Daniel Duprez
,
Credentials
MD, PhD, FAHA, FACC, FESC, FASH, FNLA, FASPC
Bio
Administrator Info
Name: Roberta Beach
Email: rmbeach@umphysicians.umn.edu
Mail: 420 Delaware Street SE
MMC 508 Mayo
8508A (Campus Delivery Code)
Minneapolis, MN 55455
Summary
Daniel Duprez, MD, PhD was born in Belgium and received his MD and PhD degree at the University of Ghent in Belgium. He completed his medicine residency and cardiology fellowship at the University of Ghent, followed by a fellowship at Mayo Clinic, Rochester, MN. He obtained a Hospital Management degree at the Catholic University of Leuven, Belgium. He was Professor Medicine/Cardiology at the University Ghent Belgium. In 2002, he joined the University of Minnesota, where he is tenured Professor of Medicine/Cardiology, holder of the Donald and Patricia Garofalo Chair in Preventive Cardiology at the School of Medicine and Adjunct Professor of Epidemiology and Community Health at the School of Public Health.My clinic research is focused on early detection and treatment of cardiovascular disease, arterial stiffness/elasticity in health and disease, lipids and novel biomarkers of inflammation and thrombosis in different ethnicities (CARDIA study, MESA study population, HIV population). I have received multiple NIH grants in these domains. I am a clinical trialist and I have studied dozens of new compounds of clinical trials in phase II, III and IV and have served on many study committees regarding design and adjudication events committees of international outcome trials.I serve at different NIH scientific grant review committees in USA, at different scientific grant committees of several European countries (Belgium, UK, France, Italy, Czech Republic, Poland), South Africa, United Arabic Emirates, Singapore. I have been involved in international education programs with the European Union regarding review and development.As a clinician, I focus on early detection of cardiovascular disease, lipid abnormalities, hypertension, and prevention of established atherosclerotic cardiovascular disease.
Research Summary
Mathematical modeling of the arterial system, arterial stiffness, diagnostic and predictive value in clinical setting and epidemiological study cohorts (MESA study cohort- NIH grants) Role of ethnicity on the predictive value of phenotypes of cardiovascular structure and function, biomarkers of inflammation, coagulation, lipoprotein particles and cardiovascular outcome (MESA study and CARDIA study – NIH grants) Lipoproteins, arterial stiffness, inflammatory markers in HIV patients and target organ damage and outcome (SMART and START – NIH grants) Clinical mechanistic, pharmacodynamics and outcome studies with new therapeutic compounds in the area of hypercholesterolemia/hypertriglyceridemia, hypertension, primary and secondary cardiovascular prevention (phase II, III, IV) Predictive value of cardiovascular biostatistical vs phenotype parameters in the Rasmussen Center for Cardiovascular Disease Prevention (philanthropy)
Teaching Summary
- Lipid abnormalities
- Arterial Mechanics
- Arterial stiffness
- Ventriculo-vascular coupling
- Structural and functional cardiovascular abnormalities
- Study cohorts
- Clinical trials and design (Phase II, III, IV)
- Cardiovascular Disease
- Epidemiology and Public Health