Brain Body Mind Lab Members

Research Summary

Research Summary/Interests

Dr. Ann Van de Winckel, PhD, MSPT, PT is Assistant Professor at the Medical School of the University of Minnesota in the Department of Rehabilitation Medicine (Division of Physical Therapy, and Division of Rehabilitation Science). She is also the Director of the Brain Body Mind Lab. 

The main research focus of her lab is to investigate the brain mechanisms of body awareness in physical therapy (cognitive multisensory rehabilitation or CMR) as well as mind and body approaches (such as Qigong) to improve health and daily life function in people with chronic neurological conditions and/or chronic pain. Her lab made a crucial discovery that focus on body awareness using CMR led to restoration of the disrupted parietal operculum network in adults with chronic stroke, in parallel with long-lasting improved upper limb sensorimotor function. Her studies of CMR on reducing neuropathic pain and improving sensorimotor function in other neurological conditions such as adults with spinal cord injury have led to long-lasting significant neuropathic pain reduction and improved sensation and movement. Those sensorimotor improvements were paired with significant improvements in brain function. Since mind and body approaches have been shown to improve body awareness and reduce pain, she also investigated the effect of Qigong on body awareness-related brain functions in adults with chronic low back pain and adults with neurological conditions such as adults with spinal cord injury with and without neuropathic pain with significant lasting reduction in chronic pain. Her long-term goals are to investigate the interactions between body awareness, physical impairments, and psychological factors such as mindset (brain-body-mind interactions) to facilitate development and implementation of new rehabilitation strategies that attend to these factors to provide pain relief and increased health and functional recovery in adults with chronic neurological conditions and/or chronic pain.

Research Funding Grants

Remotely delivered Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery after Spinal Cord Injury

• Funding: Minnesota Spinal Cord Injury and Traumatic Brain Injury Research Grant Program 2022
• Timeline: 10/1/2022-9/31/2024
• Role: Principal Investigator

A Clinical Trial of Cognitive Multisensory Rehabilitation for Sensory and Motor Recovery in Adults with Spinal Cord Injury

• Funding: Paralyzed Veterans of America
• Timeline: 1/1/2022-12/31/2023
• Role: Principal Investigator

Minnesota Regional Spinal Cord Injury Model System

• Funding: NIDILRR Department of Health and Human Services
• Timeline: 9/1/2021-8/31/2025
• Role: Co-Investigator

Identifying brain mechanisms of cognitive multisensory rehabilitation for neuropathic pain relief in adults with spinal cord injury

• Funding: Academic Investment Research Program (AIRP)
• Timeline: 9/1/2020-8/31/2022
• Role: Co-Investigator

Knowledge Translation to Promote Patient-Centered Care through Use of Standardized Assessments

• Funding: National Institute on Disability, Independent Living, and Rehabilitation Research
• Timeline: 10/1/2020-9/30/2025
• Role: Advisory Committee

A Randomized Pilot Study Assessing Vagus Nerve Stimulation (VNS) During Rehabilitation for Improved Upper Limb Motor Function after Stroke (MicroTransponder's Vivistim System)

• Funding: Microtransponder Inc. (Study MT-St-02 Stroke)
• Timeline: 12/1/2014-3/31/2022
• Role: Principal Investigator (8/18/2017-3/31/2022); Co-PI (7/7/2017-8/17/2017)

Feasibility of identifying brain mechanisms of Qigong and behavioral outcomes after Qigong practice in people with chronic low back pain

• Funding: 2019 Clinical Translational Research Services (CTRS) Pilot Funding Program
• Timeline: 9/1/19 - 2/28/2022
• Role: Principal Investigator

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Publications

2023

• Van de Winckel A, Carpentier ST, Deng W, Zhang L, Philippus A, Monden KR, Battaglino R, Morse LR. Using remotely delivered Spring Forest Qigong™ to reduce neuropathic pain in adults with spinal cord injury: A non-randomized controlled trial. medRxiv [Preprint]. 2023 Feb 15:2023.02.11.23285793. doi: 10.1101/2023.02.11.23285793. PMID: 36824929; PMCID: PMC9949188 
• Van de Winckel A, Zhang L, Hendrickson T, Lim KO, Mueller BA, Philippus A, Monden KR, Oh J, Huang Q, Ruen J, Konczak J, Evans R, Bronfort G. Identifying body awareness-related brain network changes after Spring Forest Qigong™ practice or P.Volve low-intensity exercise in adults with chronic low back pain: a feasibility Phase I Randomized Clinical Trial. medRxiv [Preprint]. 2023 Feb 14:2023.02.11.23285808. doi: 10.1101/2023.02.11.23285808. PMID: 36824785; PMCID: PMC9949220.
• Van de Winckel A, Carpentier ST, Deng W, Bottale S, Zhang L, Hendrickson T, Linnman C, Lim KO, Mueller BA, Philippus A, Monden KR, Wudlick R, Battaglino R, Morse LR. Identifying Body Awareness-Related Brain Network Changes after Cognitive Multisensory Rehabilitation for Neuropathic Pain Relief in Adults with Spinal Cord Injury: Delayed Treatment arm Phase I Randomized Controlled Trial. medRxiv [Preprint]. 2023 Feb 10:2023.02.09.23285713. doi: 10.1101/2023.02.09.23285713. PMID: 36798345; PMCID: PMC9934787.
• Deng W, Carpentier S, Blackwood J, Van de Winckel A. Rasch validation of the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS) in community-dwelling adults. BMC Psychol. 2023 Feb 17;11(1):48. doi: 10.1186/s40359-023-01058-w. PMID: 36803574; PMCID: PMC9936469.
• Deng W, Carpentier S, Van de Winckel A. Physical body experiences questionnaire simplified for active aging (PBE-QAG): Rasch validation. PLoS One. 2023 Feb 10;18(2):e0280198. doi: 10.1371/journal.pone.0280198. PMID: 36763606; PMCID: PMC9916545.
• Blackwood J, Carpentier S, Deng W, Van de Winckel A. Preliminary Rasch analysis of the Multidimensional Assessment of Interoceptive Awareness in adults with stroke. PLoS One. 2023. In press. 

• Francisco GE, Engineer ND, Dawson J, Kimberley TJ, Cramer SC, Prudente CN, Pierce D, Tarver WB, Hinds RHA, Van de Winckel A, Yozbatiran N. Vagus Nerve Stimulation Paired With Upper-Limb Rehabilitation After Stroke: 2- and 3-Year Follow-up From the Pilot Study. Arch Phys Med Rehabil. 2023 Mar 30:S0003-9993(23)00147-8. doi: 10.1016/j.apmr.2023.02.012. PMID: 37001842.

2022

•  Hartman J, Sharp A, Van de Winckel A, Tetreault K, & Pechak C. (2022). Exploring the Characteristics of Doctor of Physical Therapy Students Intending to Work in Medically Underserved Areas. Journal of Health Care for the Poor and Underserved 33(3), 1368-1382. doi:10.1353/hpu.2022.0118.
• Mallinson T, Kozlowski AJ, Johnston MV, Weaver J, Terhorst L, Grampurohit N, Juengst S, Ehrlich-Jones L, Heinemann AW, Melvin J, Sood P, Van de Winckel A. Rasch Reporting Guideline for Rehabilitation Research (RULER): the RULER Statement. Arch Phys Med Rehabil. 2022 Jul;103(7):1477-1486. doi: 10.1016/j.apmr.2022.03.013. Epub 2022 Apr 12. PMID: 35421395.
• Van de Winckel A, Kozlowski AJ, Johnston MV, Weaver J, Grampurohit N, Terhorst L, Juengst S, Ehrlich-Jones L, Heinemann AW, Melvin J, Sood P, Mallinson T. Reporting Guideline for RULER: Rasch Reporting Guideline for Rehabilitation Research: Explanation and Elaboration. Arch Phys Med Rehabil. 2022 Jul;103(7):1487-1498. doi: 10.1016/j.apmr.2022.03.019. Epub 2022 Apr 15. PMID: 35436496.
• Van de Winckel A, Carpentier S, Deng W, Bottale S, Hendrickson T, Zhang L, Wudlick R, Linnman C, Battaglino R, Morse L. Identifying body awareness-related brain network changes after cognitive multisensory rehabilitation for reduced neuropathic pain in adults with spinal cord injury: Protocol of the pilot clinical trial. TSCIR. 2022.

2021

• Kim S, Van de Winckel A, Thompson KL, Heyn P. Book Chapter 78 Complementary and Integrative Medicine in Brain Injury Medicine, Principles and Practice, Third Edition, editors: Nathan D. Zasler MD; Douglas I. Katz MD; Ross D. Zafonte DO
• Van de Winckel A, Nawshin T, Byron C. Exploratory Study for Using the mobile Hudl App with Telehealth: A Randomized Controlled Trial Shows Positive Impact on Home Exercise Program Adherence in People with Chronic Diseases and in Financial Distress. JMIR Formative Research 2021;5(3):e22659. doi: 10.2196/22659
• Sharp A, Schmidt A, Casto C, Van de Winckel A. Lapses in Professional Behavior Identified by Students of Physical Therapy. JAH. 2021. J Allied Health 2021;50(2):e53-e57.

2020

• Van de Winckel A, De Patre D, Rigoni M, Fiecas M, Hendrickson TJ, Larson M, Jagadeesan BD, Mueller BA, Elvendahl W, Streib C, Ikramuddin F, Lim KO. Exploratory study of how Cognitive Multisensory Rehabilitation restores parietal operculum connectivity and improves upper limb movements in chronic stroke. Sci Rep. 2020 Nov 20;10(1):20278. DOI: 10.1038/s41598-020-77272-y. PMID: 33219267
• Larson M, Chantigian DP, Asirvatham-Jeyaraj N, Van de Winckel A, Keller-Ross ML. Slow-Paced Breathing and Autonomic Function in People Post-stroke. Front Physiol. 2020 Oct 30;11:573325. doi: 10.3389/fphys.2020.573325. eCollection 2020. PMID: 33192570
• Dawson J, Engineer ND, Prudente CN, Pierce D, Francisco G, Yozbatiran N, Tarver B, Casavant R, Kline D, Cramer SC, Van de Winckel A, Kimberley TJ. Vagus Nerve Stimulation Paired with Upper Limb Rehabilitation after Stroke: One-year Follow-up. Neurorehab Neural Repair. 2020 Jul;34(7):609-615. DOI: 10.1177/1545968320924361.

2019

• Van de Winckel A, Gauthier L. A revised Motor Activity Log following Rasch validation (Rasch-based MAL-18) and consensus methods in chronic stroke and multiple sclerosis. Neurorehabil Neural Repair 2019, 33(10):787–791
• Grampurohit N, Van de Winckel A, Ehrlich-Jones L. Measurement Characteristics and Clinical Utility of the ABILHAND-KIDS for children with neuromuscular conditions. Arch Phys Med Rehabil. 2019, 100(9):1795–1796
• Van de Winckel A, Ottiger B, Bohlhalter S, Nyffeler T, Vanbellingen T. Comprehensive ADL outcome measurement after stroke: Rasch validation of the Lucerne ICF-based Multidisciplinary Observation Scale (LIMOS). Arch Phys Med Rehabil. 2019, 100(12):2314-2323.

2018

• Van de Winckel A, Carey JR, Bisson TA, Hauschildt E, Streib C, Durfee W. Safety and Feasibility of Transcranial Direct Current Stimulation via Telerehabilitation in People with Stroke. Arch Phys Med Rehabil. 2018, 99(10):e74
• Van de Winckel A, Carey JR, Bisson TA, Hauschildt EC, Durfee WK. Home-Based Transcranial Direct Current Stimulation plus Tracking Training Therapy in People with Stroke: An Open-Label Feasibility Study. J NeuroEng Rehab. 2018, 15:83. https://doi.org/10.1186/s12984-018-0427-2
• Van de Winckel A, Ehrlich-Jones L. Measurement Characteristics and Clinical Utility of the Motor Evaluation Scale for Upper Extremity in Stroke Patients. Arch Phys Med Rehabil. 2018, 99(12):2657-2658. https://doi.org/10.1016/j.apmr.2018.08.176
• Van de Winckel A, Jarrar M, Grampurohit N, Ehrlich-Jones L. Measurement Characteristics and Clinical Utility of the ABILHAND Among People With Rheumatoid Arthritis. Arch Phys Med Rehabil. 2018, 99(8):1693–1694. https://doi.org/10.1016/j.apmr.2018.04.006.

2017

• Frost KL, Chen M, Cassidy JM, Snow L, Hodges JS, Van de Winckel A, Kimberley TJK, Carey JR. Paired Associative Stimulation to Suppress Contralesional Corticospinal Excitability in Three People with Stroke Using N-of-1 Crossover Design. J Neurol Transl Neurosci. 2017, 5(2): 1084
• Van de Winckel A, Tseng YT, Chantigian D, Lorant K, Zarandi Z, Buchannan J, Zeffiro TA, Larson M, Olson-Kellogg B, Konczak J, Keller-Ross M. Age-Related Decline of Wrist Position Sense and its Relationship to Specific Physical Training. Frontiers Hum Neurosci. 2017, 11:570. doi: 10.3389/fnhum.2017.00570
• Van de Winckel A, Tseng Y.T., Chantigian D,Lorant K, Zarandi Z, Buchanan J, Konczak J, Zeffiro T, Olson-Kellogg B, Larson M, Keller-Ross M. Mapping Age-Related Changes in Wrist Proprioception. Arch Phys Med Rehabil. 2017, 98(10):e80-e81
• De Patre D, Van de Winckel A*, Panté F, Rizzello C, Zernitz M, Mansour M, Zordan L, Zeffiro T, O’Connor EE, Bisson T, Lupi A, Perfetti C. A case report of visual and motor recovery after 8 months of "cognitive therapeutic exercises" in cortical blindness. JNPT. 2017, 41(3):164-172. doi: 10.1097/NPT.0000000000000189. *shared first author.

2016

• De Patre D, Van de Winckel A. Strategies for Scientific Research in Neurocognitive Rehabilitation Riabilitazione Neurocognitiva. 2016, (3):216-229
• Krewer K, Van de Winckel A, Elangovan N, Aman JE, Konczak J. Commentary on: "Assessing proprioception: A critical review of methods" by Han et al. (2015). JSHS. 2016, 5(1):91-92.

2013

• Van de Winckel A, Verheyden G, Wenderoth N, Peeters R, Sunaert S, Van Hecke W, Perfetti C, De Cock P, Desloovere K, Eyssen M, Feys H. Does somatosensory discrimination activate different brain areas in children with unilateral cerebral palsy compared to typically developing children? An fMRI study. Res Dev Dis. 2013, 34(5):1710-1720. doi: 10.1016/j.ridd.2013.02.017
• Van de Winckel A, Klingels K, Bruyninckx F, Wenderoth N, Peeters R, Sunaert S, Van Hecke W, De Cock P, Eyssen M, De Weerdt W, Feys H. How does brain activation differ in children with unilateral cerebral palsy compared to typically developing children during active and passive movements, and tactile stimulation? An fMRI study. Res Dev Dis. 2013, 34(1):183–197. doi: 10.1016/j.ridd.2012.07.030.

2012

• Van de Winckel A, Wenderoth N, Feys H, Sunaert S, Peeters R, Thijs V, Swinnen S, Perfetti C, De Weerdt W. Frontoparietal involvement in passively guided shape and length discrimination: A comparison between subcortical stroke patients and healthy controls. Exp Brain Res. 2012, 220(2):179-189. doi: 10.1007/s00221-012-3128-2
• Klingels K, Feys H, De Wit L, Jaspers E, Van de Winckel A, Verbeke G, De Cock P, Molenaers G. Arm and hand function in children with unilateral cerebral palsy: A one-year follow-up study. Eur J Paediatr Neurol. 2012, 16(3):257-265. doi: 10.1016/j.ejpn.2011.08.001
• Verhoeven J, Rommel N, Prodi E, Leemans A, Zink I, Vandewalle E, Noens I, Wagemans J, Steyaert J, Boets B, Van de Winckel A, Decock P, Sunaert S. Is there a common neuro-anatomical substrate of language deficit between Autism Spectrum Disorder and Specific Language Impairment? Cereb Cortex. 2012, 22(10):2263-2271. doi: 10.1093/cercor/bhr292.

2011

• Vanbellingen T, Kersten B, Van de Winckel A, Bellion M, Baronti F, Müri R, Bohlhalter S. A new bedside test of gestures in stroke: The apraxia screen of TULIA (AST). J Neurol Neurosurg Psychiatry. 2011, 82(4):389-392. doi: 10.1136/jnnp.2010.213371.

2010

• Klingels K, Jaspers E, Van de Winckel A, Huysmans A, Feys H. A systematic review of arm activity measures for children with hemiplegic cerebral palsy. Clin Rehabil. 2010, 24(10):887-900. doi: 10.1177/0269215510367994
• Vanbellingen T, Kersten B, Van Hemelrijk B, Van de Winckel A, Bertschi M, Müri R, De Weerdt W, Bohlhalter S. Comprehensive assessment of gesture production: a new test of upper limb apraxia (TULIA). Eur J Neurol. 2010, 17(1):59-66. doi: 10.1111/j.1468-1331.2009.02741.x.

2007

• Van de Winckel A, Feys H, Lincoln N, De Weerdt W. Assessment of arm function in stroke patients: Rivermead Motor Assessment arm section revised with Rasch analysis. Clin Rehabil. 2007, 21(5):471-479.
• Verheyden G, Nieuwboer A, Van de Winckel A, De Weerdt W. Clinical tools to measure trunk performance after stroke: a systematic review of the literature. Clin Rehabil. 2007, 21(5):387-394.

2006

• Van de Winckel A, Feys H, van der Knaap S, Messerli R, Baronti F, Lehmann R, Van Hemelrijk B, Pante F, Perfetti C, De Weerdt W. Can quality of movement be measured? Rasch analysis and inter-rater reliability of the Motor Evaluation Scale for Upper Extremity in Stroke Patients (MESUPES). Clin Rehabil. 2006, 20(10):871-884
• Van de Winckel A. Commentary on "Physiotherapy assessment of knee proprioception following stroke" by Piriyaprasarth et al (2006). IJTR. 2006, 13(10):456.

2005

• Van de Winckel A, Sunaert S, Wenderoth N, Peeters R, Van Hecke P, Feys H, Horemans E, Marchal G, Swinnen S, Perfetti C, De Weerdt W. Passive Somatosensory Discrimination Tasks in Healthy Volunteers: differential networks involved in familiar versus unfamiliar shape and length discrimination. NeuroImage. 2005, 26(2):441-453.

2004

• Van de Winckel A, Feys H, De Weerdt W, Dom R. Cognitive and behavioral effects of music-based exercises in patients with dementia. Clin Rehabil. 2004, 18(3):253-260.

2001

• De Weerdt W, Nuyens G, Feys H, Van Gronsveld P, Van de Winckel A, Nieuwboer A, Osaer J, Kiekens C. Group Physiotherapy improves time use by patients with stroke in rehabilitation. Aust J Physiother. 2001, 47(1):53-61.

2000

• De Weerdt W, Selz B, Nuyens G, Staes F, Swinnen D, Van de Winckel A, Nieuwboer A, Lysens R, Feys H. Time use of stroke patients in an intensive rehabilitation unit: A comparison between a Belgian and a Swiss setting. Disabil Rehabil. 2000, 22(4):181-186
• Feys H, De Weerdt W, Nuyens G, Selz B, Van de Winckel A, Kiekens C. Predicting motor recovery of the upper limb following stroke rehabilitation: value of a clinical examination. Physiother Res Int. 2000, 5(1):1-18.

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Teaching Summary

Courses

• CPMS 5101 Clinical Physiology and Movement Science (guest lecture)
• PT 6287 Neurorehabilitation (guest lecture)
• PT 6293 Essentials of Rehabilitation Research
• PT 8132 Research Seminar I
• PT 8193 Research Problems
• RSC 5106 Introduction to Rehabilitation Science
• RSC 8130 Current literature in Rehabilitation Science
• RSC 5294 Independent study in Rehabilitation Science
• RSC 8192 Research Design in Rehabilitation Science

Clinical Summary

Board Certifications

• Certified for AHA assessment for children with cerebral palsy (rater n° 579), 2009-present
• US Licensure Physical Therapy - Minnesota (license n° 9611), 2014-present
• Certification of Cranio-sacral Therapist Belgian Cranio-Sacral & Meditation Society, Belgium, 2005-present
• Certification Adult Practitioner Level 2 in "Cognitive Therapeutic Exercises" (aka "Cognitive Multisensory Rehabilitation") 2001-present

Awards & Recognition

• Service Commendation American Congress of Rehabilitation Medicine for Task Force Co-Chair Measurement Interdisciplinary Special Interest Group Rasch Reporting Guidelines. 2021
• Elite Reviewer for 2019 for the Archives of Physical Medicine and Rehabilitation in Grantsmanship for Rehabilitation Research (TIGRR) Fellowship, 2019-2020 (Sponsored by NIH/NICHD)
• APTA Early Career Award, 2016
• Training in Grantsmanship for Rehabilitation Research (TIGRR) Fellowship, 2014

Professional Associations

• American Physical Therapy Association (APTA)
  • Research
  • Neurology
• American Heart Association (AHA)
• American Congress of Rehabilitation Medicine
  • Task Force: Movement, Stroke-Interdisciplinary Special Interest Group (ISIG), Measurement Networking Group, Terminology, Complimentary Integrative Rehab Med
  • Section Member: Measurements, Geriatric Rehab, Neuroplasticity, Complementary Integrative Rehab Med, Stroke ISIG

Bio

I hold the Drs. T. J. and Ella M. Arneson Land-Grant Chair in Human Behavior at the University of Minnesota where I am a Professor of Psychiatry and Director for Adult Mental Health Research. I began my undergraduate work at the Massachusetts Institute of Technology, completing my Bachelor and MD degrees at Johns Hopkins University. I completed a psychiatry residency and fellowship in neuroimaging at Stanford University where he also served on the faculty in the Department of Psychiatry. I joined the University of Minnesota in 2001.My research interest is in the use of neuroimaging approaches to identify circuit abnormalities in brain disorders such as schizophrenia, traumatic brain injury and addiction and then to use these circuits as treatment targets for noninvasive neuromodulation interventions. I have over 300 publications, with many as first or last author, 23,000 citations, and an h-index of 87.In 2020, I was awarded the "Dean's Distinguished Lectureship Award" for reaching more than 1,000 citations of a 1994 paper that I helped author titled, A Quantitative Magnetic Resonance Imaging Study of Changes in Brain Morphology from Infancy to Late Adulthood . The paper is cited as evidence that MRI can be used to measure the living human brain.Within the university, I am a member of the Medical School Research Council , and KL2 Seminar Director for the Clinical and Translational Scientific Institute (CTSI).

Research Summary

Dr. Lim's research interest is in the use of neuroimaging approaches to identify circuit abnormalities in brain disorders such as schizophrenia, traumatic brain injury and addiction and then to use these circuits as treatment targets for noninvasive neuromodulation interventions.

Bio

Dr. Leslie Morse obtained her Doctor of Osteopathic Medicine degree from the University of New England College of Osteopathic Medicine followed by her residency in Physical Medicine and Rehabilitation at Boston Medical Center. She is board certified by the American Board of Physical Medicine and Rehabilitation. Dr. Morse continues to work on local and national level to promote the field of rehabilitation medicine. 

Expertise

Therapeutic outcome analysis, stem cell therapy for spinal cord injury, osteoclast biology, gait training and analysis

Awards & Recognition

• 2020 American Paraplegia Society Excellence Award, Academy of Spinal Cord Injury Professionals (ASCIP)
• 2021 Rebecca “Becky” J. Adcock, PhD Award for Excellence in Mentoring, Academy of Spinal Cord Injury Professionals (ASCIP)

Professional Associations

• Member, Research Committee Member, Association of Academic Physiatrists
• International Society for Clinical Densitometry

Research Summary

Research Summary/Interests

Dr. Morse's research interests include the impact of mechanical unloading on bone metabolism and the development of novel stem cell therapies for motor recovery after SCI. 

Research Funding Grants

• Department of Defense
  SCI170159
  Role: Co-investigator
  2018 - 2022
  Assistive Technology and Functional Outcomes following Spinal Cord Injury (Monden PI) 
  The aims of this study are to: (1) examine perceived barriers to or facilitators of assistive technology (AT) access and utilization and the impact on functional and psychosocial outcomes after tetraplegia, (2) assess for variations in use of AT across insurance providers and socioeconomic status in Veterans and civilians with tetraplegia, (3) assess the relationship between AT use and productivity (employment/school), and (4) assess the relationship between AT and psychosocial outcomes.
• NIDILRR, Department of Health and Human Services
  90SI5015-01-00
  Role: Co-Project Director
  2016 - 2022
  Rocky Mountain Regional Spinal Injury System 
  The goals of this project are to (1) harness our existing multidisciplinary system of rehabilitation care designed specifically to meet the needs of individuals with SCI to extend the Model Systems knowledge base, (2) contribute to improving long term SCI outcomes through participation in site-specific and collaborative clinical trials and research projects, (3) contribute to the SCI model systems national database through longitudinal assessment of long term SCI outcomes, (4) Contribute to improved long term SCI outcomes by conducting a research project designed to reduce sublesional neuropathic pain following SCI.
• NIDILRR, Department of Health and Human Services
  H133A150065 (Nash PI)
  Role: Co-investigator
  2016 - 2021
  Lifestyle intervention targeting enhanced health and function for persons with chronic SCI in caregiver/care-receiver relationships: effects of caregiver co-treatment
  The goals of this project are to: 1) determine the efficacy of a lifestyle intervention to improve health and function of individuals with SCI.
• Department of Defense
  W81XWH-14-SCIRP-CTA
  Role: PI
  2015 - 2022
  Effects of Ekso-assisted gait training on Bone Health and Quality of Life: A Randomized Clinical Trial
  The goals of this project are to 1) determine whether exoskeleton-assisted gait training increases bone strength in the paralyzed lower extremity and 2) determine whether exoskeleton-assisted gait training improves quality of life after SCI. Secondarily, to determine whether gait training improves the following related outcomes and mediators of quality of life: mood, pain, and cortical activity of related emotional networks in the brain.
• NIH/NIAMS
  R01 AR064793-01A1 (Battaglino PI)
  Role: Co-investigator
  2015 - 2022
  Regulation of gastric and osteoclast acidification by Snx10
  The specific aims to be addressed in this project are: 1) Determine the cellular mechanisms by which Snx10 regulates osteoclast function. 2) Determine the role of osteoclastic expression of Snx10 on bone homeostasis in vivo. 3) Determine the whole of gastric expression of Snx10 on bone homeostasis in vivo.

Clinical Summary

Board Certifications

Physical Medicine and Rehabilitation (ABPMR)