Assistant Professor of Medicine, Cardiovascular Division
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Biography
Summary Study the effect of mitochondrial calcium handling on heart failure arrhythmia.
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Education
Graduate School
PhD, Fourth Military Medical University
MS, Fourth Military Medical University
Additional Details
PhD, Fourth Military Medical University
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Publications
Selected Publications
Xie A, Kang GJ, Kim EJ, Feng F, Givens SE, Ogle BM, Dudley SC Jr. Lysosomal Ca2+ flux modulates automaticity in ventricular cardiomyocytes and correlates with arrhythmic risk. PNAS Nexus. 2023 May 25;2(6):pgad174.
An Xie, Gyeoung-Jin Kang, Eun Ji Kim, Hong Liu, Feng Feng, Samuel C. Dudley. c-Src is responsible for mitochondria-mediated arrhythmic risk in ischemic cardiomyopathy. Circ Arrhythm Electrophysiol. 2024 Aug 30:e013054. doi: 10.1161/CIRCEP.124.013054..
Xie A, Zhou A, Liu H, Shi G, Liu M, Boheler KR, Dudley SC Jr. Mitochondrial Ca2+ flux modulates spontaneous electrical activity in ventricular cardiomyocytes. PLoS One. 2018 Jul 12; 13(7):e0200448.
Xie A, Song Z, Liu H, Zhou A, Shi G, Wang Q, Gu L, Liu M, Xie LH, Qu Z, Dudley SC Jr. Mitochondrial Ca2+ Influx Contributes to Arrhythmic Risk in Nonischemic Cardiomyopathy. J Am Heart Assoc. 2018 Apr 7;7(8)
An Xie, Hong Liu, Gyeoung-Jin Kang, Feng Feng, Samuel C Dudley Jr. Reduced sarcoplasmic reticulum Ca2+ pump activity is antiarrhythmic in ischemic cardiomyopathy. Heart Rhythm. 2022 Dec;19(12):2107-2114.
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Research
The relationship between mitochondrial calcium handling and heart failure arrhythmia.
