Yue Chen

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Credentials

PhD

Research Summary

My long-term goal is to discover and characterize novel posttranslational modification (PTM) pathways that are involved in protein homeostasis, cellular signaling and epigenetic regulation. To achieve this goal, I develop and apply mass spectrometry-based quantitative and chemical proteomics technology as well as bioinformatic analysis tools for system-wide characterization of protein modification networks. My work employs both cellular and animal-based models that involve diverse biological applications including cancer, metabolic diseases, nutrition and aging.