Alexander Boucher, MD, FAAP

Assistant Professor, Department of Pediatrics

Alexander Boucher

Contact Info

Office Address:
Pediatric Hematology/Oncology
A529 Mayo
420 Delaware Street SE
Minneapolis, MN 55455

Mailing Address:
Pediatric Hematology/Oncology
MMC 484 Mayo
420 Delaware St SE
Minneapolis, MN 55455

Administrative Assistant Name
Rick Jacobson

Administrative Email

Assistant Professor, Department of Pediatrics

Faculty Member, Division of Pediatric Hematology and Oncology

Assistant Professor, Department of Medicine

Faculty Member, Division of Hematology, Oncology and Transplantation

Associate Program Director, Hematology-Focused Fellowship Training Program

MD, University of Tennessee College of Medicine, Memphis, TN

Residency in Internal Medicine-Pediatrics, University of Minnesota, Minneapolis, MN

Fellowship in Pediatric Hematology-Oncology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH


Dr. Boucher graduated from the University of Tennessee College of Medicine. He then completed his internal medicine/pediatrics residency at the University of Minnesota, followed by his pediatric hematology/oncology fellowship at the Cincinnati Children’s Hospital Medical Center. He is a member of Alpha Omega Alpha, is board-certified in Internal Medicine, Pediatrics, and Pediatric Hematology/Oncology.

He joined the University of Minnesota faculty as Assistant Professor of pediatric hematology in the Department of Pediatrics in 2019. He holds a joint appointment in the Department of Medicine. His specific interests include inherited hemoglobinopathies, especially sickle cell disease (SCD) and thalassemia, and addressing diversity, equity, and inclusion (DEI) issues in clinical care. He sees pediatric patients with a wide range of hematologic disorders including red cell disorders, cytopenias, and marrow failure disorders.

In the Department of Medicine, he directs the SCD program with a focus on addressing care gaps for adolescents and young adults with SCD and other red cell disorders. In doing so, his goal is to build a lifespan approach to red cell disorders, particularly SCD, and strengthen our clinical care approach and research expansion.

Dr. Boucher's research includes improving patient-centered outcomes and community awareness for individuals with hemoglobinopathies like SCD and thalassemias. He also conducts research focused on addressing health inequities in clinical care, hematologic and otherwise. He is engaged in medical education for classical hematology and in curriculum development around social determinants of health.

Awards & Recognition

  • Alpha Omega Alpha
  • Arnold P. Gold Humanism in Medicine Honor Society
  • American Society of Hematology Medical Educator Institute
  • Minnesota Monthly "Top Doctor" (2021)
  • Minneapolis - St. Paul “Top Doctors, Rising Star Edition” (2021, 2022)


Research Summary/Interests

  • Bleed and Clotting Disorders
  • Anemia
  • Platelet disorders
  • Sickle Cell Disorder
  • Thalassemia


  • Boucher AA, Francisco BJ, Pfeiffer A, Martin M, Martin J, Shova A, Nathan JD, Tiao GM, Luchtman-Jones L. Urinary 11-dehydrothromboxane B2 aspirin efficacy testing is sensitive to perioperative inflammation in pediatric solid-organ transplant patients.Pediatr Blood Cancer. 2021 Oct 22:e29413. doi: 10.1002/pbc.29413. PMID: 34676969
  • Boucher AA, Bedel A, Jones S, Lenahan SF, Geer R, McGann PT. A retrospective study of the safety and efficacy of low molecular weight iron dextran for children with iron deficiency anemia. Pediatr Blood Cancer. 2021 Jul;68(7):e29024. doi: 10.1002/pbc.29024. Epub 2021 Mar 26.PMID: 33769677
  • Scheuer J, Lehman A, Howard CR, Greengard E, Boucher AA. Multifocal bone pain, fevers, and a clavicular lesion in an 11 year old Liberian male. Pediatr Rev 2021 Mar;42(3):147-150. doi: 10.1542/pir.2020-0034. PMID: 33648993
  • Boucher AA, Wastvedt S, Hodges JS, Beilman GJ, Kirchner VA, Pruett TL, Hering BJ, Schwarzenberg SJ, Downs E, Freeman M, Trikudanathan G, Chinnakotla S, Bellin MD. Portal vein thrombosis may be more strongly associated with islet infusion than extreme thrombocytosis after total pancreatectomy with islet autotransplantation. Transplantation 2021 Jan 19. doi: 10.1097/TP.0000000000003624. PMID: 33988346Azul M, Shah S, Williams S, Vercellotti GM, Boucher AA. Evidence for complement-mediated bone marrow necrosis in a young adult with sickle cell disease. Blood Cells Mol Dis. 2021 Feb;86:102508. doi: 10.1016/j.bcmd.2020.102508. Epub 2020 Oct 9. PMID: 33096468; PMCID: PMC7546691.
  • Boucher AA, Dong M, Vinks AA, Marahatta A, Howard TA, Ware RE, Nathan JD, Abu-El-Haija M, Luchtman-Jones L. Hydroxyurea Pharmacokinetics in Pediatric Patients After Total Pancreatectomy With Islet Autotransplantation. J Clin Pharmacol. 2020 Oct 7. doi: 10.1002/jcph.1759. Epub ahead of print. PMID: 33029796.
  • Ali HM, Bellin MD, Boucher AA, Northup EF, Florek ER, Wilhelm JJ, Downs EM, Schwarzenberg SJ, Chinnakotla S. Safety and Clinical Outcomes of Using Low-Molecular-Weight Dextran During Islet Autotransplantation in Children. Pancreas. 2020 Jul;49(6):774-780. doi: 10.1097/MPA.0000000000001571. PMID: 32541632.
  • Hemoglobin Southampton complicated by cerebral ischemia, moyamoya, and hydroxyurea-induced methemoglobinemia. Boucher AA, Gurunathan A, Taylor JM, Ricci KW, Vadivelu S, Quinn CT. Am J Hematol. 2019 Aug;94(8):949-954. doi: 10.1002/ajh.25509. Epub 2019 Jun 7. No abstract available. PMID: 31095774
  • Thrombopoietin Contributes to Extreme Thrombocytosis After Pediatric Pancreatectomy With Islet Autotransplantation. Gurria JP, Boucher AA, Hornung L, Palumbo JS, Badia P, Luchtman-Jones L, Abu-El-Haija M, Lin TK, Nathan JD. Pancreas. 2019 May/Jun;48(5):652-655. doi: 10.1097/MPA.0000000000001313. PMID: 31091211 
  • Aspirin in childhood acute ischemic stroke: The evidence for treatment and efficacy testing. Boucher AA, Taylor JM, Luchtman-Jones L.Pediatr Blood Cancer. 2019 Jun;66(6):e27665. doi: 10.1002/pbc.27665. Epub 2019 Feb 14. Review. PMID: 30762284 
  • Utilization trends and safety of intravenous iron replacement in pediatric specialty care: A large retrospective cohort study. Boucher AA, Pfeiffer A, Bedel A, Young J, McGann PT. Pediatr Blood Cancer. 2018 Jun;65(6):e26995. doi: 10.1002/pbc.26995. Epub 2018 Jan 25. PMID: 29369486 
  • Successful liver transplantation for homozygous protein C deficiency with a type II mutation using a heterozygous living related donor. Boucher AA, Luchtman-Jones L, Nathan JD, Palumbo JS. Am J Hematol. 2018 Mar;93(3):462-466. doi: 10.1002/ajh.24998. Epub 2018 Jan 25. No abstract available. PMID: 29218739 


Board Certifications

  • American Board of Pediatrics
  • American Board of Internal Medicine
  • American Board of Pediatrics--Pediatric Hematology/Oncology

Clinical Interests

Bleed and Clotting Disorders; Anemia; Platelet disorders; Sickle Cell Disorder; Thalassemia