Joshua Rhein, MD

Assistant Professor of Medicine, Division of Infectious Diseases and International Medicine

Joshua Rhein

Contact Info

Mailing Address:
420 Delaware ST SE
D416 Mayo Memorial Building
MMC 250
Minneapolis, MN 55455

Administrative Assistant Name
IDIM Admin

Administrative Phone
612-624-9996

Administrative Email
IDIMDivision@umn.edu

Administrative Fax Number
612-625-4410

Assistant Professor of Medicine, Division of Infectious Diseases and International Medicine


Cryptococcal Meningitis, HIV/AIDS, Tropical Medicine


Medical School, University of Minnesota, Minneapolis, MN

Residency, Indiana University, Bloomington, IN

Fellowship, University of Minnesota, Minneapolis, MN

Summary

Dr. Rhein has a broad background in global health and infectious diseases, with specific focus on fungal infections and central nervous system infections in resource-limited areas. His primary expertise is on cryptococcal meningitis and other AIDS-related opportunistic infections, as well as HIV immune reconstitution inflammatory syndrome (IRIS). His current research is focused on improving the clinical outcomes of HIV-infected persons with cryptococcal meningitis, a globally neglected disease which is the second most common AIDS-defining opportunistic infection in Sub-Saharan Africa. Dr. Rhein has been an investigator on several large, guideline-informing clinical trials on HIV-associated meningitis. Current primary investigations are centered on determining the long-term effects of antiretroviral therapy on outcomes in cryptococcal meningitis. Dr. Rhein currently splits his time between the University of Minnesota and the Infectious Disease Institute in Kampala, Uganda. He has been actively engaged in research in Uganda since 2005 as a medical student. Providing on-the-ground leadership for both the study team and international trainees, Dr. Rhein enjoys and has a demonstrated commitment to mentoring Ugandan and American medical students, residents, and infectious disease fellows. As the Director of Training and Research for the University of Minnesota Health Sciences Uganda Hub since 2017, Dr. Rhein provides direct supervision and mentorship for UMN-affiliated trainees in Uganda. Dr. Rhein also serves as co-director of the new East African Clinical Tropical Medicine Course, a joint effort between the University of Minnesota, the Infectious Diseases Institute, and Makerere University

Expertise

  • Cryptococcal Meningitis
  • HIV/AIDS
  • Fungal Infections
  • Tropical Medicine

Awards & Recognition

  • Fogarty Global Health Fellowship (2015)
  • Young Investigator Award, IDWeek (2012-15)
  • Arnold P. Gold Foundation Humanism in Medicine Award (2006)
  • Walter H. Judd International Professional Research Fellowship (2005-06)
  • Wesley W. Spink Research Award (2005-06)

Research

Research Summary/Interests

  • Treatment of HIV-Associated Cryptococcal Meningitis
  • Diagnosis of CNS Infections
  • Management of Immune Reconstitution Inflammatory Syndrome

Teaching

Academic Interests and Focus

East African Clinical Tropical Medicine Course; Uganda Research Training Collaborative

Clinical

Clinical Interests

Meningitis; Invasive Fungal Infections; HIV/AIDS