Administrative Contact
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Dr. Crane sparked his passion for basic and translational research at the University of Portland, where he received his BA in Psychology in 2008. Dr. Crane then received his MS PhD in Neuroscience from Central Michigan University in 2012 and 2014, respectively, focusing on stem cell-mediated repair and regeneration of the degenerating striatum in Huntington’s disease. In the lab of Dr. Walter Low, Dr. Crane completed an NIH-funded postdoctoral fellowship at the University of Minnesota with a focus on the genome engineering of stem cells toward cellular/regenerative therapies for various diseases and disorders. As a researcher within the labs of Dr. Branden Moriarity and Dr. Beau Webber, Dr. Crane developed platforms for genome engineering of induced pluripotent stem cells and differentiation towards macrophages, key immune cells in the innate and adaptive response to injury and disease. Dr. Crane joined the Division of Gastroenterology, Hepatology, and Nutrition in the Department of Medicine at the University of Minnesota in 2024 at the rank of Assistant Professor. Dr. Crane is currently investigating the role of macrophages in chronic inflammation and cancer and employing genome engineering strategies to enhance the function of iPSC-macrophages for cellular therapies.
Expertise: Stem cells and developmental biology, immunology, regenerative medicine, neuroscience
Induced pluripotent stem cells (iPSCs) have revolutionized the fields of developmental biology and regenerative medicine. The Crane Lab, in collaboration with University of Minnesota faculty, is leveraging iPSCs in the following ways:
Past Awards and Research Support:
Ongoing Research Support: