Chen, X., Gu, J., Neuwald, A.F., Hilakivi-Clarke, L.A., Clarke, R. & Xuan, J. “Identifying intracellular signaling modules and exploring pathways associated with breast cancer recurrence.” Sci Rep 11: 385. doi: 10.1038/s41598-020-79603-5, 2021.
Fan, M., Xia, P., Clarke, R., Wang, Y. & Li, L. “Radiogenomic signatures reveal multiscale intratumour heterogeneity associated with biological functions and survival in breast cancer.” Nature Commun, 11:4861 doi 10.1038/s41467-020-18703-2, 2020.
Remoli, A.L., Sgarbanti, M., Perrotti, E., Acchioni, M., Orsatti, R., Acchioni, B., Clarke, R. & Marsili, G. “IĸB kinase-ε-mediated phosphorylation triggers IRF-1 degradation in breast cancer cells.” Neoplasia, 22: 459-469, 2020
Sengupta, S. Sevigny, C., Jordan, V.C. & Clarke, R. “Estrogen induced apoptosis in breast cancers is phenocopied by blocking de-phosphorylation of eIF2-alpha protein.” Mol Cancer Res, 17: 918-928, 2019.
Hilakivi-Clarke, L.A., Wärri, A., Bouker, K.B., Zhang, X., Cook, K.L., Jin, L., Zwart, A., Nguyen, N., Hu, R., Cruz, I.M., de Assis, S., Wang, X., Xuan, J., Wang, Y., Wehrenberg, B. & Clarke R. “In utero exposure to ethinyl estradiol predisposes to tamoxifen resistance and breast cancer recurrence in a preclinical model.” J Natl Cancer Inst, doi: 10.1093/jnci/djw188, 2017.
Cook, K.L., Soto-Pantoja, D.R., Clarke, P.A.G., Cruz, I., Zwart, A., Wärri, A., Roberts, D.D., & Clarke, R. “Endoplasmic reticulum stress protein, GRP78, modulates lipid metabolism to control breast tumor drug sensitivity and activate anti-tumor immunity.” Cancer Res, 76:5657-5670, 2016.
Hu, R., Wärri, A., Jin, L., Zwart, A., Riggins, R.B. & Clarke, R. “NFκB signaling is required for XBP1 (U and S) mediated effects on antiestrogen responsiveness and cell fate decisions in breast cancer cells.” Mol Cell Biol, 35: 379-390, 2015.
