Apostolos Georgopoulos, MD, PhD

Regents Professor
McKnight Presidential Chair in Cognitive Neuroscience, Department of Neuroscience

Apostolos Georgopoulos

Contact Info

omega@umn.edu

Office Phone 612-725-2282

Lab Address:
Brain Science Center, VAMC 11B

Regents Professor
McKnight Presidential Chair in Cognitive Neuroscience, Department of Neuroscience

Director and American Legion Brain Sciences Chair, Brain Sciences Center

Faculty, Graduate Program in Neuroscience

Professor of Neuroscience, Neurology, and Psychiatry

Affiliate Faculty, Institute for Health Informatics (IHI)

Affiliate Faculty, Center for Cognitive Sciences


MD, University of Athens School of Medicine

Ph.D. degree in Physiology, University of Athens, Greece, 1969

Research

Research Summary/Interests

Brain Mechanisms of Movement and Cognition; Functional Brain Biomarkers; Cortical Networks

There three major goals of our research: First, to elucidate the neural mechanisms underlying motor control and cognitive processing; second, to develop functional brain biomarkers for various brain diseases; and third, to understand the workings of developing cortical networks. For the first aim, we pursue experimental psychological studies, neurophysiological recordings, functional magnetic resonance imaging (MRI) at high fields (3, 4 and 7 Tesla), magnetoencephalography (MEG), and neural network modeling (using a supercomputer). For the second aim, we use MEG. And for the third aim, we record electrical activity from embryonic cortical cell cultures using multielectrode arrays.

  • Magnetoencephalography of brain function
  • Neural mechanisms of cognitive processes
  • Neurophysiology of motor control and cognition
  • Functional MRI of motor and cognitive processes

Publications

James, LM & Georgopoulos, AP 2019, 'Human leukocyte antigen as a key factor in preventing dementia and associated apolipoprotein E4 risk', Frontiers in Aging Neuroscience, vol. 11, no. APR, 82. https://doi.org/10.3389/fnagi.2019.00082

James LA, Engdahl BE, Johnson RA & Georgopoulos AP 2019, ‘Gulf War Illness and Inflammation: Association of symptom severity with C-reactive protein’ J Neurol Neuromed vol. 4, no. 2, pp. 15-19. https://doi.org/10.29245/2572.942X/2019/2.1245

James, LM, Dolan, S, Leuthold, AC, Engdahl, BE, Georgopoulos, A & Georgopoulos, AP 2018, 'The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women', EBioMedicine, vol. 35, pp. 288-294. https://doi.org/10.1016/j.ebiom.2018.08.026

Charonis, S, James, LM, Georgopoulos AP 2019, ‘In silico Analysis of the Binding Affinities of Antigenic Epitopes of Vaccines Administered to Gulf War Veterans to Specific HLA Class II Alleles Protective for Gulf War Illness’ J Neurol Neuromed, vol. 4, no. 5, pp. 23-30. https://doi.org/10.29245/2572.942X/2019/5.1257

Tsilibary, EP, Souto, EP, Kratzke, M, James, LM, Engdahl, BE & Georgopoulos AP 2019, ‘Anthrax and Gulf War Illness (GWI): Evidence for the Presence of Harmful Anthrax Antigen PA63 In the Serum of Veterans with GWI’ J Neurol Neuromed, vol. 4, no. 6, pp. 1-9. https://doi.org/10.29245/2572.942X/2019/6.1255

Christova, P & Georgopoulos, AP 2018, 'Invariant and heritable local cortical organization as revealed by fMRI' Journal of neurophysiology, vol. 120, no. 2, pp. 760-764. https://doi.org/10.1152/jn.00137.2018

Carpenter, A, Baud-Bovy, G, Georgopoulos, AP & Pellizzer, G 2018, 'Encoding of serial order in working memory: Neuronal activity in motor, premotor, and prefrontal cortex during a memory scanning task' Journal of Neuroscience, vol. 38, no. 21, pp. 4912-4933. https://doi.org/10.1523/JNEUROSCI.3294-17.2018

James, LM, Dolan, S, Leuthold, AC, Engdahl, B, Georgopoulos, A & Georgopoulos, AP 2018, 'The effects of human leukocyte antigen DRB1*13 and apolipoprotein E on age-related variability of synchronous neural interactions in healthy women' EBioMedicine, vol. 35, pp. 288-294. https://doi.org/10.1016/j.ebiom.2018.08.026

James, LM, Christova, P, Lewis, SM, Engdahl, B, Georgopoulos, A & Georgopoulos, AP 2018, 'Protective Effect of Human Leukocyte Antigen (HLA) Allele DRB1*13:02 on Age-Related Brain Gray Matter Volume Reduction in Healthy Women' EBioMedicine, vol. 29, pp. 31-37. https://doi.org/10.1016/j.ebiom.2018.02.005

Georgopoulos, AP & Georgopoulos, A 2017, 'The Beautiful Brain and the influence of Santiago Ramón y Cajal on medicine' JAMA - Journal of the American Medical Association, vol. 318, no. 6, pp. 502-504. https://doi.org/10.1001/jama.2017.9858