Eugenia Shmidt

Associate Professor, Division of Gastroenterology, Hepatology and Nutrition
Founder/Director, IBD Preconception and Pregnancy Planning Clinic
Co-Director, IBD Program


Administrator Info
Name: GI Division
Phone: 612-625-8999
Fax: 612-625-5620
Mail: 420 Delaware St SE, MMC 36, Minneapolis, MN 55455

Dr. Shmidt received her bachelor's degree at Cornell University in Ithaca, NY and her medical degree from Mayo Clinic in Rochester, MN. She continued at Mayo Clinic where she completed residency in internal medicine. She then went on to complete a fellowship in gastroenterology at Mount Sinai Hospital in New York City.Dr. Shmidt specializes in inflammatory bowel disease with expertise in fertility, preconception and pregnancy care. She has published in multiple academic journals on various aspects of IBD, including sexual function.Dr. Shmidt serves as a member of the American Gastroenterology Association's national guideline committee for Drug Therapy for Crohn's disease. She also serves on the Women's Committee for the American College of Gastroenterology.At the University of Minnesota, Dr. Shmidt serves as the Co-Director of the IBD Program. She also co-leads the IBD Clinical Trials Program.In 2019, Dr. Shmidt was a recipient of the University of Minnesota's Biomedical Research Awards for Interdisciplinary New Science (BRAINS) to study the effect of the microbiome on fertility. Also, she is currently building a national registry to study the impact of pouch surgery on fertility in women with ulcerative colitis.At the University of Minnesota, Dr. Shmidt launched a multi-disciplinary clinic for women with IBD – the Inflammatory Bowel Disease Preconception and Pregnancy Planning (IPREPP) Clinic. The decision to become pregnant is difficult for women with IBD because of safety concerns related to the disease and the medications used for treatment. Oftentimes, women with IBD receive mixed messages from various specialists regarding pregnancy. The goal of the IPREPP clinic is to combine the expertise of IBD specialty care and maternal fetal medicine to offer comprehensive pre-conception and pregnancy counseling and care to women with IBD.In the IPREPP Clinic, women with IBD discuss pregnancy with two different specialists – Dr. Shmidt (an IBD specialist) and a maternal fetal medicine physician. The IPREPP Clinic is the only one of its kind in the Midwest and one of only a few in the world.

Research Summary

  • Pregnancy in inflammatory bowel disease
  • Impact of inflammatory bowel disease surgery on female fertility
  • Female and male sexual function in inflammatory bowel disease
  • Safety and effectiveness of various biologic and non-biologic therapies in the treatment of inflammatory bowel disease

Clinical Summary

Inflammatory bowel disease; female fertility and pregnancy; upper endoscopy; colonoscopy; chromoendoscopy


MD, Mayo Medical School

Fellowships, Residencies, and Visiting Engagements

Internal Medicine, Residency
Mayo Graduate School of Medicine
Gastroenterology, Fellowship
Icahn School of Medicine at Mount Sinai

Honors and Recognition

Recipient, Biomedical Research Award for Interdisciplinary New Science (2019-2020)
Top Doctor - Rising Star, Mpls.St.Paul Magazine (2019, 2020)
Selected Publications

Selected Publications

Shmidt E, Suárez-Fariñas M, Mallette M, Moniz H, Bright R, Shah SA, Merrick M, Shapiro J, Xu F, Sands B, Saha S. A Longitudinal Study of Sexual Function in Women With Newly Diagnosed Inflammatory Bowel Disease. Inflamm Bowel Dis. 2019 Jun 18;25(7):1262-1270,
Shmidt E, Kochhar G, Hartke J, Chilukuri P, Meserve J, Chaudrey K, Koliani-Pace JL, Hirten R, Faleck D, Barocas M, Luo M, Lasch K, Boland BS, Singh S, Vande Casteele N, Sagi SV, Fischer M, Chang S, Bohm M, Lukin D, Sultan K, Swaminath A, Hudesman D, Gupta N, Kane S, Loftus EV Jr, Sandborn WJ, Siegel CA, Sands BE, Colombel JF, Shen B, Dulai PS. Predictors and Management of Loss of Response to Vedolizumab in Inflammatory Bowel Disease. Inflamm Bowel Dis. 2018 Oct 12;24(11):2461-2467,
Shmidt E, Suárez-Fariñas M, Mallette M, Moniz H, Bright R, Shah SA, Merrick M, Shapiro J, Xu F, Saha S, Sands BE. Erectile Dysfunction Is Highly Prevalent in Men With Newly Diagnosed Inflammatory Bowel Disease.Inflamm Bowel Dis. 2019 Jul 17;25(8):1408-1416,