Małgorzata Marjańska
,
Credentials
PhD

Professor
Biography

Bio

Małgorzata (Gosia) Marjańska is a professor in the Department of Radiology. Dr. Marjańska received a B.S. in chemistry with minor in mathematics from Loyola University of Chicago and a Ph.D. in chemistry from the University of California at Berkeley. She joined the Center for Magnetic Resonance Research (CMRR) in 2002 as a post-doctoral fellow working with Prof. Kamil Ugurbil and subsequently became a research assistant professor two years later, and assistant professor in 2013. In 2015, she was promoted to an associate professor and in 2020 to a professor.

Dr. Marjańska first encountered magnetic resonance while working with Prof. Keith Jameson at Loyola University of Chicago, first learning and then training other undergraduates to operate a 300 MHz Varian system. During the summer after her 3rd year of undergraduate studies, she worked at Bell Laboratories with Dr. Peter Mirau on solid state NMR characterization of polymer films. In order to follow her interest in NMR, she decided to pursue a Ph.D. at the University of California at Berkeley in the group of Prof. Alexander Pines. Her thesis titled "Quantum Logic Gates, Local Field, Selective Excitation and Structural Studies of Dipolar Couplings in Oriented Molecules" was focused on NMR as a technique to study molecules dissolved in liquid crystals.

Research Summary

Dr. Marjańska is interested in developing MRS techniques for humans and rodents over a wide range of field strengths (3 T up to 16.4 T) and applications of those methods to study various diseases including Alzheimer’s disease, dystonia, depression, and brain tumors. Dr. Marjańska has been interested in 1H and heteronuclear MRS (13C and 2H), diffusion-weighted MRS and relaxometry. The long-term goal of her research is to develop and assess robust, non-invasive and repeatable MRS methods for discovery of quantitative biomarkers for clinical research and practice.

Education

PhD, University of California at Berkeley
Major: Chemistry

Fellowships, Residencies, and Visiting Engagements

Fulbright U.S. Scholar Program, Fellowship
Sorbonne Université, Hopital Pitié-Salpêtrière
France

Honors and Recognition

Fellow, International Society of Magnetic Resonance in Medicine (ISMRM)
Fulbright U.S. Scholar Program Award, Sorbonne Université, Hopital Pitié-Salpêtrière, France

Professional Memberships

International Society of Magnetic Resonance in Medicine, Member
Selected Publications

Selected Publications

Marjanska M, Deelchand DK, Kreis R, Team IMSGFC, 2022. Results and interpretation of a fitting challenge for MR spectroscopy set up by the MRS study group of ISMRM. Magn Reson Med, 87 (1): 11-32.
PubMed ID: 8616800.
Bolan PJ, Branzoli F, Di Stefano AL,, Nichelli L, Valabregue R, Saunders SL, Akcakaya M, Sanson M, Lehericy S, Marjanska M, 2020. Automated acquisition planning for magnetic resonance spectroscopy in brain cancer. Med Image Comput Comput Assist Interv, 12267 730-739.
PubMed ID: 8735854.
Branzoli F, Deelchand DK, Sanson M, Lehericy S, Marjanska M, 2019. In vivo 1H MRS detection of cystathionine in human brain tumors. Magn Reson Med, 82 (4): 1259-1265.
PubMed ID: 6626581.
Branzoli F, Pontoizeau C, Tchara L, Di Stefano AL, Kamoun A, Deelchand DK, Valabregue R, Lehericy S, Sanson M, Ottolenghi C, Marjanska M, 2019. Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy. Neuro Oncol, 21 (6): 765-774.
PubMed ID: 6556848.
Branzoli F, Di Stefano AL, Capelle L, Ottolenghi C, Valabregue R, Deelchand DK, Bielle F, Villa C, Baussart B, Lehericy S, Sanson M, Marjanska M, 2018. Highly specific determination of IDH status using edited in vivo magnetic resonance spectroscopy. Neuro Oncol, 20 (7): 907-916.
PubMed ID: 6007442.
Marjanska M, McCarten JR, Hodges J, Hemmy LS, Grant A, Deelchand DK, Terpstra M, 2017. Region-specific aging of the human brain as evidenced by neurochemical profiles measured noninvasively in the posterior cingulate cortex and the occipital lobe using 1H magnetic resonance spectroscopy at 7 T. Neuroscience, 354 168-177.
PubMed ID: 5516630.
Tremblay S, Beaule V, Proulx S, Lafleur LP, Doyon J, Marjanska M, Theoret H, 2014. The use of magnetic resonance spectroscopy as a tool for the measurement of bi-hemispheric transcranial electric stimulation effects on primary motor cortex metabolism. J Vis Exp, (93): e51631.
PubMed ID: 4354197.
Marjanska M, Auerbach EJ, Valabregue R, Van de Moortele PF, Adriany G, Garwood M, 2012. Localized 1H NMR spectroscopy in different regions of human brain in vivo at 7 T: T2 relaxation times and concentrations of cerebral metabolites. NMR Biomed, 25 (2): 332-339.
PubMed ID: 3357544.
Marjanska M, Iltis I, Shestov AA, Deelchand DK, Nelson C, Ugurbil K, Henry PG, 2010. In vivo 13C spectroscopy in the rat brain using hyperpolarized [1-13C]pyruvate and [2-13C]pyruvate. J Magn Reson, 206 (2): 210-218.
PubMed ID: 2939207.
Marjanska M, Curran GL, Wengenack TM, Henry PG, Bliss RL, Poduslo JF, Jack CR, Jr., Ugurbil K, Garwood M, 2005. Monitoring disease progression in transgenic mouse models of Alzheimer's disease with proton magnetic resonance spectroscopy. Proc Natl Acad Sci U S A, 102 (33): 11906-11910.
PubMed ID: 1188012.
Contact

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Address

2021 6th Street SE, Minneapolis, MN 55455