Mo Chen, PhD

Scientist, Department of Psychiatry

Mo Chen

Contact Info

mchen@umn.edu

Office Phone 612-624-5220

Office Address:
Room 247
717 Delaware St SE
Minneapolis, MN 55455

Scientist, Department of Psychiatry

Manager, MnDRIVE Non-invasive Neuromodulation Laboratory


PhD, Biomedical Engineering, Zhejiang University, 2012

BS, Biomedical Engineering, Zhejiang University, 2006

Summary

Dr. Mo Chen is the Manager of the Non-invasive Neuromodulation Laboratory and a Scientist in the Department of Psychiatry at the University of Minnesota. He obtained his B.S and PhD degrees in Biomedical Engineering from Zhejiang University and finished Postdoctoral research training in the Brain Plasticity Laboratory at University of Minnesota. His research interests are 1. investigating the mechanism and effectiveness of non-invasive neuromodulation techniques, including transcranial magnetic stimulation (TMS), repetitive TMS (rTMS), transcranial current stimulation (tDCS, tACS, tRNS, tPCS), paired associative stimulation (PAS).. etc. 2. Combining neuroimaging (functional magnetic resonance image, fMRI, resting-state fMRI and diffusion tensor imaging, DTI) and neuromodulation techniques to investigate pathophysiology of neurological and psychiatric disorders, e.g. Focal Dystonia, Spasmodic Dysphonia and Stroke. 3. Using neuromodulation techniques as a treatment to neurological or psychiatric disorders.

Expertise

Transcranial Magnetic Stimulation (TMS), repetitive TMS (rTMS), transcranial current stimulation (tDCS, tACS, tRNS, tPCS), paired associative stimulation (PAS), Eyeblink classical conditioning (EBCC), task functional magnetic resonance imaging (fMRI), resting-state fMRI, Neuromodulation.

Research

Research Funding Grants

Role: Principal Investigator. #507405. Office of Vice President for Research, University of Minnesota. Closed-loop Neuromodulation Platform Grant.

Role: Site PI at University of Minnesota; Co-investigator. 1R01DC015216-01A1. National Institutes of Health (NIH): National Institute for Deafness and Communication Disorders (NIDCD). Multimodal Assessment of Neurophysiology in Focal Dystonia. PI: Teresa J. Kimberley

Role: Co-investigator. W81XWH2010928. Medical Command. Control Network Neuromodulation to Enhance Cognitive Training in Complex Traumatic Brain Injury. PI: Davin Quinn.

Role: Co-investigator. R61MH123754. National Institutes of Health (NIH): National Institute of Mental Health (NIMH). Transcranial Magnetic Stimulation to Augment Behavior Therapy for Tics. PI: Christine Conelea.

Patents

  • Pang PMK, Chen M, Ho SK, Zhou HF, Ng DTW, Tong KY. Wearable power assistive device for helping a user to move their hand. US patent. US 20100305717A1.
  • Ye XS, Chen M, Wang P, Wang QB, Liu J, Zheng XX. Implanted microchip for neural recording and stimulating. CN patent. CN200710156513.1.
  • Chen WD, Dai JH, Zhang SM, Su Y, Chen M, Wang QB, Liu J, Zheng XX. A rehabilitation system based on virtual reality and functional electrical stimulation. CN patent. CN101574297B.
  • Tong KY, Ho SK, Chan TW, Chen M. Recovering system for training user to move hands, International patent, EP2436358 A4.

Publications

Chen M, Cline CC, Frost KL, et al. Chapter: Advances and challenges in TMS research on motor systems. Book: Engineering in Medicine: Advances and Opportunities. Edited by Laizzo P. and He B. Elsevier Press. Philadelphia. ISBN-13: 978-0128130681. Academic Press; 1 edition (December 5, 2018)

Chen M, Summers RLS, Prudente CN, Goding GS, Samargia-Grivettee S, Ludlow CL, Kimberley TJ. Transcranial magnetic stimulation and functional magnet resonance imaging evaluation of adductor spasmodic dysphonia during phonation. Brain Stimulation. https://doi.org/10.1016/j.brs.2020.03.003.

Chen M, Lixandrao MC, Prudente CN, Summers RLS, Kimberley TJ. 2018. Short interval intracortical inhibition responses to low-frequency repetitive transcranial magnetic stimulation under multiple interstimulus intervals and conditioning intensities. Neuromodulation. doi:10.1111/ner.12773

Chen M, Summers RLS, Goding GS, Samargia S, Ludlow CL, Prudente CN and Kimberley TJ. 2017. Evaluation of the Cortical Silent Period of the Laryngeal Motor Cortex in Healthy Individuals. Front. Neurosci. 11:88. doi: 10.3389/fnins.2017.00088

Schmidt RL*, Chen M*, Kimberley TJ*. 2017. Cortical excitability measurements are valid and reliable with intramuscular electromyography. PloS One. DOI:10.1371/journal.pone.0172152. * Authors contributed equally.

Chen M, Deng H, Schmidt RL, Kimberley TJ. 2015. Low-Frequency Repetitive Transcranial Magnetic Stimulation Targeted to Premotor Cortex Followed by Primary Motor Cortex Modulates Excitability Differently Than Premotor Cortex or Primary Motor Cortex Stimulation Alone. Neuromodulation. 18(8):678-85. doi: 10.1111/ner.12337

Chen M, Wu B, Lou X, Zhao T, Li J, Xu Z, Hu X, Zheng X. 2013. A Self-Adaptive Foot Drop Corrector Using Functional Electrical Stimulation Modulated by Tibialis Anterior EMG Dataset. Med Eng Phys. 35(2):195-204. doi: 10.1016/j.medengphy.2012.04.016