RESEARCH

CLINICAL / EPIDEMIOLOGICAL RESEARCH

Blood Pressure

Systolic Blood Pressure Intervention Trial (SPRINT)
Blood Pressure and Kidney Function - SPRINT vs Electronic Health Record Data 

Principal Investigator
Paul Drawz, MD

Program Manager
Nayanjot Kaur Rai, MPH, BDS
rai00041@umn.edu

Diabetic Kidney Disease

Phase 2a Trial

A Phase 2a Multiple Ascending, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

Principal Investigator 
Patrick Nachman, MD

Co-Investigators
Surabhi Thakar, MD
Katti Woerner, MD

Study Coordinator
Mary McDonald, RN, CCRP
mcdo0664@umn.edu 

CLINICAL TRIAL

Transplantation Research (Kidney and Pancreas)

APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)

Principal Investigator
Rasha El-Rifai, MD

Co-Investigator
Richard Spong, MD

Study Coordinator
Ghislaine Feussom, MPH
feuss001@umn.edu

CLINICAL TRIAL 


Phase 3

A Randomized, Controlled, Multi-Center, Safety and Efficacy Study of FCR001 Cell-Based Therapy Relative to a Tacrolimus and Mycophenolate-Based Regimen in de Novo Living Donor Renal Transplant Recipients, and Safety in FCR001 Donors (FREEDOM-1)

Principal Investigator
Erik Finger, MD, PhD

Co-Investigator
Rasha El-Rifai, MD

Study Coordinator
Marcia Brott
brott001@umn.edu

CLINICAL TRIAL 


Immunosuppression Reduction in Failed Allograft Guided by cfDNA

Principal Investigator
Adam Bregman, MD, MBA

Study Coordinator
Ghislaine Feussom, MPH
feuss001@umn.edu

CLINICAL TRIAL


Cf-DNA Assay During Treatment of Acute Rejection-Pilot Study

Principal Investigator
Arthur Matas, MD

Co-Investigators
Adam Bregman, MD, MBA

Study Coordinators
Marcia Brott
brott001@umn.edu

Alyssa Nelson, BS
nels9147@umn.edu

CLINICAL TRIAL

Glomerular Diseases & Vasculitis Research

Anti-GBM

Phase 3 Trial

A Phase 3 open- label, controlled, randomised, multi-centre trial comparing imlifidase and standard-of-care with standard-of-care alone in the treatment of severe anti-GBM antibody disease (Goodpasture disease)

Principal Investigator
Patrick Nachman, MD

Co-Investigators
Nattawat Klomjit, MD
Sahar Koubar, MBBS
Katie Pendleton, MD
Sami Safadi, MD

Study Coordinator
Joy Bolea, RN, MS
jbolea@umn.edu

Mary McDonald, RN, CCRP
mcdo0664@umn.edu

FOCAL SEGMENTAL GLOMERULOSCLEROSIS (FSGS)

Phase 2a Trial

A Phase 2a Multiple Ascending, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

Principal Investigator
Patrick Nachman, MD

Co-Investigators
Surabhi Thakar, MD
Katti Woerner, MD

Study Coordinator
Mary McDonald, RN, CCRP
mcdo0664@umn.edu

CLINICAL TRIAL

IGA NEPHROPATHY

Phase 3 Trial
A Randomized, Double-blind, Placebo-controlled, Phase 3 Study of the Safety and Efficacy of OMS721 in Patients with Immunoglobulin A (IgA) Nephropathy (ARTEMIS - IGAN)

Principal Investigator
Patrick H. Nachman, MD

Co-Investigators
Surabhi Thakar, MD

Study Coordinators
Mary McDonald, RN, CCRP
mcdo0664@umn.edu

Joy Bolea, RN, MS
jbolea@umn.edu

CLINICAL TRIAL


A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Subjects With Immunoglobulin A Nephropathy

Principal Investigator
Sahar Koubar, MBBS

Co-Investigators
Nattawat Klomjit, MD
Patrick H. Nachman, MD

Study Coordinators
Joy Bolea, RN, MS
jbolea@umn.edu

CLINICAL TRIAL

MEMBRANOUS NEPHROPATHY

Phase 2 Trial

Efficacy of Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy (REBOOT)

Principal Investigator
Patrick Nachman, MD

Co-Investigator
Surabhi Thakar, MD
Katti Woerner, MD

Study Coordinators
Joy Bolea, RN, MS
jbolea@umn.edu

Mary McDonald, RN, CCRP
mcdo0664@umn.edu

CLINICAL TRIAL

NEPHROTIC SYNDROME

The Nephrotic Syndrome Study Network (NEPTUNE)

Principal Investigator
Patrick Nachman, MD

Co-Principal Investigator
Michelle Rheault, MD

Study Coordinators
Joy Bolea, RN, MS
jbolea@umn.edu

Mary McDonald, RN, CCRP
mcdo0664@umn.edu

CLINICAL TRIAL


Phase 2a Trial

A Phase 2a Multiple Ascending, Placebo-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of GFB-887, a TRPC5 Channel Inhibitor, in Patients With Diabetic Nephropathy, Focal Segmental Glomerulosclerosis, and Treatment-Resistant Minimal Change Disease

Principal Investigator
Patrick Nachman, MD

Co-Investigators
Surabhi Thakar, MD
Katti Woerner, MD

Study Coordinator
Mary McDonald, RN, CCRP
mcdo0664@umn.edu

CLINICAL TRIAL

SYSTEMIC LUPUS ERYTHEMATOSUS (SLE)

Phase 3 Trial

A Phase III, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study To Evaluate The Efficacy And Safety Of Obinutuzumab In Patients With ISN/RPS 2003 Class III Or IV Lupus Nephritis (REGENCY)

Principal Investigator
Surabhi Thakar, MD

Co-Investigators
Patrick Nachman, MD
Katti Woerner, MD

Study Coordinator
Joy Bolea, RN, MS
jbolea@umn.edu

Mary McDonald, RN, CCRP
mcdo0664@umn.edu

CLINICAL TRIAL


A Phase 2a Randomized Placebo-Controlled Double-Blind Multicenter Trial of VIB4920 for Active Lupus Nephritis (ITN091AI)

Principal Investigator
Patrick H. Nachman, MD

Study Coordinators
Mary McDonald, RN, CCRP
mcdo0664@umn.edu

Joy Bolea, RN, MS
jbolea@umn.edu

CLINICAL TRIAL

Programs

MINNESOTA GLOMERULAR DISEASE PROGRAM

To provide patients with systemic inflammatory disease or vasculitis with cutting-edge, individualized, comprehensive and integrated multidisciplinary care and access to clinical trials. Learn More

MINNESOTA MULTIDISCIPLINARY VASCULITIS PROGRAM

To provide patients with glomerular disease with expert, individualized care and access to clinical trials. Learn More

StudyFinder is a University of Minnesota website that displays a searchable listing of studies, which are extracted from ClinicalTrials.gov. At StudyFinder you can explore University health studies currently seeking participants.

Clinicaltrials.gov is a database of privately and publicly funded clinical studies conducted around the world.