Takako Araki

Associate Professor of Medicine, Division of Diabetes, Endocrinology and Metabolism
Faculty, T32 Research Training Program
Preceptor, Medical Scientist Training Program (Combined MD/PhD Training Program)


Administrator Info
Email: endofixer@umn.edu

Dr. Takako Araki graduated from Nagasaki University School of Medicine in Nagasaki, Japan. She completed her Internal Medicine residency training and Endocrinology fellowship from Mount Sinai Beth Israel, NY. She also completed her postdoctoral and clinical fellow ship from Cedars-Sinai Medical Center, Los Angeles, CA in 2015. Dr. Araki is currently an Assistant Professor in Division of Endocrinology, Diabetes and Metabolism at University of Minnesota. Her research is focused on quality improvement of pituitary perioperative patient care and pituitary/neuroendocrine hormone regulations.

Research Summary

  • Gene regulations of pituitary/neuroendocrine tumors
  • Quality Improvement of Pituitary Preoperative Patient Care

Clinical Summary

  • Pituitary Disorders; Diabetes
  • Adrenal
  • Bone
  • Thyroid
  • Osteoporosis

Honors and Recognition

North American Skull Base Society Research Award 2021/2022 , North American Skull Base Society
Minnesota Monthly "Top Doctors"
Mitsui Awards and Scholarship, The Japanese Medical Society of America
Friedman Fellowship Award, Mount Sinai Beth Israel Medical Center
Selected Publications

Selected Publications

Araki, T., Sangtian, J., Ruanpeng, D., Tummala, R., Clark, B., Burmeister, L., Peterson, D., Venteicher, A. S., Kawakami, Y., 2021. Acute elevation of interleukin 6 and matrix metalloproteinase 9 during the onset of pituitary apoplexy in Cushing's disease.. Pituitary, 24 (6): 859-866.
doi: https://doi.org/10.1007/s11102-021-01157-0 PubMed ID: 34041660.
Araki, T., Tone, Y., Yamamoto, M., Kameda, H., Ben-Shlomo, A., Yamada, S., Takeshita, A., Yamamoto, M., Kawakami, Y., Tone, M., Melmed, S., 2021. Two Distinctive POMC Promoters Modify Gene Expression in Cushing Disease.. The Journal of clinical endocrinology and metabolism, 106 (9): e3346-e3363.
doi: https://doi.org/10.1210/clinem/dgab387 PubMed ID: 34061962.
Araki, T., Liu, X., Kameda, H., Tone, Y., Fukuoka, H., Tone, M., Melmed, S., 2017. EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis.. J. Endocr. Soc., 1 (2): 127-143.
Araki, T., Liu, N., Tone, Y., Cuevas-Ramos, D., Heltsey, R., Tone, M., Melmed, S., 2016. E2F1-mediated human POMC expression in ectopic Cushing’s syndrome. . Endocr Relat Cancer., 23 (11): 857-870.
Cuevas-Ramos, D., Hong, J., Ben-Shlomo, A., Tone, Y., Tone, M., Melmed, S., 2015. Cyclin E-mediated human proopiomelanocortin regulation as a therapeutic target for Cushing disease.. Journal of Clinical Endocrinology and Metabolism, 100 (7): 2557-64.
Grants and Patents

Grants and Patents

Selected Grants

Award: Mechanisms for post-COVID pituitary damage
Principal Investigator: Araki, Takako
Award Dates: 2021 - 2024