Alexander Boucher, MD

Assistant Professor, Department of Pediatrics

Alexander Boucher

Contact Info

Office Address:
Pediatric Hematology/Oncology
A529 Mayo
420 Delaware Street SE
Minneapolis, MN 55455

Mailing Address:
Pediatric Hematology/Oncology
MMC 484 Mayo
420 Delaware St SE
Minneapolis, MN 55455

Administrative Assistant Name
Rick Jacobson

Administrative Email

MD, University of Tennessee College of Medicine, Memphis, TN

Residency in Internal Medicine-Pediatrics, University of Minnesota, Minneapolis, MN

Fellowship in Pediatric Hematology-Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH


Dr. Boucher graduated from the University of Tennessee College of Medicine. He then completed his internal medicine/pediatrics residency at the University of Minnesota, followed by his pediatric hematology/oncology fellowship at the Cincinnati Children’s Hospital Medical Center. He is a member of Alpha Omega Alpha and is board-certified in Internal Medicine and Pediatrics and is currently board-eligible for pediatric hematology/oncology.

He joined the University of Minnesota faculty as assistant professor of pediatric hematology in the Department of Pediatrics in 2019. He holds a joint appointment in the Department of Medicine. He takes care of patients with a wide range of non-malignant hematologic disorders. His specific interests include inherited hemoglobinopathies, especially sickle cell disease, as well as bleeding and clotting disorders.

In the Department of Medicine, his care will be focused on adolescents and young adults with sickle cell disease and the transition process. In doing so, his goal is to strengthen the growing comprehensive sickle cell programs at M Health Fairview across the lifespan through clinical care and research expansion.

Dr. Boucher's research includes improving patient-centered outcomes and community awareness for individuals with hemoglobinopathies like sickle cell disease and thalassemias. He is also engaged in clinical studies focused on researching prospective clinical biomarkers linking platelet activity and inflammatory responses as well as interdisciplinary approaches to optimizing antiplatelet therapy in pediatrics. He chose to return to Minnesota after fellowship because the program at UMN offered significant growth potential in these research fields as well as a ready support structure to improve care for young adults with hemoglobinopathies.

Awards & Recognition

  • Minnesota Monthly "Top Doctor" (2021)
  • Minneapolis - St. Paul “Top Doctors, Rising Star Edition” (2021)


Research Summary/Interests

  • Bleed and Clotting Disorders
  • Anemia
  • Platelet disorders
  • Sickle Cell Disorder
  • Thalassemia


  • Azul M, Shah S, Williams S, Vercellotti GM, Boucher AA. Evidence for complement-mediated bone marrow necrosis in a young adult with sickle cell disease. Blood Cells Mol Dis. 2021 Feb;86:102508. doi: 10.1016/j.bcmd.2020.102508. Epub 2020 Oct 9. PMID: 33096468; PMCID: PMC7546691.
  • Boucher AA, Dong M, Vinks AA, Marahatta A, Howard TA, Ware RE, Nathan JD, Abu-El-Haija M, Luchtman-Jones L. Hydroxyurea Pharmacokinetics in Pediatric Patients After Total Pancreatectomy With Islet Autotransplantation. J Clin Pharmacol. 2020 Oct 7. doi: 10.1002/jcph.1759. Epub ahead of print. PMID: 33029796.
  • Ali HM, Bellin MD, Boucher AA, Northup EF, Florek ER, Wilhelm JJ, Downs EM, Schwarzenberg SJ, Chinnakotla S. Safety and Clinical Outcomes of Using Low-Molecular-Weight Dextran During Islet Autotransplantation in Children. Pancreas. 2020 Jul;49(6):774-780. doi: 10.1097/MPA.0000000000001571. PMID: 32541632.
  • Hemoglobin Southampton complicated by cerebral ischemia, moyamoya, and hydroxyurea-induced methemoglobinemia. Boucher AA, Gurunathan A, Taylor JM, Ricci KW, Vadivelu S, Quinn CT. Am J Hematol. 2019 Aug;94(8):949-954. doi: 10.1002/ajh.25509. Epub 2019 Jun 7. No abstract available. PMID: 31095774
  • Thrombopoietin Contributes to Extreme Thrombocytosis After Pediatric Pancreatectomy With Islet Autotransplantation. Gurria JP, Boucher AA, Hornung L, Palumbo JS, Badia P, Luchtman-Jones L, Abu-El-Haija M, Lin TK, Nathan JD. Pancreas. 2019 May/Jun;48(5):652-655. doi: 10.1097/MPA.0000000000001313. PMID: 31091211 
  • Aspirin in childhood acute ischemic stroke: The evidence for treatment and efficacy testing. Boucher AA, Taylor JM, Luchtman-Jones L.Pediatr Blood Cancer. 2019 Jun;66(6):e27665. doi: 10.1002/pbc.27665. Epub 2019 Feb 14. Review. PMID: 30762284 
  • Utilization trends and safety of intravenous iron replacement in pediatric specialty care: A large retrospective cohort study. Boucher AA, Pfeiffer A, Bedel A, Young J, McGann PT. Pediatr Blood Cancer. 2018 Jun;65(6):e26995. doi: 10.1002/pbc.26995. Epub 2018 Jan 25. PMID: 29369486 
  • Successful liver transplantation for homozygous protein C deficiency with a type II mutation using a heterozygous living related donor. Boucher AA, Luchtman-Jones L, Nathan JD, Palumbo JS. Am J Hematol. 2018 Mar;93(3):462-466. doi: 10.1002/ajh.24998. Epub 2018 Jan 25. No abstract available. PMID: 29218739 


Board Certifications

  • American Board of Pediatrics
  • American Board of Internal Medicine-Hematology

Clinical Interests

Bleed and Clotting Disorders; Anemia; Platelet disorders; Sickle Cell Disorder; Thalassemia