Man Liu

Assistant Professor of Medicine


I have a broad background in physiology, with specific training and expertise in research areas such as ion channel mechanisms, patch clamp electrophysiology, Mg homeostasis, mitochondria, and ER stress. I have carried out electrophysiological experiments to study nicotinic acetylcholine receptors at neuromuscular junctions, voltage-gated cardiac sodium channel and other cardiac ion channels. I have been working on different cardiac disease mouse models (hypertension, MI, HFpEF) and cell models (acutely isolated/cultured cardiomyocytes and human iPSC-derived cardiomyocytes). Recently, I am focusing on studying Mg deficiency-induced cardiac diastolic dysfunction (DD) and Mg supplementation on improvement of DD and HFpEF.

Research Summary

Mg deficiency-induced cardiac diastolic dysfunction and HFpEF

Clinical Summary

Arrhythmia, Cardiac arrhythmia, Cardiac electrophysiology, Heart failure, Heart failure with preserved ejection fraction