Nephrology Research

Nephrotic Syndrome Study Network Under the Rare Diseases Clinical Research Network (NEPTUNE)

Principal Investigator
Patrick Nachman, MD

Co-Investigators
Angie Lobo, MD
Sahar Koubar, MBBS
Anne Kouri, MD, MS
Michelle Rheault, MD

Study Coordinators
Brady Wallner

CLINICAL TRIAL

A Randomized, Double-blind, Placebo-controlled Phase 4 Clinical Trial to Evaluate the Long-term Safety and Efficacy of Avacopan in Participants With Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis

Principal Investigator
Sahar Koubar, MBBS

Co-Investigators
Nattawat Klomjit, MD 
Patrick Nachman, MD

Study Coordinators: 
Brady Wallner

CLINICAL TRIAL

Phase 3 Trial

A Phase 3 open- label, controlled, randomised, multi-centre trial comparing imlifidase and standard-of-care with standard-of-care alone in the treatment of severe anti-GBM antibody disease (Goodpasture disease)

Principal Investigator
Patrick Nachman, MD

Co-Investigators
Andrew Johnson, MD
Nattawat Klomjit, MD
Sahar Koubar, MBBS
Aahd Kubbara, MD
Katie Pendleton, MD
Sami Safadi, MD

Study Coordinator
Nicolas Rauwolf | [email protected]

CLINICAL TRIAL

A Multicenter, Single-arm, Open Label Trial to Evaluate Efficacy and Safety of Oral, Twice Daily LNP023 in Adult aHUS Patients Who Are Naive to Complement Inhibitor Therapy

Principal Investigator
Nattawat Klomjit, MD

Co-Investigators
Marshall Mazepa, MD

Study Coordinators
Brady Wallner

CLINICAL TRIAL

Kidney Precision Medicine Project (KPMP)

Principal Investigators 
Patrick Nachman, MD
Luiza Caramori, MD

Co-Investigators
Yanli Ding, MD, PhD
Paul Drawz, MD, MHS, MS
Siobhan Flanagan, MD
Tasma Harindhanavudhi, MD, MS
Beth Rogers, MD, MAS
Sami Safadi, MD
Sandeep Sharma, MD, FRCPC
Susan Wolf, JD

Study Coordinators 
Alison Alvear, PA-C, MPAS
Tosin Oluwole, MD, MPH, CCRP
Michelle Snyder, RN

Email: [email protected]

CLINICAL TRIAL

Systolic Blood Pressure Intervention Trial (SPRINT)

Blood Pressure and Kidney Function - SPRINT vs Electronic Health Record Data

Principal Investigator
Paul Drawz, MD

Program Manager
Nayanjot Kaur Rai, MPH, BDS

Kidney Precision Medicine Project (KPMP)

Co-Principal Investigators
Patrick Nachman, MD
Luiza Caramori, MD

Co-Investigators
Yanli Ding, MD, PhD
Paul Drawz, MD, MHS, MS
Siobhan Flanagan, MD
Tasma Harindhanavudhi, MD, MS
Beth Rogers, MD, MAS
Sami Safadi, MD
Sandeep Sharma, MD, FRCPC
Susan Wolf, JD

Study Coordinators 
Alison Alvear, PA-C, MPAS
Tosin Oluwole, MD, MPH, CCRP
Michelle Snyder, RN

Email: [email protected]

CLINICAL TRIAL

The Nephrotic Syndrome Study Network (NEPTUNE)

Principal Investigator
Patrick Nachman, MD

Co-Principal Investigators
Angie Lobo, MD
Sahar Koubar, MBBS
Anne Kouri, MD, MS
Michelle Rheault, MD

Study Coordinators 
Brady Wallner

CLINICAL TRIAL

A Study of the Efficacy and Safety of DMX-200 in Patients With FSGS Who Are Receiving an ARB (ACTION3)

Study Coordinator
Ariel Langenberger

CLINICAL TRIAL

A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Ravulizumab in Adult Participants With Immunoglobulin A Nephropathy (IgAN)

Principal Investigator
Sahar Koubar, MBBS

Co-Investigators
Nattawat Klomjit, MD 
Patrick Nachman, MD

Study Coordinators
Brady Wallner

CLINICAL TRIAL

A Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Study to Evaluate the Efficacy and Safety of Iptacopan (LNP023) in Idiopathic Immune Complex Mediated Membranoproliferative Glomerulonephritis (IC-MPGN)

Principal Investigator
Nattawat Klomjit, MD 

Co-Investigators
Sahar Koubar, MBBS

Study Coordinator:
Brady Wallner

CLINICAL TRIAL

Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy (REBOOT)

Principal Investigator
Patrick Nachman, MD

Co-Investigators
Katti Woerner, MD

Study Coordinators
Brady Wallner

CLINICAL TRIAL

Nephrotic Syndrome Study Network Under the Rare Diseases Clinical Research Network (NEPTUNE)

Principal Investigator
Patrick Nachman, MD

Co-Investigators
Angie Lobo, MD
Sahar Koubar, MBBS
Anne Kouri, MD, MS
Michelle Rheault, MD

Study Coordinators
Brady Wallner

CLINICAL TRIAL

The Nephrotic Syndrome Study Network (NEPTUNE)

Principal Investigator
Patrick Nachman, MD

Co-Principal Investigator
Angie Lobo, MD
Sahar Koubar, MBBS
Anne Kouri, MD, MS
Michelle Rheault, MD

Study Coordinators
Brady Wallner

CLINICAL TRIAL

A Phase 1 Study of FT819 in Participants With Moderate to Severe Active Systemic Lupus Erythematosus

Principal Investigator
Parastoo Fazeli, MD

Co-Investigators
Marta Michalska Smith, MD
Jerry Molitor, MD, PhD
Patrick H. Nachman, MD

Study Coordinator
Michelle Snyder, RN

CLINICAL TRIAL

A Phase 1/2, Open-label Study to Evaluate the Safety and Efficacy of Autologous CD19-specific Chimeric Antigen Receptor T Cells (CABA-201) in Subjects With Active Systemic Lupus Erythematosus

Principal Investigator
Patrick H. Nachman, MD

Co-Investigators
Parastoo Fazeli, MD
Marie Hu, MD
Nattawat Klomjit, MD 

Study Coordinator:
Tosin Oluwole, MD, MPH, CCRP
Victoria Quinones, RN

CLINICAL TRIAL

Kidney Precision Medicine Project (KPMP)

Co-Principal Investigators: 
Patrick Nachman, MD
Luiza Caramori, MD

Co-Investigators:
Yanli Ding, MD, PhD
Paul Drawz, MD, MHS, MS
Siobhan Flanagan, MD
Tasma Harindhanavudhi, MD, MS
Beth Rogers, MD, MAS
Sami Safadi, MD
Susan Wolf, JD

Study Coordinators: 
Alison Alvear, PA-C, MPAS
Tosin Oluwole, MD, MPH, CCRP
Michelle Snyder, RN

Email: [email protected]

CLINICAL TRIAL 

The Minnesota Glomerular Disease Program provides expert, individualized care to patients with any glomerular disease, with ongoing Phase 2 and Phase 3 clinical trials in Focal Segmental Glomerulosclerosis (FSGS) and IgA Nephropathy. 

Learn More

To provide patients with systemic inflammatory disease or vasculitis with cutting-edge, individualized, comprehensive and integrated multidisciplinary care and access to Phase 2 clinical trials in ANCA Vasculitis and Systemic Lupus Erythematosus. 

Learn More

Principal Investigator
Sabine Karam, MD

Co-Investigators
Nattawat Klomjit, MD
Sahar Koubar, MBBS
Patrick Nachman, MD

Study Coordinators
Krishna Allam
 

About Us
The Women Kidney Program (WKP) is a novel single-center registry for women with kidney disease.

Our Goal
The overall purpose is to help advance the field of nephrology through the rigorous study of women affected by different types of kidney disease, with the main objective to better understand and care for women with kidney disease.

What is different about women with kidney disease?
Kidney disease, such as chronic kidney disease is more prevalent in women compared to men, and women face higher prevalence of sex-specific issues such as menstrual disorders, infertility, sexual dysfunction, and earlier menopause. Enhancing knowledge and awareness about women's health topics is crucial in optimizing the care and overall health of women with kidney disease. 

Study Fact Sheet

Studies Involve:

• Looking at medical data
• Listening to and learning from patient's stories
• Tracking participants over time
• Carrying out surveys of different measures related to women's health

These methods help the research team collect detailed information about women with kidney disease and study risk factors to improve clinical outcomes.

Current and New Patients:

Thank you for participating in the WKP research at University of Minnesota. If your contact information changes, such as you move, please call or email ([email protected]) the study coordinator with your new contact information so we can stay in touch. 

Study Team
Sabrina Burn, MD
Parastoo Fazeli, MD
Sahar Koubar, MBBS
Angie S. Lobo, MD
Patrick Nachman, MD
Sisi Ma, PhD

Building Interdisciplinary Research Careers in Women’s Health (BIRCWH)

• About BIRCWH
• About BIRCWH at the University of Minnesota