Division Announcements and Accomplishments
Congratulations to the Hughey lab for their paper, 'Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice,' accepted by the American Journal of Physiology-Endocrinology and Metabolism
Congratulations to Eric Queathem for receiving a scholarship to attend the 14th annual NIDDK Course: Isotope Tracers in Metabolic Research: Principles and Practice of Kinetic Analysis.
- Congratulations to Alisa B. Nelson for defending her Ph.D. thesis entitled “Development and deployment of untargeted metabolomics pipelines to reveal molecular signatures of wellness”.
- Congratulations to Curtis Hughey, Patrycja Puchalska and Peter Crawford for their paper "Integrating the contributions of mitochondrial oxidative metabolism to lipotoxicity and inflammation in NAFLD pathogenesis"
Congratulations to Curtis Hughey for receiving an American Cancer Society Institutional Research Grant titled "Defining the Role of Methyl Donor Availability in Hepatocellular Carcinoma Pathophysiology and the Underlying Metabolic Remodeling".
Congratulations to Peter Crawford for co-authorship paper, “Krebs takes a turn at cell differentiation”.
Congratulations to David (Blake) Stagg for receiving the J. Jacob Kaplan Award, which recognizes outstanding research by undergraduate or graduate medical students in one of the following areas: cardiology, immunology in the diagnosis and treatment of cancer, and gastroenterology.
Congratulations to Alisa Nelson and members of the Crawford-Puchalska lab for their paper, “Artifactual fatty acid dimers mimic FAHFA signals in untargeted metabolomics pipelines”.
- Congratulations to Siyuan Liu (Hughey Lab) for receiving an award from the Undergraduate Research Opportunities Program (UROP) for his project entitled "Defining liver metabolic responses to dietary methionine restriction
- Congratulations to Alisa Nelson and members of the Crawford-Puchalska lab for their paper, “Acute aerobic exercise reveals FAHFAs distinguish the metabolomes of overweight and normal weight runners”.
- Congratulations to Patrycja Puchalska, Alisa Nelson, and Peter Crawford for co-authorship paper, "Ketone body oxidation increases cardiac endothelial cell proliferation".
- Congratulations to Ferrol Rome and Curtis Hughey for their paper “Disrupted liver oxidative metabolism in glycine N-methyltransferase-deficient mice is mitigated by dietary methionine restriction”
- Congratulations to Alisa Nelson for receiving the Outstanding Graduate Researcher Award for her abstract and presentation entitled “Acute exercise unveils serum metabolomics markers distinguishing overweight and normal weight runners” at the 2021 Hebbel Research Day
- Congratulations to Ferrol Rome for receiving the Outstanding Predoctoral Researcher Award for her abstract and presentation entitled “Disrupted Liver Metabolism in GNMT-Deficient Mice is Mitigated by Dietary Methionine Restriction” at the 2021 Hebbel Research Day
- Congratulations to Patrycja Puchalska and Peter Crawford for their paper, “Metabolic and Signaling Roles of Ketone Bodies in Health and Disease”.
- Congratulations to David (Blake) Stagg for defending his Ph.D. thesis entitled “The role of hepatocyte D-ß-hydroxybutyrate dehydrogenase in ketone body metabolism and liver health”.
- The Wernimont Lab welcomes Renee Mahr and Dr. Sereen Nashif to the group.
- Congratulations to Curtis Hughey for his co-authorship on, 'Regulation and role of glycophagy in skeletal muscle energy metabolism.'
- Dr. Sarah Wernimont was given the “Mead Johnson Nutrition Early Career Speaker Award” by the Perinatal Research Society during their Annual Meeting in St. Pete’s Beach, Florida.
Congratulations to Alisa Nelson for passing her oral PhD qualifying exam for her proposal entitled, 'Mapping metabolic pathways of insulin resistance in the liver microenvironment.' Strong work!
- Congratulations to Curtis Hughey for his co-authored paper, ‘Multitissue 2H/13C flux analysis reveals reciprocal upregulation of renal gluconeogenesis in hepatic PEPCK-C-knockout mice’
- Congratulations to David (Blake) Stagg and members of the Crawford-Puchalska lab for their paper, Diminished ketone interconversion, hepatic TCA cycle flux, and glucose production in D-β-hydroxybutyrate dehydrogenase hepatocyte-deficient mice.
The Crawford-Puchalska Lab welcomes Alisha Seay to the group!
- Congratulations to Greg Shobert (Hughey lab) for his presentation at the 2021 Virtual Undergraduate Research Symposium.
- Congratulations to David (Blake) Stagg for receiving the Jan Lunden Award!! The Jan Lunden Award honors outstanding research by a graduate or medical student in the field of molecular hepatology.
We welcome Sneha Jena, new research associate to the Wernimont lab!
- Congratulations to Gregory Shobert, Hughey lab, for receiving an award from the Undergraduate Research Opportunities Program (UROP). He is testing the role of hepatic gluconeogenesis in the liver-specific and muscular adaptations to exercise.
- Congratulations to Patrycja Puchalska and members of the Crawford-Puchalska lab for their paper, Determination of ketone bodies in biological samples via rapid UPLC-MS/MS
- The Crawford-Puchalska lab welcomes Jacob Gillingham to the team. He will be learning and applying targeted metabolomics and lipidomics analyses to mammalian tissue samples.
- Congratulations to Patrycja Puchalska and Peter Crawford for their co-authored paper, ‘Mitochondrial pyruvate carriers are required for myocardial stress adaptation.’
- Congratulations to the Crawford and Puchalska lab for receiving R01 AG069781, ‘Ketogenic Oscillations and Neurometabolic Healthspan,' an inter-institutional project with the University of Kansas Medical Center, with the lab of John Thyfault.
- Congratulations to the Crawford and Puchalska lab for receiving a renewal to R01 DK091538, 'Ketone body metabolism and integrated metabolic homeostasis.'
- Congratulations to the Crawford and Puchalska lab for receiving Academic Investment Research Program (AIRP) funding, ‘Engineering the inhospitable cancer niche via intercellular metabolic shuttles,’ a collaborative endeavor with Kaylee Schwertfeger, Department of Laboratory Medicine and Pathology, and David Wood, College of Science and Engineering.
- Congratulations to Sarah Wernimont for her co-authored paper, ‘Redesigned Care Delivery for Insulin-Requiring Diabetes in Pregnancy Improves Perinatal Glycemic Control While Reducing Neonatal Intensive Care Admissions, Length of Stay, and Costs.’
- Congratulations to Curtis Hughey for his co-authored paper, ‘Reciprocity Between Skeletal Muscle AMPK Deletion and Insulin Action in Diet-Induced Obese Mice.’
We welcome Sarah Wernimont, MD, PhD, Assistant Professor of Obstetrics, Gynecology and Women's Health to the Division of Molecular Medicine!
Alisa Nelson, PhD student in the Bioinformatics and Computational Biology Program (Crawford lab), is awarded a 2020-2021 Interdisciplinary Doctoral Fellowship. The Interdisciplinary Doctoral Fellowship (IDF) provides a unique opportunity for outstanding Ph.D. students who are engaged in interdisciplinary research to study with faculty at one of the University’s interdisciplinary research centers or institutes during the fellowship year. Ms. Nelson’s host center is the Institute for Engineering in Medicine. Congratulations, Alisa!
- Congratulations to Peter Crawford for his co-authored paper, ‘Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation.’
- Dr. Curtis Hughey collaborates on the publication, Reciprocity Between Skeletal Muscle AMPK Deletion and Insulin Action in Diet-Induced Obese Mice, in the journal Diabetes.
- Drs. Peter Crawford and Tim Griffin, professor of Biochemistry, Molecular biology, and Biophysics, obtained a $10,000 award from the UMN Office of Academic Clinical Affairs for the project, ‘Angiotensin Peptide Turnover And Flux In Covid-19 Pathogenesis.’
- Dr. Patrycja Puchalska was promoted to Assistant Professor, Division of Molecular Medicine. Dr. Puchalska will continue to develop innovative methods to apply targeted and untargeted metabolomics methodologies to reveal the metabolic origins of fatty liver disease. Congratulations, Patrycja!
Dr. Morwena Solivio joins the Hughey Lab. Welcome to the team, Morwena!