Jose Debes

Associate Professor of Medicine, Division of Infectious Diseases and International Medicine


Administrator Info
Name: Admin
Phone: 612-624-9996
Fax: 612-625-4410
Mail: Mayo Memorial Building, MMC 250, 420 Delaware Street S.E., Minneapolis, MN 55455

Dr. Debes graduated from medical school at Universidad Nacional de Cordoba in Argentina. Following his graduation he completed a postdoctoral research fellowship and Masters in Science-Molecular Biology at the Mayo Clinic. He later pursued residency in Internal Medicine and Fellowship in Gastroenterology and Hepatology both at the University of Minnesota. During his fellowship Dr. Debes was awarded an NIH NRSA-F32 grant to study regulation of gene expression by the hepatitis C virus. Dr. Debes leads international research networks in three continents conducting research on viral hepatitis and liver cancer with on-site activities in Tanzania, Ethiopia, Netherlands, Brazil, Ecuador and Argentina. Through these networks he has defined the epidemiology of liver cancer in South America and Africa and has exposed biomarkers for early detection of liver cancer. His research activities expand from public health implementation and education on viral hepatitis to molecular biology aspects to define the mechanisms of viral-related liver cancer. Dr. Debes serves in editorial boards of multiple research journals and has served as reviewer in a variety of NIH study sections.

Research Summary

Mechanisms of viral carcinogenesis in hepatocellular carcinoma; Single cell sequencing and immune-detection for prediction of liver cancer; Viral hepatitis in HIV; Education, prevention and treatment of hepatitis B and liver cancer in resource-limited settings

Research Funding
Grants American College of Gastroenterology AFMDP, Robert Wood Johnson Scholar National Institutes of Health Horizon 2020, EU University of Minnesota

Teaching Summary

Teaching Areas
Hepatology; Global Health; Translational research

Clinical Summary

Hepatology; Viral Hepatitis; HCC; Liver disease and HIV


MD, Universidad Nacional de Cordoba

Fellowships, Residencies, and Visiting Engagements

Internal Medicine, Residency
University of Minnesota Medical School
Gastroenterology and Hepatology, Fellowship
University of Minnesota Medical School

Honors and Recognition

Presidential Award, American College of Gastroenterology
National Research Science Award, NIH/NIDDK
Selected Publications

Selected Publications

Yang, J., Essa, M., Ashraf, O., Hend, I., Debes, J., Ocama, P., Olufunmilayo, A., Emuobor, E., Bello, R., Onyekwere, C., Ekere, F., Igetei, R., Ali, H., Gores, G., Topazian, M., Roberts, L., 2017. Clinical Characteristics, Management and Outcomes of Patients with Hepatocellular Carcinoma in Africa: A Multi-Country Observational Study from the Africa Liver Cancer Consortium. Lancet Gastroenterology and Hepatology,
Anugwom, C., Campbell, C., Lifson, A., Debes, J., Assessment of subclinical effects of Hepatitis E virus infection in the United States. Clinical Infectious Diseases,