Leadership


Minneapolis, MN 55455
Bio
Jakub Tolar, MD, PhD is the Dean of the University of Minnesota Medical School and a Distinguished McKnight Professor in the Department of Pediatrics, Blood and Marrow Transplant & Cellular Therapy. He is also the Vice President for Clinical Affairs at the University of Minnesota, Board Chair for University of Minnesota Physicians and co-leader of M Health Fairview, the Joint Clinical Enterprise between the University of Minnesota Medical School, University of Minnesota Physicians and Fairview Health Services. An internationally recognized physician and researcher, Dr. Tolar is known for his care of patients with recessive dystrophic epidermolysis bullosa. His research is focused on using hematopoietic stem cell transplant as a treatment for rare genetic disorders. Originally from the Czech Republic, Dr. Tolar received his medical education (MD) in Prague at Charles University. In 1992, he came to the University of Minnesota, where he completed his PhD in Molecular, Cellular & Developmental Biology and Genetics.
Research Summary
Dr. Tolar's research focuses on finding new ways of treating children with lethal diseases - cancer, inborn errors of metabolism, and devastating genetic disorders - using stem cell transplantation. He is also looking for safer and more effective methods of repairing and using a patient's own cells in diseases such as epidermolysis bullosa, mucopolysaccharidosis type I (Hurler syndrome), Fanconi anemia, and dyskeratosis congenita. Additional research interests include: reducing the negative effects of stem cell transplantation (such as using mesenchymal stromal cells for graft-versus-host disease), creation and use of induced pluripotent stem cells, gene therapy using gene addition (with viral vectors and trasposons), or gene editing (with synthetic nucleases to repair genes).
Clinical Summary
Blood and marrow transplantation; Gene therapy for correction of genetic diseases
Education
Fellowships, Residencies, and Visiting Engagements
Licensures and Certifications
Honors and Recognition
Professional Memberships
Languages
Selected Presentations
Grants and Patents
Patents

Bio
Administrator Info
Name: Craig Olson
Phone: 612-626-6577
Email: olso7966@umn.edu
Mail: 420 Delaware ST SE
MMC 250
Campus Delivery Code 8250A
Minneapolis, MN 55455
Summary
Timothy Schacker, M.D. is a professor of Medicine and Director of the Program in HIV Medicine at the University of Minnesota. He joined the faculty in 1996. Dr. Schacker received his M.D. from the University of Minnesota in 1986 and completed a residency in Internal Medicine at the Oregon Health Sciences University and Infectious Disease Fellowship at the University of Washington in 1993. He then joined the faculty of the University of Minnesota.Dr. Schacker is interested in how HIV causes immune suppression and why antiretrovirals do not fully restore immunity. His group focuses on inflammatory damage in lymphatic tissues; the principal site of HIV infection, that results in fibrosis of the lymphatic structures required to maintain a normal population of CD4 cells. They are testing novel therapies to prevent and/or reverse this process and slow T cell depletion in HIV and improve their reconstitution when antiretroviral is begun. He is also the principal investigator of a federally funded program of projects designed to determine barriers to HIV eradication. In addition, Dr. Schacker has established a collaboration with the Joint Clinical Research Center in Kampala, Uganda to study how constant exposure to common infections like tuberculosis, malaria, and helminthic infections affect rates of HIV transmission and progression.
Research Summary
IL-15 to Deplete HIV Reservoirs and Improve Immune Responses; Antifibrotic Therapy to Improve Immune Reconstitution in HIV
Research Funding Grants
- Predictors of Time to Viremia with an Analytic Treatment Interruption, amfAR, 109496-60-RGRL, Principal Investigator.
- Reservoir Dynamics in Patients Treated in Very Early Acute HIV Infection, NIH, R01 AI125127, Principal Investigator.
- Reversing Tissue Fibrosis to Improve Immune Reconstruction in HIV, NIH, U01AI105872, Principal Investigator.
- Antifibrotic Therapy to Improve Immune Reconstitution in HIV, NIH, R01 AI093319-01A1, Principal Investigator.
- IL-15 to Deplete HIV Reservoirs and Improve Immune Responses, Altor Bioscience, ALT-803, Principal Investigator.
Clinical Summary
HIV
Education
Honors and Recognition
Professional Memberships
Selected Publications


516 Delaware St SE
Minneapolis, MN 55455
Bio
Bevan Yueh, MD, MPH, is the Chief Executive Officer for the University of Minnesota Physicians and Vice Dean of Clinical Affairs for the University of Minnesota Medical School. He is the former chair of the Department of Otolaryngology, Head and Neck Surgery. He is a practicing Head and Neck surgeon focused on the ablation of Head and Neck cancers.Dr. Yueh graduated from Princeton University and attended Stanford Medical School. He did his residency and fellowship clinical training at Johns Hopkins University and completed a Robert Wood Johnson Clinical Scholar research fellowship at Yale University.
Administrative Assistant Name
Sheng Lee
Awards & Recognition
- Minnesota Monthly "Best Doctor" (2016-2018)
- Minnesota Monthly's Best Doctors for Women (2013-2018)
- Mpls.St. Paul Magazine "Top Doctor" (2012-2018)
- Best Doctors in America® (2011-2012, 2018)
- Member, Collegium Oto-Rhino-Laryngologicum Amicitiae Sacrum
- Honor Award, American Academy of Otolaryngology/Head and Neck Surgery
Professional Associations
- Senior Examiner, American Board of Otolaryngology
- Editorial Board, Archives of Otolaryngology, Head & Neck Surgery
- Editorial Board, Laryngoscope
- Advisory Council, National Institute of Deafness and Communication Disorders
Specialties
- Head and neck tumors
- Salivary gland tumors
- Thyroid tumors
Research Summary
Over 100 Publications
Clinical Summary
Clinics University of Minnesota Medical Center


516 Delaware St SE
Minneapolis, MN 55455
Bio
Administrative Contact: Stephanie Fawkes | sfawkes10@umphysicians.umn.edu
Awards & Recognition
- Castle Connolly Top Doctors in America (2011-2022)
- Minnesota Monthly Top Doctors (2014-2022)
- Minneapolis St. Paul Top Doctors ( 2012-2022)
- Minneapolis/St. Paul Business Journal Health Care Hero (2022)
- Advocates for Better Health, Charles Bolles Bolles-Rogers Award (2021)
- Surgical Educator of the Year, University of Minnesota Department of Surgery (2018)
- Minnesota Physicians Community Caregivers Volunteer Physicians (2020)
- Defense Meritorious Service Medal (2009)
Medical School
M.D., University of Kansas, School of Medicine, Kansas City, KS
Residency
Residency, University of Kansas, School of Medicine, Kansas City, KS (General Surgery)
Fellowship
Fellowship, University of Minnesota, Minneapolis, MN (Surgical Critical Care)
Research Summary
Expertise: Surgery, Surgical Oncology, Critical Care and Trauma, Pancreatitis and Transplant
Service Summary
- Member, Clinical Trials Steering Committee, U.S. Army Institute for Surgical Research
- Reviewer, National Institutes of Health
- Vice Chair, Perioperative Services and Quality
Clinical Summary
Acute care; Critical care; High risk surgery; Islet Transplant Surgery; Minimally Invasive Surgery; Surgery (gastrointestinal, hernia, splenic, skin and soft tissue, billiary, laparoscopic, high risk, acute care, emergency, trauma surgery); Surgical infectious diseases; Surgical treatment of chronic pancreatitis; Trauma Services


420 Delaware St. SE
Minneapolis, MN, 55455
Bio
Administrative Contact: Brittany Ernst | 612-625-4424 | swan1187@umn.edu
Research Summary
Mediators of Inflammation, Sepsis and Injury Response Surgical Infections Surgical Education
Clinical Summary
Acute Care Surgery; Critical Care Surgery; General surgery (e.g., gastrointestinal, hernia, splenic, skin and soft tissue, biliary, laparoscopic, and high risk emergency); Minimally Invasive Surgery; Surgical Critical Care; Trauma Surgery


Bio
Dr. Clohisy is a professor and chair of the Department of Orthopedic Surgery at the University of Minnesota and a member of the University of Minnesota Cancer Center. He specializes in musculoskeletal oncology with a focus on both primary and metastatic cancers of bone and the management of musculoskeletal problems in hemophilia.
His clinical research focuses on the effect of surgical treatment of skeletal metastasis on health status, and he has also researched the cellular mechanisms of tumor osteolysis and mechanisms of bone cancer pain. He is committed to advancing all levels of musculoskeletal education and has interest and experience in developing both outstanding community orthopedic surgeons and orthopedic clinician scientists. His research program has had NIH funding for 23 consecutive years and he currently leads an Academic Health Center NIH training grant for graduate and past doctoral students.
Expertise
- Orthopedics
- Cancer
Awards & Recognition
- Best Doctors in America®: 2007-2010, 2011-2012, 2013
- Mpls.St. Paul Magazine "Top Doctors:" 2009-2010, 2012-2015, 2020
- U.S. News & World Report Top Doctor: 2012
- Minnesota Monthly "Top Doctors:" 2014, 2018, 2020
Publications
View Dr. Clohisy's Publications on PubMed
Professional Associations
- Chair of the Department of Orthopedic Surgery
- Elected member of the University of Minnesota Physicians (UMP) Board of Directors, serves on the UMP Executive committee and Chairs the UMP Clinical Strategies Committee
- Member, American Board of Orthopaedic Surgery Board Exam Committee
- Member, American Orthopaedic Association Critical Issues Committee
- Member, American Academy of Orthopaedic Surgeons Communicative Cabinet and Council on Education.
Administrative Assistant
Connie Butterfuss
612-626-2817
butte152@umn.edu
Fax: 612-273-7959
Mailing Address
University of Minnesota
Department of Orthopedic Surgery
2450 Riverside Avenue South
Suite R200
Minneapolis, MN 55454
Research Summary
Research Interests
- Bone and Soft Tissue Neoplasms
- Osteolysis
- Osteoclasts
- Mouse Genetic Engineering
- Bone Cancer Pain
- Experimental Sarcoma Models
Clinical Summary
My passion is bringing cutting-edge techniques, compassion, and hope to orthopedic oncology patients and their families. I listen to my patient’s needs and work with them to create a care plan tailored to their unique situation. I enjoy getting to know my patients and improving their quality of life.
Board Certifications
American Board of Orthopaedic Surgery
Clinical Specialties
- Musculoskeletal oncology with focus on both primary and metastatic cancers of the bone
- Management of musculoskeletal problems in hemophilia
Clinical Interests
Musculoskeletal oncology with focus on both primary and metastatic cancers of the bone; Management of musculoskeletal problems in hemophilia
Hospital Privileges
University of Minnesota Masonic Children's Hospital; University of Minnesota Medical Center

Bio
Administrator Info
Name: Sarah Chapeau
Phone: 612-625-3654
Email: chape044@umn.edu
Fax: 612-626-3107
Mail: 420 Delaware Street SE, MMC 194, Minneapolis, MN 55455
Summary
Dr. Elizabeth Seaquist is the Nesbitt Chair and Head of the Department of Medicine. Awards recognizing her research and mentoring include the American Diabetes Association’s Transformative Woman in Diabetes Award in 2019 and the Albert Renold Award for Mentoring in 2020. She served as the President for Medicine and Science of the American Diabetes Association in 2014. As a clinical investigator, Dr. Seaquist is interested in hypoglycemia and the complications of diabetes. Her research focuses on the effect of diabetes on brain metabolism, structure, and function. She was the site investigator for the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE) study, and the Researching Cardiovascular Events with a Weekly Incretin in Diabetes (REWIND) study. She has an active clinical practice and is board certified in Internal Medicine and Endocrinology, Diabetes, and Metabolism.
Research Summary
- Impact of diabetes on cerebral structure and function
- Hypoglycemia in diabetes
Clinical Trials
- Cerebral Responses to Insulin-Induced Hypoglycemia
- Effect of Recurrent Hypoglycemia
Clinical Summary
- Management of type 1 and type 2 diabetes
- Complications of diabetes
- Hypoglycemia in diabetes
Education
Fellowships, Residencies, and Visiting Engagements
Honors and Recognition
Professional Memberships


420 Delaware Street SE,
Minneapolis, MN 55455
Bio
Dr. Clarence Shannon is an assistant professor in the University of Minnesota Department of Anesthesiology. He serves as the Associate Dean of Strategy and Innovation for the University of Minnesota Medical School, as well as the Academic and Medical Director for Chronic Pain Management at the Department of Anesthesiology.
Clinical Summary
Schedule an appointment with Dr. Shannon at the Clinic for Comprehensive Pain Management by calling 612-301-1425.
Education
Professional Memberships
Selected Presentations


Mayo Mail Code 484
420 Delaware Street SE
Minneapolis, MN 55455
Bio
Dr. Amanda Termuhlen joined the University of Minnesota Medical School in June 2018 as Associate Dean for Faculty Affairs. She is an internationally recognized expert in rare pediatric non-Hodgkin lymphoma, centering her research efforts on the late effects of cancer treatment in children and adolescents and clinical trials for lymphoma.
Administrator Information
Julie Bodurtha
Education
Fellowships, Residencies, and Visiting Engagements
Licensures and Certifications


Bio
Administrator Info
Name: Kelly LaPara
Email: schot014@umn.edu
Mail: 420 Washington Ave SE, MMC 194, Minneapolis, MN 55455
Summary
Obesity and cardiovascular disease are among the leading causes of morbidity and mortality worldwide. Our research focuses on the interplay between intermediary metabolism and these disease processes. Derangements in the processing of carbohydrates, fats, and amino acids are central drivers of disease pathogenesis, but the roles of another metabolic fuel class, ketone bodies, are less well understood. We use novel genetic mouse models with engineered deficiencies in ketone body metabolism to study the metabolic shifts that occur in response to obesity, cardiovascular disease, and dynamic environmental challenges. From these models, we have developed new perspectives of how metabolism adapts in obesity, diabetes, nonalcoholic fatty liver disease (NAFLD/NASH), and cardiomyopathy; how these adaptations ultimately prove deleterious, and how innovative and personalized nutritional and pharmacological therapies may mitigate these adverse responses.
We leverage recent advances in stable isotope tracer based NMR and mass spectrometry-based untargeted metabolomics technologies to study metabolism on a systems level, and we also employ established techniques in molecular cell biology and biochemistry to reveal phenotypic shifts at the cellular level. Complex in vivo phenotyping methodologies are strategically aligned with these sophisticated chemical profiling platforms to generate high resolution phenotypic pictures. In addition to our mouse studies, we perform studies in humans to learn how alterations of ketone metabolism and related pathways may serve as diagnostic biomarkers and therapeutic targets for obesity, diabetes, NAFLD/NASH, heart failure/CHF, and metabolic maladaptations that can occur in any disease state.
Teaching Summary
Metabolic Biochemistry
Clinical Summary
Heart Failure


Bio
Dr. Ingbar is the Principal Investigator for research training provided to pre-doctoral students and post-doctoral MD and PhD fellows through a NHLBI training grant.
Clinical Summary
Acute lung injury/ARDS; Respiratory failure; Pulmonary embolism; Hemoptysis; Critical care; Pulmonary edema

Bio
Administrator Info
Name: Mena Vue
Phone: 612-624-3189
Email: vuexx154@umn.edu
Mail: 420 Delaware St SE
MMC 284 Mayo
8284B (Campus Delivery Code)
Minneapolis, MN 55455
Summary
Dr. Mustapha went to University of California San Francisco School of Medicine and then completed her internal medicine and pediatric residency training at the University of Minnesota. She spent a year as Chief Resident in the Department of Pediatrics prior to joining the faculty in both the departments of Internal Medicine and Pediatrics, as a clinician educator and hospitalist. She is currently the Associate Program Director of the Med-Peds Residency Program and the Director of Clinical Coaching for the medical school. Her academic interests include both undergraduate and graduate medical education, with a focus on clinical performance and equity, diversity, and inclusion in the clinical learning environment.
Clinical Summary
Hospital medicine; Medical Education; Health Equity