Susan Kline, MD, MPH

Professor of Medicine, Division of Infectious Diseases and International Medicine

Susan Kline

Contact Info

Mailing Address:
420 Delaware ST SE
Room D416
MMC 250
Minneapolis, MN 55455

Administrative Assistant Name
IDIM Admin

Administrative Phone

Administrative Email

Administrative Fax Number

Professor of Medicine, Division of Infectious Diseases and International Medicine

General ID, HIV, Tuberculosis

Medical School, University of Minnesota, Minneapolis, MN

Residency, University of Minnesota, Minneapolis, MN

Fellowship, University of Minnesota, Minneapolis, MN

Bachelor's Degree, University of Colorado, Boulder, CO


After graduating from the University of Minnesota Medical School in 1988, Dr. Kline completed her Internal Medicine residency at the University of Minnesota Medical Center and its affiliated sites. Following completion of her residency she worked in General Internal Medicine and Emergency Medicine for one year at the University of Minnesota Medical Center. She then began her Infectious Disease Fellowship at the University of Minnesota Medical Center and affiliated sites. She also completed her Masters in Public Health during her ID fellowship with an emphasis in Infectious Disease Epidemiology. Dr. Kline then for joined the Internal Medicine faculty in 1994 and is currently a Professor. In addition she has been the Medical Director for Infection Control at the University of Minnesota Medical Center since 1996. She helped establish the Antibiotic Management Team at the University of Minnesota Medical Center in 2007. She currently is the Co-Director of the General Infectious Disease service and the Physician Director of Antimicrobial Management for the ID Division. She also is Co-Director of the HIV Family Clinic in the Delaware Street Clinic. She is the Hospital Epidemiologists for the University of Minnesota Medical Center.

Awards & Recognition

  • Best Doctors in America® (2011-2012)
  • Recipient of Department of Medicine Clinical Excellence Award (September, 2009)
  • Alpha Omega Alpha Medical Society–University of Minnesota Medical School (1987)
  • Delta Omega Honorary Public Health Society 1995
  • Faculty Clinical Excellence Award, Department of Medicine, University of Minnesota (2004, 2009)

Professional Associations

  • Medical Director of Infection Control, University of Minnesota Health
  • Fellow, Society of Hospital Epidemiologists of America (2010)
  • Member, Infectious Disease Society of America (IDSA) (1994-present)


Research Summary/Interests

Her research interests include the epidemiology of healthcare associated infections and prevention of these infections. In addition to her work on Infection Control and Antibiotic Decision Support systems Susan Kline is currently conducting a randomized clinical trial, “Effectiveness of Screening and Decolonization of S. aureus in Surgery Outpatients”. She recently completed another RCT in 2013, “A Trial for the Safety and Effectiveness of a Novel Antimicrobial-Coated Foley Catheter for Reduction of CAUTI”.


  • Kline S, Neaton J, Lynfield R, Ferrieri P, Kulasingam S, Dittes K, Glennen A, Jawahir S, Kaizer A, Menk J, and Johnson J. Randomized controlled trial of a self-administered 5-day antiseptic bundle versus usual disinfectant soap showers for pre-operative eradication of Staphylococcus aureus colonization. Accepted June 5, 2018 for publication in Infect Control Hosp Epidemiol.
  • Sabin AP, Ferrieri P, Kline S. Mycobacterium abscessus Complex Infections in Children: A Review. Curr Infect Dis Rep. 2017 Oct;19(11):46. PMID: 28983867 doi: 10.1007/s11908-017-0597-2
  • Guspiel A, Menk J, Streifel A, Messinger K, Wagner J, Ferrieri P, Kline S. Management of Risks From Water and Ice From Ice Machines for the Very Immunocompromised Host: A Process Improvement Project Prompted by an Outbreak of Rapidly Growing Mycobacteria on a Pediatric Hematopoietic Stem Cell Transplant (Hsct) Unit. Infect Control Hosp Epidemiol 2017;38:792-800.doi:
  • DeVries A, Talley P, Sweet K, Kline S, Stinchfield P, Tosh P, et al. (2016) Development and Implementation of the Ebola Traveler Monitoring Program and Clinical Outcomes of Monitored Travelers during October – May 2015, Minnesota. PLoS ONE 11(12): e0166797. doi:10.1371/journal.pone.0166797
  • England, D, Houseman, J, Horn, L, Mascotti, K, Kline, S. Documented Transmission of Extended-Spectrum Beta-Lactamase–Producing Klebsiella pneumoniae From Patient to Gastroscope. Infect Control Hosp Epidemiol. 2016 Apr;37(4):493-4. doi: 10.1017/ice.2015.337. Epub 2016 Jan 14. PMID: 26763189 [PubMed - in process]
  • Drawz S, Porter S, Kuskowski M, Johnston B, Clabots C, Kline S, Ferrieria P, Johnson J. Variation in resistance traits, phylogenetic background, and virulence genotypes among Escherichia coli clinical isolates from adjacent hospital campuses serving distinct patient populations. Antimicrob Agents Chemother. 2015 Sep;59(9):5331-9. PMID: 26100703
  • Iroh Tam PY, Kline S, Ward G, Ferrieri P. Nontuberculous mycobacterial infection in children: a case series. Epidemiol Infect. 2015 Nov;143(15):3173-81. PMID: 25762105
  • Leuck AM, Johnson J, Hunt M, Dhody K, Kazempour K, Ferrieri P, Kline S. Safety and Efficacy of a Novel Silver-Impregnated Catheter-Associated Urinary Catheter System for Preventing Bacteriuria: a Pilot Randomized Clinical Trial. Am J Infect Control. 2015 Mar 1;43(3):260-5. PMID: 25728152
  • Iroh Tam PY, Kline S, Wagner JE, Guspiel A, Streifel A, Ward G, Messinger K, Ferrieri P. Rapidly growing mycobacteria among pediatric hematopoietic cell transplant patients traced to the hospital water supply. Pediatr Infect Dis J. 2014 Oct;33(10):1043-6. PMID:24781138
  • Kline, S, Highness, M, Herwaldt, L, Perl, T. Variable Screening and Decolonization Practices for Staphylococcal aureus in pre-surgical patients. Infect Control Hosp Epidemiol. 2014 Jul;35(7):880-2. Epub 2014 May 20. PMID: 24915219


Academic Interests and Focus

Course Director HIV Clinic elective rotation for Internal Medicine residents; Bedside teaching of medical students, residents and fellows; Co-Director Emerging Infections CME course



  • Infectious Disease


Delaware Street Clinic (Infectious Disease/HIV Clinic)

Board Certifications

  • Infectious Diseases and Internal Medicine

Clinical Interests

Her clinical interests include general infectious diseases, TB, tropical infectious diseases and HIV/AIDs, including prevention of perinatal transmission of HIV. She sees patients in the Delaware Street Clinic and does ID consultations in the University of Minnesota Medical Center; Antibiotic Management Team