Apostolos Georgopoulos, MD, PhD
Professor, Department of Neuroscience
Professor, Department of Neuroscience
Regents Professor of Neuroscience
McKnight Presidential Chair in Cognitive Neuroscience
Director and American Legion Brain Sciences Chair, Brain Sciences Center
Professor of Neuroscience, Neurology, and Psychiatry
Affiliate Faculty, Institute for Health Informatics (IHI)
Affiliate Faculty, Center for Cognitive Sciences
MD, University of Athens School of Medicine
Ph.D. degree in Physiology, University of Athens, Greece, 1969
Research
Research Summary/Interests
Brain Mechanisms of Movement and Cognition; Functional Brain Biomarkers; Cortical Networks
There three major goals of our research: First, to elucidate the neural mechanisms underlying motor control and cognitive processing; second, to develop functional brain biomarkers for various brain diseases; and third, to understand the workings of developing cortical networks. For the first aim, we pursue experimental psychological studies, neurophysiological recordings, functional magnetic resonance imaging (MRI) at high fields (3, 4 and 7 Tesla), magnetoencephalography (MEG), and neural network modeling (using a supercomputer). For the second aim, we use MEG. And for the third aim, we record electrical activity from embryonic cortical cell cultures using multielectrode arrays.
- Magnetoencephalography of brain function
- Neural mechanisms of cognitive processes
- Neurophysiology of motor control and cognition
- Functional MRI of motor and cognitive processes
Publications
Christova, P & Georgopoulos, AP 2018, 'Invariant and heritable local cortical organization as revealed by fMRI' Journal of neurophysiology, vol. 120, no. 2, pp. 760-764. https://doi.org/10.1152/jn.00137.2018
Carpenter, A, Baud-Bovy, G, Georgopoulos, AP & Pellizzer, G 2018, 'Encoding of serial order in working memory: Neuronal activity in motor, premotor, and prefrontal cortex during a memory scanning task' Journal of Neuroscience, vol. 38, no. 21, pp. 4912-4933. https://doi.org/10.1523/JNEUROSCI.3294-17.2018
James, LM, Dolan, S, Leuthold, AC, Engdahl, B, Georgopoulos, A & Georgopoulos, AP 2018, 'The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women' EBioMedicine, vol. 35, pp. 288-294. https://doi.org/10.1016/j.ebiom.2018.08.026
James, LM, Christova, P, Lewis, SM, Engdahl, B, Georgopoulos, A & Georgopoulos, AP 2018, 'Protective Effect of Human Leukocyte Antigen (HLA) Allele DRB1*13:02 on Age-Related Brain Gray Matter Volume Reduction in Healthy Women' EBioMedicine, vol. 29, pp. 31-37. https://doi.org/10.1016/j.ebiom.2018.02.005
Georgopoulos, AP & Georgopoulos, A 2017, 'The Beautiful Brain and the influence of Santiago Ramón y Cajal on medicine' JAMA - Journal of the American Medical Association, vol. 318, no. 6, pp. 502-504. https://doi.org/10.1001/jama.2017.9858
Georgopoulos, AP, James, LM, Carpenter, AF, Engdahl, BE, Leuthold, AC & Lewis, SM 2017, 'Gulf War illness (GWI) as a neuroimmune disease' Experimental Brain Research, vol. 235, no. 10, pp. 3217-3225. https://doi.org/10.1007/s00221-017-5050-0
Christova, P, James, LM, Engdahl, B, Lewis, SM, Carpenter, A & Georgopoulos, AP 2017, 'Subcortical brain atrophy in Gulf War Illness' Experimental Brain Research, vol. 235, no. 9, pp. 2777-2786. https://doi.org/10.1007/s00221-017-5010-8
James, LM, Engdahl, B & Georgopoulos, AP 2017, 'Apolipoprotein E: the resilience gene' Experimental Brain Research, vol. 235, no. 6, pp. 1853-1859. https://doi.org/10.1007/s00221-017-4941-4
James, LM, Christova, P, Engdahl, B, Lewis, SM, Carpenter, A & Georgopoulos, AP 2017, 'Human Leukocyte Antigen (HLA) and Gulf War Illness (GWI): HLA-DRB1*13:02 Spares Subcortical Atrophy in Gulf War Veterans' EBioMedicine, vol. 26, pp. 126-131. https://doi.org/10.1016/j.ebiom.2017.11.005
James, LM, Engdahl, B, Leuthold, AC & Georgopoulos, AP 2016, 'Brain Correlates of Human Leukocyte Antigen (HLA) Protection in Gulf War Illness (GWI)' EBioMedicine, vol. 13, pp. 72-79. https://doi.org/10.1016/j.ebiom.2016.10.019