Oyedele Adeyi
,
Credentials
MD

Professor
Biography

Bio

Dr. Adeyi is an anatomic pathologist with expertise in liver and transplantation pathology. His clinical practice covers medical, transplant and oncologic diseases of the liver, with more than 15 years' experience as a hepatobiliary pathology sub-specialist. His primary research interest is in transplant and tumor immunology. During his career he has combined an active clinical service with research and teaching as well as participating locally, nationally, and internationally as a key resource in medical, transplantation and oncologic liver diseases.Adeyi's research has focused on the interplay between the immune system on the one hand and allogeneic, tumor and viral antigens on the other. In collaboration he has used murine and pig models to study varying aspects of alloimmunity, infections, and tumorigenesis in modified immunologic backgrounds, with a view to understanding how best to utilize the innate and specific immune systems in achieving better outcomes in solid organ transplantation and malignancies, as well as viral infections and organ preservation injury.

Research Summary

Transplant and tumor immunology

Publications

  • Barrow F, Khan S, Fredrickson G, Wang H, Dietsche K, Parthiban P, Robert S, Kaiser T, Winer S, Herman A, Adeyi O, Mouzaki M, Khoruts A, Hogquist KA, Staley C, Winer DA, Revelo XS.  Microbiota-driven activation of intrahepatic B cells aggravates NASH through innate and adaptive signaling. Hepatology. 2021 Aug;74(2):704-722
  • Moini M, Onofrio F, Hansen BE, Adeyi O, Khalili K, Patel K.  Combination of FIB-4 with ultrasound surface nodularity or elastography as predictors of histologic advanced liver fibrosis in chronic liver disease. Sci Rep. 2021 Sep 29;11(1):19275
  • Kosick HM, Keyrouz A, Adeyi O, Sebastiani G, Patel K. A.  Stepwise algorithmic approach and external validation study for noninvasive prediction of advanced fibrosis in nonalcoholic fatty liver disease. Dig Dis Sci. 2021 Nov;66(11):4046-4057
  • Fredrickson G, Barrow F, Dietsche K, Parthiban P, Khan S, Robert S, Demirchian M, Rhoades H, Wang H, Adeyi O, Revelo XS. Exercise of high intensity ameliorates hepatic inflammation and the progression of NASH. Mol Metab. 2021 Nov;53:101270
  • Gonzalez RS, Raza A, Propst R, Adeyi O, Bateman J, Sopha SC, Shaw J, Auerbach A.  Recent advances in digestive tract tumors: Updates from the 5th Edition of the World Health Organization "Blue Book". Arch Pathol Lab Med. 2021 May 1;145(5):607-626
  • Arif D, Mettler T, Adeyi OA. Mimics of hepatocellular carcinoma: a review and an approach to avoiding histopathological diagnostic missteps. Hum Pathol. 2021 Jun;112:116-127.