Lung Biology T32 Training Program

Hand reaching for Binder

As faculty at a Carnegie Classification R1 University (very high research activity), we investigate fundamental lung science and patient-oriented problems.  In the last decade, our faculty have successfully competed for $68 million in sponsored grants. This includes 221 individual grants as well as an NHLBI T32 Training Grant in Lung Science that has supported 106 trainees over 23 years and is funded through 2024.

EDUCATIONAL PRINCIPLES & GOALS

Our program is based on the philosophy that successful development of a pulmonary scientist requires a well-designed, carefully crafted educational continuum from secondary school AP science courses to the award of a major research grant, or appointment as a research team leader in the private sector. These key tenets position this T32 to best meet each student’s needs and maximize the chance that each trainee can become a successful pulmonary scientist.

  • Enroll a diverse group of talented and motivated students to embark on training.

  • Maintain a training cohort with stable numbers in each level of training, providing an identifiable peer group for intellectual and social support.

  • Provide a broad range of well-defined pre-doctoral and post-doctoral level curricular pathways, matching expectations with opportunities.

  • Maintain a diverse multidisciplinary faculty blend of the very best University-wide physician-scientist and basic-scientist faculty to optimize intellectual vigor and provide proper role models for all trainees.

  • Combine the skills of MD and Ph.D. scientists from multiple disciplines in the program of each trainee.

  • Provide opportunities to interact with distinguished visiting faculty.

  • Use our large, land grant research university status to provide broad, interdisciplinary collaborative research and curricular activities in key new scientific areas related to lung science, such as bio-informatics, biomedical engineering, proteomics, metabolomics, and computational biology.

  • Educate Ph.D. scientists about pulmonary pathobiology and disease so that their research is more applicable to pathophysiology and therapy of disease and they are interested in long term careers in lung-related research.

  • Position trainees for success in team-based translational research by providing career development advising, professional skills and team science experience.

Three Major Curricular Areas

Cell & Molecular Biology

Cancer Biology & Control of Cell Growth
Peter Bitterman, MD
Colin Campbell, PhD
Stephen Hecht, PhD
Craig Henke, MD
Carol Lange, PhD*
Natalia Tretyakova, PhD

Regulation of Ion Transport 
Samuel Dudley, MD, PhD
David Ingbar, MD
Scott O’Grady, PhD

Cell Regulation by Hormones & Environment
David Bernlohr, PhD
Stephen Hecht, PhD
David Ingbar, MD
Carol Lange, PhD
Irina Stepanov, PhD

Applied Technologies & Experimental Therapeutics
Timothy Griffin, PhD
David Largaespada, PhD
Carston Wagner, PhD
Christine Wendt, MD

Immunobiology, Infection & Lung Inflammation
Anthony Baughn, PhD*
Bryce Binstadt, MD, PhD
Gary Dunny, PhD*
Mikael Elias, PhD*
Brian Fife, PhD
Kristin Hogquist, PhD*
Ryan Hunter, PhD*
Stephen Jamieson, PhD
Marc Jenkins, PhD
Ryan Langlois, PhD*
Louis Mansky, PhD
David Masopust, PhD
Daniel Mueller, MD
Angela Panoskaltsis-Mortari, PhD
P. Sriramarao Rao, PhD
Yoji Shimizu, PhD

*Faculty new to this application since the last competitive renewal
**Associate/Junior Mentors

Clinical & Public Health Research

COPD & Airways Disease
John Connett, PhD
Ken Kunisaki, MD
Christine Wendt, MD

Tobacco: Biologic Effects & Control
Steve Fu, MD, MSCE 
Dorothy Hatsukami, MD
Stephen Hecht, PhD
Anne Joseph, MD
Lisa Peterson, PhD*
Irina Stepanov, PhD*

Critical Care & Outcomes
Timothy Beebe, PhD
Mary Butler, PhD, MBA*
Timothy Church, PhD*
R. Adams Dudley, MD, MBA
Kristine Ensrud, MD
Marshall Hertz, MD
Karen Kuntz, ScD
Erin Krebs, MD, MPH*
Pamela Lutsey, PhD, MPH
James Neaton, PhD
Orly Vardeny, PharmD*
Craig Weinert, MD, MPH
Rachel Widome, MD, MHS*
Timothy Wilt, MD, MPH, MACP*

Public Policy, Environmental Health & Health Services
Bruce Alexander, PhD
Lynn Blewett, PhD
R. Adams Dudley, MD, MBA
Karen Kuntz, DSc
Jeffry Mandel, MD, PhD
Michael Osterholm, PhD, MPH

*Faculty new to this application since the last competitive renewal
**Associate/Junior Mentors

Systems Biology, Bioengineering & Bioinformatics

Systems Biology, Bioengineering & Regenerative Medicine
Victor Barocas, PhD
Filippo Colletti, PhD*
Arthur Erdman, PhD
Craig Henke, MD
Rolf Hubmayr, MD
John Marini, MD
Joseph Metzger, PhD
Brenda Ogle, PhD
John Osborn, PhD
Angela Panoskaltsis-Mortari, PhD

Bioinformatics & Biostatistics
Constantin Aliferis, MD, PhD
John Connett, PhD
Dan Knights, PhD*
Vipin Kumar, PhD
Eric Lock, PhD*
Cavan Reilly, PhD
Gyorgy Simon, PhD*

Neuroscience & Sleep
Timothy Ebner, MD, PhD
Conrad Iber, MD
Rachel Widome, MD, MHS

*Faculty new to this application since the last competitive renewal
**Associate/Junior Mentors

Training Faculty are drawn from four Academic Health Center colleges and the College of Science & Engineering. Faculty expertise extends across a broad spectrum, including pulmonary fibrosis; lung injury; lung cancer; COPD; sleep medicine; asthma; cystic fibrosis; and bioethics. Comprehensive resources and stable research funding in each area provide an outstanding training environment.