Guru Trikudanathan

Associate Professor of Medicine, Division of Gastroenterology, Hepatology and Nutrition
Section Lead, Advanced Endoscopy


Administrator Info
Name: GI Division
Phone: 612-625-8999
Mail: 420 Delaware Street SE, MMC 36, Minneapolis, MN 55455

My overarching research interests lie in strategies towards the optimal management of acute pancreatitis and its complications, the most common cause for hospitalization among gastrointestinal diseases. My other main focus has been on exploring modalities for early diagnosis of chronic pancreatitis, a debilitating condition that pose a major detriment to the quality of life of these patients. Other keen interests include pancreatic endo-therapy through endoscopic ultrasound and endoscopic retrograde cholangio-pancreatography for management of complex pancreatic and biliary conditions. I have nearly 50 peer reviewed publications and serve at the American Society of Gastrointestinal Endoscopy' sTechnology committee.

Research Summary

  • Management of necrotizing pancreatitis
  • Early diagnosis of chronic pancreatitis
  • Pancreatic Endotherapy
  • Diagnostic and interventional EUS

Teaching Summary

Pancreatology; Therapeutic Endoscopy, Interventional endoscopic ultrasound

Clinical Summary

Endoscopic and multidisciplinary management of complex pancreatic and biliary diseases; Acute and recurrent pancreatitis; Chronic pancreatitis; Necrotizing Pancreatitis; Pancreatic and biliary cancer; Benign bile duct strictures and injuries


MBBS, Madurai Medical College

Fellowships, Residencies, and Visiting Engagements

University of Minnesota
Internal Medicine, Residency
University of Connecticut Health Center
Therapeutic Endoscopy,
University of Minnesota

Honors and Recognition

National Pancreas Foundation Award
Fellowship Leadership Award
Dr. Vadamalayan Endowment award
Association of Surgeons of India medal
Dr. M. Srinivasan Medal for best clinical research paper
Young Investigator Award, American Pancreas Association (2013-2015)
Top Doctor: Rising Star, Mpls St. Paul Magazine (2018, 2019)

Professional Memberships

American Gastroenterology Association
American Society of Gastrointestinal Endoscopy
American College of Gastroenterology
American Pancreas Association
Selected Publications

Selected Publications

Trikudanathan G, Vege SS. Current concepts of the role of abdominal compartment syndrome in acute pancreatitis - an opportunity or merely an epiphenomenon. Pancreatology. 2014 Jul-Aug; 14(4): 238-43,
Trikudanathan G, Shaukat A, Bakman Y. Proliferating pilar tumor of scalp metastasizing to pancreas- Diagnosis with Endoscopic Ultrasound guided Fine Needle Aspiration (EUS-FNA). Clin Gastroenterol Hepatol 2015 Nov; 13(11): e164-5,
Trikudanathan G, Freeman ML Electrohydraulic lithotripsy of large pancreatic duct stones by using digital pancreatoscopy. Gastrointest Endosc. Jun;83(6):1285-,
Trikudanathan G, Walker S, Munigala S et al. Diagnostic performance of contrast enhanced MRI with secretin- stimulated MRCP (sMRCP) for non- calcific chronic pancreatitis (NCCP) - a comparison with histopathology. Am J Gastroenterol Nov; 110(11): 1598-606. ,
Trikudanathan G, Vega-Peralta J, Malli A et al. Diagnostic performance of endoscopic ultrasound (EUS) for non-calcific chronic pancreatitis based on histopathology. Am J Gastroenterol. 2016 Apr;111(4):568-74 ,