently Recruiting
Description: This is a Phase 3, randomized, double-blind, placebo-controlled study to determine the effect of oral ozanimod as an induction treatment for subjects with moderately to severely active CD, defined as a CDAI score ≥ 220 to ≤ 450.
UP0085: A postmarketing, multicenter, longitudinal, prospective, pharmacokinetic, phase 1B study in pregnant women with chronic inflammatory diseases treated with cimzia (certolizumab pegol)
Prinicpal Investigator: Eugenia Shmidt
Currently Recruiting
Description: A postmarketing, multicenter, longitudinal, prospective, pharmacokinetic, phase 1B study in pregnant women with chronic inflammatory diseases treated with cimzia
A novel Peptamen-based enteral nutrition protocol for treatment of Crohn s disease A Pilot Trial
Prinicpal Investigator: Byron Vaughn
Currently Recruiting
Description: The purpose of this study is to evaluate the therapeutic feasibility of a Peptamen-based, oral nutrition dietary regimen for treatment of adult Crohn’s disease. Specifically we are evaluating if consuming 80-100% of caloric needs from Peptamen 1.5 for 4 weeks is feasible for the potential future use therapeutically in adult Crohn’s disease.
RCT01437: Proactive infliximab optimization using a pharmacokinetic dashboard versus standard of care in patients with Crohn s disease: The OPTIMIZE Trial
Prinicpal Investigator: Byron Vaughn
Currently Recruiting
Description: The purpose of this study is to find out if using a computer program (called iDose) to guide infliximab dosing is more effective and safer than using standard infliximab dosing over 52 weeks.
Fecal Microbiota Transplant for Postoperative Crohn's Disease
Prinicpal Investigator: Byron Vaughn
Currently Recruiting
Description: People with Crohn's disease often need surgery. The gut bacteria of people with Crohn's is associated with Crohn's disease coming back after surgery. Fecal microbiota transplant (FMT) after surgery might be a way to prevent Crohn's disease from coming back after surgery. This study aims to determine if fecal microbiota transplant (FMT) taken by capsules results in the same amount of good bacteria in the guts as FMT by colonoscopy in people with Crohn's disease who have had surgery.
Low sulfur fecal transplant for ulcerative colitis
Prinicpal Investigator: Byron Vaughn
Currently Recruiting
Description: This study is a pilot randomized controlled clinical trial examining how fecal microbiota transplant (FMT) given by capsules can change the bacteria and inflammation in people with active ulcerative colitis (UC). We will look at global changes of bacterial composition while on FMT versus those not on FMT.
Corrona Inflammatory Bowel Disease (IBD) Registry
Prinicpal Investigator: Byron Vaughn
Currently Recruiting
Description: This is a prospective, non-interventional, research study for patients with IBD under the care of a certified gastroenterologist. The primary objective for this registry is to prospectively study the natural history of IBD, the prevalence and incidence of comorbidities, targeted adverse events, and more, via questionnaires.
Microbiota Therapeutics Program
The Microbiota Therapeutics Program is active in actively recruiting patients for clinical trials related to Leukemia, Ulcerative Colitis, and more. Go to the UMN Microbiota Therapeutics Program website for more information.
Hepatology
Evaluation of the Safety and Efficacy of DUR-928 for Alcohol Relative Hepatitis - AHFIRM
Principal Investigator: Julie Thompson
Currently Recruiting
Description: A multicenter study evaluating the safety and impact of DUR-928 on outcomes for adult patients with alcohol related hepatitis.
Learn more about this study at study at ClinicalTrials.gov
ALTA TIPS: A 5-year Longitudinal Observational Study of Patients Undergoing TIPS Placement
Prinicpal Investigator: Nicholas Lim
Currently Recruiting
Description: ALTA is a multicenter consortium focused on the management of portal hypertension. ALTA TIPS is a longitudinal observational study of patients who are undergoing transjugular intrahepatic portosystemic shunt (TIPS) placement.
StudyFinder is a University of Minnesota website that displays a searchable listing of studies, which are extracted from ClinicalTrials.gov. At StudyFinder you can explore University health studies currently seeking participants.
Clinicaltrials.gov is a database of privately and publicly funded clinical studies conducted around the world.