"It is not looking at different things;
it is looking at the same things differently."
- Marc Noël
Investigating how MINDSET impacts healing and well-being by studying the synergy of Brain-Body-Mind.
MINDSET is the conscious and unconscious choices we make about the way we think and what we believe, our awareness and expectations, and our attitude and outlook. Here in the Brain Body Mind Lab, we are driven to discover innovative treatments incorporating how mindset works in synergy with Brain-Body-Mind to help recovery, healing, function, empowerment, self-image, and with that, quality of life.
We all experience challenges related to our health at some point in our lives which affects our bodies, brains and our minds.
Medical professionals have been successful at solving problems associated with acute disease. However, issues associated with chronic disease and chronic pain management have proven to be more challenging. Consequently, many patients receiving conventional care are additionally turning to complementary and integrative approaches.
As various complementary and integrative approaches gain wider acceptance, it is important to better understand how they work, and subsequently identify patients who would benefit most from complementary and integrative approaches used in conjunction with conventional care.
Examples of our areas of interest:
- The effect of cognitive multisensory rehabilitation (focused on body awareness and quality of movement) to improve sensory and motor recovery in people with stroke;
- The impact of self-awareness techniques through breathing or movement in people with stroke;
- Develop outcome measures to assess body awareness and quality of movement of the upper limb in people with stroke;
- Improve outcome measurements for body awareness and body image;
- Investigate how Qigong practice mediates changes brain function and affects overall health in people with chronic diseases and chronic pain;
- Determine the efficacy of using apps for mindfulness in daily life in combination with mindfulness treatment to improve quality of life in people with chronic pain;
- Identify how a change in mindset causes changes in brain function and affects overall health in people with chronic diseases.
"All revolutionary changes are unthinkable until they happen,
and then they are understood to be inevitable."
- Theodore Roszak
This is a new frontier in rehabilitation. If you would like to learn more or get involved in our journey of discovery, please click the appropriate link below.
- Current Studies
Kim S, Van de Winckel A, Shan P, Thompson K. Book Chapter Complementary Integrative Therapies. In: Textbook of Traumatic Brain Injury. Eds, Zasler ND, Katz D, Zafonte R. Accepted - to be published Jan 2021.
Larson M, Chantigian D, Asirvatham-Jeyaraj N, Van de Winckel A, Keller-Ross ML. Slow-paced breathing and autonomic function in people post-stroke. Frontiers in Physiology, section Clinical and Translational Physiology. 2020. In press.
Van de Winckel, A., De Patre, D., Rigoni, M., Fiecas, M., Hendrickson, T.J., Larson, M., Jagadeesan, B.D., Mueller, B.A., Elvendahl, W., Streib, C., Ikramuddin, F., Lim, K.O. Exploratory study of how cognitive multisensory rehabilitation restores parietal operculum connectivity and improves upper limb movements in chronic stroke. 10 September 2020, PREPRINT available at Research Square https://doi.org/10.21203/rs.3.rs-75235/v1.
Van de Winckel A, Nawshin T, Byron C. Exploratory Study for Using the mobile Hudl App with Telehealth: A Randomized Controlled Trial Shows Positive Impact on Home Exercise Program Adherence in People with Chronic Diseases and in Financial Distress. (Preprint). DOI: 10.2196/preprints.22659. JMIR. 2020.
Dawson J, MD; Engineer ND, Prudente CN, Pierce D, Francisco G, Yozbatiran N, PhD3; Tarver B, Casavant R, Kline D, Cramer SC, Van de Winckel A, Kimberley TJ. Vagus Nerve Stimulation Paired with Upper Limb Rehabilitation after Stroke: One-year Follow-up. Neurorehab Neural Repair. 2020 Jul;34(7):609-615. doi: 10.1177/1545968320924361.
Van de Winckel A, Gauthier L. A revised Motor Activity Log following Rasch validation (Rasch-based MAL-18) and consensus methods in chronic stroke and multiple sclerosis. Neurorehabil Neural Repair 2019, 33(10):787–791.
Grampurohit N, Van de Winckel A, Ehrlich-Jones L. Measurement Characteristics and Clinical Utility of the ABILHAND-KIDS for children with neuromuscular conditions. Arch Phys Med Rehabil. 2019, 100(9):1795–1796.
Van de Winckel A, Ottiger B, Bohlhalter S, Nyffeler T, Vanbellingen T. Comprehensive ADL outcome measurement after stroke: Rasch validation of the Lucerne ICF-based Multidisciplinary Observation Scale (LIMOS). Arch Phys Med Rehabil. 2019, 100(12):2314-2323.
Van de Winckel A, Carey JR, Bisson TA, Hauschildt E, Streib C, Durfee W. Safety and Feasibility of Transcranial Direct Current Stimulation via Telerehabilitation in People with Stroke. Arch Phys Med Rehabil. 2018, 99(10):e74.
Van de Winckel A, Carey JR, Bisson TA, Hauschildt EC, Durfee WK. Home-Based Transcranial Direct Current Stimulation plus Tracking Training Therapy in People with Stroke: An Open-Label Feasibility Study. J NeuroEng Rehab. 2018, 15:83. https://doi.org/10.1186/s12984-018-0427-2
Van de Winckel A, Ehrlich-Jones L. Measurement Characteristics and Clinical Utility of the Motor Evaluation Scale for Upper Extremity in Stroke Patients. Arch Phys Med Rehabil. 2018, 99(12):2657-2658. https://doi.org/10.1016/j.apmr.2018.08.176.
Van de Winckel A, Jarrar M, Grampurohit N, Ehrlich-Jones L. Measurement Characteristics and Clinical Utility of the ABILHAND Among People With Rheumatoid Arthritis. Arch Phys Med Rehabil. 2018, 99(8):1693–1694. https://doi.org/10.1016/j.apmr.2018.04.006.
Frost KL, Chen M, Cassidy JM, Snow L, Hodges JS, Van de Winckel A, Kimberley TJK, Carey JR. Paired Associative Stimulation to Suppress Contralesional Corticospinal Excitability in Three People with Stroke Using N-of-1 Crossover Design. J Neurol Transl Neurosci. 2017, 5(2): 1084.
Van de Winckel A, Tseng YT, Chantigian D, Lorant K, Zarandi Z, Buchannan J, Zeffiro TA, Larson M, Olson-Kellogg B, Konczak J, Keller-Ross M. Age-Related Decline of Wrist Position Sense and its Relationship to Specific Physical Training. Frontiers Hum Neurosci. 2017, 11:570. doi: 10.3389/fnhum.2017.00570.
Van de Winckel A, Tseng Y.T., Chantigian D,Lorant K, Zarandi Z, Buchanan J, Konczak J, Zeffiro T, Olson-Kellogg B, Larson M, Keller-Ross M. Mapping Age-Related Changes in Wrist Proprioception. Arch Phys Med Rehabil. 2017, 98(10):e80-e81.
De Patre D, Van de Winckel A*, Panté F, Rizzello C, Zernitz M, Mansour M, Zordan L, Zeffiro T, O’Connor EE, Bisson T, Lupi A, Perfetti C. A case report of visual and motor recovery after 8 months of "cognitive therapeutic exercises" in cortical blindness. JNPT. 2017, 41(3):164-172. doi: 10.1097/NPT.0000000000000189. *shared first author
De Patre D, Van de Winckel A. Strategies for Scientific Research in Neurocognitive Rehabilitation Riabilitazione Neurocognitiva. 2016, (3):216-229.
Krewer K, Van de Winckel A, Elangovan N, Aman JE, Konczak J. Commentary on: "Assessing proprioception: A critical review of methods" by Han et al. (2015). JSHS. 2016, 5(1):91-92.
Van de Winckel A, Verheyden G, Wenderoth N, Peeters R, Sunaert S, Van Hecke W, Perfetti C, De Cock P, Desloovere K, Eyssen M, Feys H. Does somatosensory discrimination activate different brain areas in children with unilateral cerebral palsy compared to typically developing children? An fMRI study. Res Dev Dis. 2013, 34(5):1710-1720. doi: 10.1016/j.ridd.2013.02.017.
Van de Winckel A, Klingels K, Bruyninckx F, Wenderoth N, Peeters R, Sunaert S, Van Hecke W, De Cock P, Eyssen M, De Weerdt W, Feys H. How does brain activation differ in children with unilateral cerebral palsy compared to typically developing children during active and passive movements, and tactile stimulation? An fMRI study. Res Dev Dis. 2013, 34(1):183–197. doi: 10.1016/j.ridd.2012.07.030.
Van de Winckel A, Wenderoth N, Feys H, Sunaert S, Peeters R, Thijs V, Swinnen S, Perfetti C, De Weerdt W. Frontoparietal involvement in passively guided shape and length discrimination: A comparison between subcortical stroke patients and healthy controls. Exp Brain Res. 2012, 220(2):179-189. doi: 10.1007/s00221-012-3128-2.
Klingels K, Feys H, De Wit L, Jaspers E, Van de Winckel A, Verbeke G, De Cock P, Molenaers G. Arm and hand function in children with unilateral cerebral palsy: A one-year follow-up study. Eur J Paediatr Neurol. 2012, 16(3):257-265. doi: 10.1016/j.ejpn.2011.08.001.
Verhoeven J, Rommel N, Prodi E, Leemans A, Zink I, Vandewalle E, Noens I, Wagemans J, Steyaert J, Boets B, Van de Winckel A, Decock P, Sunaert S. Is there a common neuro-anatomical substrate of language deficit between Autism Spectrum Disorder and Specific Language Impairment? Cereb Cortex. 2012, 22(10):2263-2271. doi: 10.1093/cercor/bhr292.
Vanbellingen T, Kersten B, Van de Winckel A, Bellion M, Baronti F, Müri R, Bohlhalter S. A new bedside test of gestures in stroke: The apraxia screen of TULIA (AST). J Neurol Neurosurg Psychiatry. 2011, 82(4):389-392. doi: 10.1136/jnnp.2010.213371.
Klingels K, Jaspers E, Van de Winckel A, Huysmans A, Feys H. A systematic review of arm activity measures for children with hemiplegic cerebral palsy. Clin Rehabil. 2010, 24(10):887-900. doi: 10.1177/0269215510367994.
Vanbellingen T, Kersten B, Van Hemelrijk B, Van de Winckel A, Bertschi M, Müri R, De Weerdt W, Bohlhalter S. Comprehensive assessment of gesture production: a new test of upper limb apraxia (TULIA). Eur J Neurol. 2010, 17(1):59-66. doi: 10.1111/j.1468-1331.2009.02741.x.
Van de Winckel A, Feys H, Lincoln N, De Weerdt W. Assessment of arm function in stroke patients: Rivermead Motor Assessment arm section revised with Rasch analysis. Clin Rehabil. 2007, 21(5):471-479.
Verheyden G, Nieuwboer A, Van de Winckel A, De Weerdt W. Clinical tools to measure trunk performance after stroke: a systematic review of the literature. Clin Rehabil. 2007, 21(5):387-394.
Van de Winckel A, Feys H, van der Knaap S, Messerli R, Baronti F, Lehmann R, Van Hemelrijk B, Pante F, Perfetti C, De Weerdt W. Can quality of movement be measured? Rasch analysis and inter-rater reliability of the Motor Evaluation Scale for Upper Extremity in Stroke Patients (MESUPES). Clin Rehabil. 2006, 20(10):871-884.
Van de Winckel A. Commentary on "Physiotherapy assessment of knee proprioception following stroke" by Piriyaprasarth et al (2006). IJTR. 2006, 13(10):456.
Van de Winckel A, Sunaert S, Wenderoth N, Peeters R, Van Hecke P, Feys H, Horemans E, Marchal G, Swinnen S, Perfetti C, De Weerdt W. Passive Somatosensory Discrimination Tasks in Healthy Volunteers: differential networks involved in familiar versus unfamiliar shape and length discrimination. NeuroImage. 2005, 26(2):441-453.
Van de Winckel A, Feys H, De Weerdt W, Dom R. Cognitive and behavioral effects of music-based exercises in patients with dementia. Clin Rehabil. 2004, 18(3):253-260.
De Weerdt W, Nuyens G, Feys H, Van Gronsveld P, Van de Winckel A, Nieuwboer A, Osaer J, Kiekens C. Group Physiotherapy improves time use by patients with stroke in rehabilitation. Aust J Physiother. 2001, 47(1):53-61.
De Weerdt W, Selz B, Nuyens G, Staes F, Swinnen D, Van de Winckel A, Nieuwboer A, Lysens R, Feys H. Time use of stroke patients in an intensive rehabilitation unit: A comparison between a Belgian and a Swiss setting. Disabil Rehabil. 2000, 22(4):181-186.
Feys H, De Weerdt W, Nuyens G, Selz B, Van de Winckel A, Kiekens C. Predicting motor recovery of the upper limb following stroke rehabilitation: value of a clinical examination. Physiother Res Int. 2000, 5(1):1-18.
Elite Reviewer for 2019 for the Archives of Physical Medicine and Rehabilitation
Training in Grantsmanship for Rehabilitation Research (TIGRR) Fellowship, 2019-2020 (Sponsored by NIH/NICHD)
APTA Early Career Award, 2016
Training in Grantsmanship for Rehabilitation Research (TIGRR) Fellowship, 2014
Identifying brain mechanisms of cognitive multisensory rehabilitation for neuropathic pain relief in adults with spinal cord injury
Funding: 2020 Academic Investment Research Program (AIRP)
Role: Co-PI (with Dr Leslie Morse)
Feasibility of identifying brain mechanisms of Qigong and behavioral outcomes after Qigong practice in people with chronic low back pain
Funding: 2019 Clinical Translational Research Services (CTRS) Pilot Funding Program
Timeline: September 2019 - August 2021
Role: Principal Investigator
A Randomized Pilot Study Assessing Vagus Nerve Stimulation (VNS) During Rehabilitation for Improved Upper Limb Motor Function after Stroke (MicroTransponder's Vivistim System)
Funding: Microtransponder Inc. (Study MT-St-02 Stroke)
Timeline: April 2015 – December 2018 (projected towards 2020)
Role: Principal Investigator (8/18/2017-present); Co-PI (7/7/2017-8/17/2017)
fMRI compatible robot
Clinical assessment batteries
Therapy material for cognitive multisensory rehabilitation (also known as "cognitive therapeutic exercises")
The MotionMonitor by Innovative Sports Training, Inc.