Casey Dorr, MS, PhD

Associate Professor, Division of Nephrology & Hypertension
Associate Professor, Division of Nephrology & Hypertension
Administrator Info
Phone: 612-624-9444
Fax: 612-626-3840
Email: [email protected]
Administrator Info
Phone: 612-624-9444
Fax: 612-626-3840
Email: [email protected]
Summary
Casey R. Dorr, PhD, was born and raised in Bemidji, Minnesota and is a first-generation Mille Lacs Band of Ojibwe descendent. He graduated with a Bachelor of Science in cell biology and chemistry from the University of Minnesota Duluth. He trained in molecular virology as an NIH funded trainee at the Italian National Agency for New Technologies, Energy and Sustainable Economic Development, ENEA-Casaccia Research Center, in Rome.
Dr. Dorr earned his Doctor of Philosophy in molecular, cellular, developmental biology and genetics from the University of Minnesota Twin Cities. His PhD thesis was titled “Compounds Derived from Birch Trees that Inhibit HIV-1 Replication.” Dr. Dorr completed post-doctoral training in cancer genetics at the University of Minnesota Masonic Cancer Center. Dr. Dorr completed further post-doctoral training in molecular epidemiology, pharmacogenomics of transplantation at Hennepin Healthcare Research Institute (HHRI).
Dr. Dorr won the James R. Gillette award from the American Society for Pharmacology and Experimental Therapeutics (ASPET) for best drug metabolism manuscript of 2017 titled: “CRISPR/Cas9 genetic modification of CYP3A5 *3 in HuH-7 human hepatocyte cell line leads to cell lines with increased midazolam and tacrolimus metabolism.” Dr. Dorr is a life member of the Society for the Advancement of Chicanos and Native Americans in Science (SACNAS), a Sequoyah Fellow of the American Indian Science and Engineering Society (AISES), and a member of the American Society of Transplantation (AST) and American Society of Nephrology (ASN). Dr. Dorr is Co-Director for the University of Minnesota’s Clinical and Translational Sciences Institute’s Pathways to Research Program (PReP) and Advanced Pathways to Research Program (A-PReP).
Dr. Dorr’s lab investigates genetic variants associated with drug metabolism in kidney transplant recipients through pharmacogenomics and functional analysis in bioengineered cell lines. The Dorr lab also investigates the molecular and cellular mechanisms of kidney allograft loss through association of biopsy spatialomics and long-term clinical outcomes data. Dr. Dorr’s research has special focus aimed to solve health disparities through translational research, precision medicine and training of the next generation of scientists.
Society for the Advancement of Chicanos and Native Americans in Science (SACNAS)
American Indian Science and Engineering Society (AISES)
American Society of Nephrology
American Society of Transplantation
Expertise
Pharmacogenomics
Molecular Genetics
Drug Metabolism
Spatialomics
Genomics
Transcriptomics
Cell line engineering
Clinical Outcomes