Karen Ashe

Founding Director, N. Bud Grossman Center for Memory Research and Care
Edmund Wallace and Anne Marie Tulloch Chairs in Neurology and Neuroscience
Preceptor, Medical Scientist Training Program (Combined MD/PhD Training Program)
Graduate Program in Neuroscience


Karen Hsiao Ashe, MD, PhD, a professor in the Department of Neurology, is a pioneer in Alzheimer's disease research. Ashe has studied the disease for more than 26 years and in her 20 years at the University of Minnesota she has trained more than 40 undergraduate, doctoral and post-doctoral scientists. Ashe has made a commitment in training the next generation of great scientists, in particular developing the careers of translational scientists. Her primary research areas include the genetics of human prion diseases; transgenic models of prion and Alzheimer's diseases; and the molecular basis of memory loss in Alzheimer's disease. Ashe's current research interest involves the discovery of tau mutations that cause neurodegeneration. Ashe created tau transgenic mice to study tau-based mechanisms of memory loss and neurodegeneration. In 2006, Ashe became the founding Director of the N. Bud Grossman Center for Memory Research and Care, a tripartite endeavor encompassing basic, translational and clinical research and care in memory disorders.


MD, Harvard Medical School
Major: Harvard-MIT Health Sciences and Technology Program
PhD, Massachusetts Institute of Technology
Major: Psychology
BA, Magna cum laude, Harvard University
Major: Chemistry and Physics

Fellowships, Residencies, and Visiting Engagements

Residency in Neurology, Residency
University of California
San Francisco, California, United States



Medical Biosciences Building
2101 6th St SE
Minneapolis, MN 55455